STRINGSTRING
PLOD3 PLOD3 EDNRB EDNRB MESP1 MESP1 NR2F2 NR2F2 SOX18 SOX18 HEY2 HEY2 STC1 STC1 PDE4D PDE4D EDF1 EDF1 ACVR1 ACVR1 NOTCH1 NOTCH1 SMAD4 SMAD4 EDNRA EDNRA RAPGEF2 RAPGEF2 RDX RDX F11R F11R HOXB5 HOXB5 ROBO4 ROBO4 HAPLN2 HAPLN2 FASN FASN RAP1A RAP1A GSTM3 GSTM3 TIE1 TIE1 CLIC4 CLIC4 PDPN PDPN TMEM100 TMEM100 S1PR1 S1PR1 ENSCSAP00000018022 ENSCSAP00000018022 ENSCSAP00000018065 ENSCSAP00000018065 FZD2 FZD2 FZD1 FZD1 CLDN3 CLDN3 NRG1 NRG1 MARVELD2 MARVELD2 MYADM MYADM CCM2 CCM2 PROX1 PROX1 RAPGEF1 RAPGEF1 SOX17 SOX17 ACVR2B ACVR2B MYD88 MYD88 HOXA13 HOXA13 ENSCSAP00000010271 ENSCSAP00000010271 DMD DMD PPP1R16B PPP1R16B JAG1 JAG1 HEY1 HEY1 EZR EZR AFDN AFDN ARHGEF26 ARHGEF26 MSN MSN DLL1 DLL1 NRP1 NRP1 KDM6B KDM6B COL15A1 COL15A1 TJP3 TJP3 MET MET BMPR2 BMPR2 TNMD TNMD PTPRS PTPRS COL22A1 COL22A1 NOTCH4 NOTCH4 CLDN1 CLDN1 HEG1 HEG1 RAP2C RAP2C COL18A1 COL18A1 FSTL1 FSTL1 BARX1 BARX1 TJP1 TJP1 RAPGEF3 RAPGEF3 ACVRL1 ACVRL1 VEZF1 VEZF1 SCUBE1 SCUBE1 KDR KDR HPSE HPSE RAP1B RAP1B PDE2A PDE2A PECAM1 PECAM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLOD3Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (736 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
SOX18SRY-box transcription factor 18. (363 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
STC1Stanniocalcin 1. (247 aa)
PDE4DPhosphodiesterase. (641 aa)
EDF1Endothelial differentiation related factor 1. (148 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NOTCH1Notch receptor 1. (2555 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1685 aa)
RDXRadixin. (605 aa)
F11RF11 receptor. (323 aa)
HOXB5Homeobox B5. (269 aa)
ROBO4Roundabout guidance receptor 4. (1061 aa)
HAPLN2Hyaluronan and proteoglycan link protein 2. (340 aa)
FASNFatty acid synthase. (2510 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GSTM3Glutathione S-transferase. (225 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
PDPNPodoplanin. (162 aa)
TMEM100Transmembrane protein 100. (134 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
ENSCSAP00000018022Uncharacterized protein. (184 aa)
ENSCSAP00000018065annotation not available (184 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (649 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
NRG1Neuregulin 1. (467 aa)
MARVELD2MARVEL domain containing 2. (559 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
CCM2CCM2 scaffold protein. (466 aa)
PROX1Prospero homeobox 1. (737 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1264 aa)
SOX17SRY-box transcription factor 17. (412 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
HOXA13Homeobox A13. (391 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
DMDUncharacterized protein. (774 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
EZREzrin. (584 aa)
AFDNAfadin, adherens junction formation factor. (1843 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (869 aa)
MSNMoesin. (577 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
KDM6BLysine demethylase 6B. (1640 aa)
COL15A1Uncharacterized protein. (1388 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (920 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1381 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TNMDTenomodulin. (317 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1941 aa)
COL22A1VWFA domain-containing protein. (1628 aa)
NOTCH4Notch receptor 4. (1994 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
HEG1Heart development protein with EGF like domains 1. (1323 aa)
RAP2CRAP2C, member of RAS oncogene family. (183 aa)
COL18A1LAM_G_DOMAIN domain-containing protein. (1213 aa)
FSTL1Follistatin like 1. (308 aa)
BARX1BARX homeobox 1. (254 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1784 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
VEZF1Vascular endothelial zinc finger 1. (520 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (630 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
HPSEHeparanase. (546 aa)
RAP1BUncharacterized protein. (184 aa)
PDE2APhosphodiesterase. (934 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (738 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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