STRINGSTRING
HMG20A HMG20A ISL2 ISL2 CNTN2 CNTN2 SIN3A SIN3A HOXD3 HOXD3 BCL11A BCL11A HOXA2 HOXA2 SIX1 SIX1 ENSCSAP00000010271 ENSCSAP00000010271 DMD DMD GPR37L1 GPR37L1 MAP3K13 MAP3K13 EYA1 EYA1 EIF4G1 EIF4G1 JAG1 JAG1 ASPM ASPM BMP2 BMP2 HEY1 HEY1 BEND6 BEND6 BRINP3 BRINP3 SIX3 SIX3 CYB5D2 CYB5D2 CDK5RAP2 CDK5RAP2 BRINP1 BRINP1 DLX6 DLX6 NLGN1 NLGN1 ECT2 ECT2 ESRP1 ESRP1 GDF6 GDF6 CDK5RAP1 CDK5RAP1 FEZF2 FEZF2 BRINP2 BRINP2 TCF3 TCF3 ZC4H2 ZC4H2 TCF12 TCF12 SOX8 SOX8 DLL1 DLL1 ZEB1 ZEB1 RELN RELN NRCAM NRCAM HMG20B HMG20B CNTN4 CNTN4 NKX2-2 NKX2-2 RET RET NTF3 NTF3 CXCL12 CXCL12 ENSCSAP00000007050 ENSCSAP00000007050 ALK ALK LMX1A LMX1A PBX1 PBX1 FEZF1 FEZF1 BCL11B BCL11B GDF5 GDF5 TGIF2 TGIF2 DUOXA1 DUOXA1 TLX3 TLX3 B2M B2M NKX2-5 NKX2-5 VWC2L VWC2L BCL6 BCL6 APP APP CTDSP1 CTDSP1 EIF4ENIF1 EIF4ENIF1 TRPC5 TRPC5 GATA2 GATA2 YWHAH YWHAH NCOA1 NCOA1 GDF7 GDF7 RNF112 RNF112 LTK LTK GPRC5B GPRC5B ID4 ID4 BMP6 BMP6 EIF2AK4 EIF2AK4 LRRK2 LRRK2 MOSMO MOSMO GSK3B GSK3B ID2 ID2 DKK1 DKK1 NEPRO NEPRO CALR CALR SHH SHH CDK5R1 CDK5R1 PRPF19 PRPF19 TBX6 TBX6 NOTCH3 NOTCH3 CNTF CNTF MMD MMD LBX1 LBX1 SPAG9 SPAG9 GDF11 GDF11 IRX3 IRX3 PAX6 PAX6 REST REST ZNF536 ZNF536 MAG MAG SOX9 SOX9 WDR62 WDR62 ZFHX3 ZFHX3 EIF4E EIF4E GDPD5 GDPD5 SOCS2 SOCS2 TIAM1 TIAM1 NR2E1 NR2E1 SFRP1 SFRP1 RHOA RHOA NREP NREP BMP4 BMP4 MEIS1 MEIS1 DLX1 DLX1 DLX2 DLX2 MEF2C MEF2C FGFR1 FGFR1 FOXA1 FOXA1 BMP7 BMP7 LSM1 LSM1 PROX1 PROX1 MAP1B MAP1B NOTCH1 NOTCH1 ZFHX2 ZFHX2 VWC2 VWC2 DPYSL2 DPYSL2 HEY2 HEY2 WNT3A WNT3A ISL1 ISL1 FGF20 FGF20 BIN1 BIN1 PHOX2B PHOX2B SH3GL3 SH3GL3 EDNRB EDNRB ROCK1 ROCK1 MMD2 MMD2 MIB1 MIB1 IMPACT IMPACT TCF4 TCF4 BCL2 BCL2 POU4F2 POU4F2 SFRP2 SFRP2 DIXDC1 DIXDC1 RARA RARA MED1 MED1 DDX6 DDX6 DTX1 DTX1 FEZ1 FEZ1 CDON CDON LRRC45 LRRC45 ARHGEF2 ARHGEF2 MYCL MYCL HEYL HEYL LIN28A LIN28A RAP1GAP RAP1GAP NBL1 NBL1 DISP3 DISP3 CASZ1 CASZ1 HES3 HES3 TP73 TP73 HES5 HES5 KCTD11 KCTD11 NEUROG1 NEUROG1 TRIM32 TRIM32 ATOH1 ATOH1 SOX11 SOX11 ENSCSAP00000017686 ENSCSAP00000017686 NGF NGF NEUROG3 NEUROG3 ZHX2 ZHX2 NEUROD1 NEUROD1 OLIG2 OLIG2 S1PR5 S1PR5 ASCL1 ASCL1 NEUROD2 NEUROD2 BDNF BDNF FOXG1 FOXG1 ADRA2B ADRA2B FERD3L FERD3L NTF4 NTF4 GLI3 GLI3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HMG20AHigh mobility group 20A. (347 aa)
ISL2ISL LIM homeobox 2. (359 aa)
CNTN2Contactin 2. (1040 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
HOXD3Homeobox D3. (432 aa)
BCL11AC2H2-type domain-containing protein. (243 aa)
HOXA2Homeobox A2. (373 aa)
SIX1SIX homeobox 1. (284 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
DMDUncharacterized protein. (774 aa)
GPR37L1G protein-coupled receptor 37 like 1. (481 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (586 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1565 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
ASPMAbnormal spindle microtubule assembly. (2794 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
BEND6BEN domain containing 6. (277 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (690 aa)
SIX3SIX homeobox 3. (331 aa)
CYB5D2Cytochrome b5 domain containing 2. (184 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1896 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
DLX6Distal-less homeobox 6. (175 aa)
NLGN1Neuroligin 1. (509 aa)
ECT2Epithelial cell transforming 2. (914 aa)
ESRP1Epithelial splicing regulatory protein 1. (663 aa)
GDF6Growth differentiation factor 6. (455 aa)
CDK5RAP1CDK5 regulatory subunit associated protein 1. (587 aa)
FEZF2FEZ family zinc finger 2. (458 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (783 aa)
TCF3Transcription factor 3. (581 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
TCF12Transcription factor 12. (682 aa)
SOX8SRY-box transcription factor 8. (446 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1124 aa)
RELNReelin. (3427 aa)
NRCAMNeuronal cell adhesion molecule. (1298 aa)
HMG20BHigh mobility group 20B. (317 aa)
CNTN4Contactin 4. (991 aa)
NKX2-2NK2 homeobox 2. (273 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1099 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
ENSCSAP00000007050Uncharacterized protein. (2022 aa)
ALKTyrosine-protein kinase receptor. (1192 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (295 aa)
PBX1PBX homeobox 1. (301 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
GDF5Growth differentiation factor 5. (499 aa)
TGIF2TGFB induced factor homeobox 2. (237 aa)
DUOXA1Dual oxidase maturation factor 1. (393 aa)
TLX3T cell leukemia homeobox 3. (291 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
NKX2-5NK2 homeobox 5. (324 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (174 aa)
BCL6BCL6 transcription repressor. (708 aa)
