STRINGSTRING
MVB12B MVB12B TMEM50A TMEM50A LEPROT LEPROT CHMP2A CHMP2A VPS37B VPS37B HGS HGS SNF8 SNF8 VPS25 VPS25 VPS36 VPS36 VTA1 VTA1 VPS37A VPS37A CHMP7 CHMP7 PTPN23 PTPN23 STAM2 STAM2 CHMP4A CHMP4A LEPROTL1 LEPROTL1 CHMP4C CHMP4C STAM STAM CHMP4B CHMP4B PIK3R4 PIK3R4 UBAP1 UBAP1 TMEM50B TMEM50B VPS28 VPS28 MVB12A MVB12A TSG101 TSG101 VPS4A VPS4A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MVB12BMultivesicular body subunit 12B. (321 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
LEPROTLeptin receptor overlapping transcript. (131 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
VTA1Vesicle trafficking 1. (307 aa)
VPS37AVPS37A subunit of ESCRT-I. (396 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1632 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
CHMP4ACharged multivesicular body protein 4A. (222 aa)
LEPROTL1Leptin receptor overlapping transcript like 1. (131 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
STAMSignal transducing adaptor molecule. (540 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
UBAP1Ubiquitin associated protein 1. (502 aa)
TMEM50BTransmembrane protein 50B. (158 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (231 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
TSG101Tumor susceptibility 101. (390 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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