APPAmyloid beta precursor protein. (770 aa)
CTDSP1CTD small phosphatase 1. (260 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (984 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
GATA2GATA binding protein 2. (397 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
NCOA1Nuclear receptor coactivator. (1399 aa)
GDF7Growth differentiation factor 7. (447 aa)
RNF112Ring finger protein 112. (630 aa)
LTKTyrosine-protein kinase receptor. (864 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (403 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
MOSMOModulator of smoothened. (167 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
NEPRONucleolus and neural progenitor protein. (566 aa)
CALRCalreticulin. (417 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
TBX6T-box transcription factor 6. (436 aa)
NOTCH3Notch receptor 3. (1980 aa)
CNTFCiliary neurotrophic factor. (200 aa)
MMDMonocyte to macrophage differentiation associated. (238 aa)
LBX1Ladybird homeobox 1. (281 aa)
SPAG9Sperm associated antigen 9. (1334 aa)
GDF11Growth differentiation factor 11. (406 aa)
IRX3Iroquois homeobox 3. (416 aa)
PAX6Paired box 6. (436 aa)
RESTRE1 silencing transcription factor. (1096 aa)
ZNF536Zinc finger protein 536. (1301 aa)
MAGMyelin associated glycoprotein. (626 aa)
SOX9SRY-box transcription factor 9. (509 aa)
WDR62WD repeat domain 62. (1514 aa)
ZFHX3Zinc finger homeobox 3. (3699 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
GDPD5Glycerophosphodiester phosphodiesterase domain containing 5. (610 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1466 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
RHOARas homolog family member A. (193 aa)
NREPNeuronal regeneration related protein. (68 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
MEIS1Meis homeobox 1. (390 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Distal-less homeobox 2. (329 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
FGFR1Fibroblast growth factor receptor. (830 aa)
FOXA1Forkhead box A1. (470 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
PROX1Prospero homeobox 1. (737 aa)
MAP1BMicrotubule associated protein 1B. (2468 aa)
NOTCH1Notch receptor 1. (2555 aa)
ZFHX2Zinc finger homeobox 2. (2568 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
DPYSL2Dihydropyrimidinase like 2. (572 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ISL1ISL LIM homeobox 1. (349 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
BIN1Bridging integrator 1. (608 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (347 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MMD2Monocyte to macrophage differentiation associated 2. (246 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
IMPACTImpact RWD domain protein. (320 aa)
TCF4Transcription factor 4. (671 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
POU4F2POU domain protein. (407 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
DIXDC1DIX domain containing 1. (683 aa)
RARARetinoic acid receptor alpha. (462 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
DTX1Deltex E3 ubiquitin ligase 1. (624 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (978 aa)
MYCLMYCL proto-oncogene, bHLH transcription factor. (364 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
LIN28ALin-28 homolog A. (210 aa)
RAP1GAPRAP1 GTPase activating protein. (689 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (181 aa)
DISP3Dispatched RND transporter family member 3. (1392 aa)
CASZ1Uncharacterized protein. (1767 aa)
HES3Hes family bHLH transcription factor 3. (197 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
KCTD11Potassium channel tetramerization domain containing 11. (232 aa)
NEUROG1Neurogenin 1. (237 aa)
TRIM32Tripartite motif containing 32. (653 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
SOX11Transcription factor SOX. (441 aa)
ENSCSAP00000017686BHLH domain-containing protein. (358 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (241 aa)
NEUROG3Neurogenin 3. (215 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
OLIG2Oligodendrocyte transcription factor 2. (323 aa)
S1PR5Sphingosine-1-phosphate receptor 5; Belongs to the G-protein coupled receptor 1 family. (398 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (239 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
FOXG1Forkhead box G1. (490 aa)
ADRA2BAdrenoceptor alpha 2B. (447 aa)
FERD3LFer3 like bHLH transcription factor. (166 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
GLI3GLI family zinc finger 3. (1459 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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