STRINGSTRING
PIGH PIGH PI4K2A PI4K2A MTMR4 MTMR4 DGKE DGKE SLC27A1 SLC27A1 PIK3R2 PIK3R2 ENSCSAP00000001596 ENSCSAP00000001596 GALR2 GALR2 PIK3C2A PIK3C2A PIP4K2C PIP4K2C INPP5F INPP5F INPP5A INPP5A CDS1 CDS1 VAC14 VAC14 PYURF PYURF PGAP2 PGAP2 INPPL1 INPPL1 UVRAG UVRAG SOCS2 SOCS2 ITPKC ITPKC INPP5D INPP5D MTMR10 MTMR10 SH3YL1 SH3YL1 PTEN PTEN PLCB3 PLCB3 MTMR1 MTMR1 MTM1 MTM1 PIGS PIGS IPMK IPMK PLCB2 PLCB2 GPLD1 GPLD1 ITPKA ITPKA SMG1 SMG1 PIK3C2G PIK3C2G PLA2G4E PLA2G4E PLA2G4D PLA2G4D PSORS1C2 PSORS1C2 OCRL OCRL PIP5K1B PIP5K1B PIGP PIGP PIGX PIGX PITPNM1 PITPNM1 PIGZ PIGZ PLA2G3 PLA2G3 PLCD4 PLCD4 GPAA1 GPAA1 INPP5J INPP5J MTMR3 MTMR3 SYNJ1 SYNJ1 IP6K3 IP6K3 PIKFYVE PIKFYVE EFR3A EFR3A PIGO PIGO PIK3R6 PIK3R6 PIK3R4 PIK3R4 MTMR14 MTMR14 FAM126B FAM126B CCDC180 CCDC180 PIP5K1C PIP5K1C PIK3CB PIK3CB LCLAT1 LCLAT1 PIK3CG PIK3CG TTC7B TTC7B PGAP1 PGAP1 C2orf66 C2orf66 PIGB PIGB PDGFRB PDGFRB CSF1R CSF1R MTMR8 MTMR8 PIGU PIGU INPP1 INPP1 PIP4K2A PIP4K2A RGSL1 RGSL1 PITPNM3 PITPNM3 PIGQ PIGQ PIP4P2 PIP4P2 PIK3CA PIK3CA SYNJ2 SYNJ2 IMPA1 IMPA1 PI4KA PI4KA CDIPT CDIPT PIGF PIGF TTC7A TTC7A PLCB1 PLCB1 PIP5KL1 PIP5KL1 FAM126A FAM126A PLCG1 PLCG1 DPM2 DPM2 FAM102A FAM102A INPP5K INPP5K CISH CISH PLCD1 PLCD1 PIGT PIGT PIK3C2B PIK3C2B IMPAD1 IMPAD1 IP6K1 IP6K1 ATG14 ATG14 PLEK PLEK BMX BMX PIGA PIGA PIGG PIGG DPM1 DPM1 LPGAT1 LPGAT1 IP6K2 IP6K2 FIG4 FIG4 BPNT1 BPNT1 INPP5E INPP5E TMEM150A TMEM150A SACM1L SACM1L ITPKB ITPKB PI4K2B PI4K2B LOC103231342 LOC103231342 LOC103231342-2 LOC103231342-2 MTMR7 MTMR7 MTMR9 MTMR9 CWH43 CWH43 INPP4A INPP4A MPPE1 MPPE1 IMPA2 IMPA2 PIK3C3 PIK3C3 ENSCSAP00000013983 ENSCSAP00000013983 MTMR6 MTMR6 MTMR11 MTMR11 PIGN PIGN INPP4B INPP4B PLCG2 PLCG2 MTMR2 MTMR2 ATM ATM PGAP3 PGAP3 PIP4K2B PIP4K2B SOCS7 SOCS7 PITPNM2 PITPNM2 MBOAT7 MBOAT7 PI4KB PI4KB PIP5K1A PIP5K1A FAM102B FAM102B PIGK PIGK PIK3R3 PIK3R3 INPP5B INPP5B PIGV PIGV PIK3CD PIK3CD PLCH2 PLCH2 PIGW PIGW PGAP4 PGAP4 PIGC PIGC PIGM PIGM DPM3 DPM3 SOCS1 SOCS1 SOCS3 SOCS3 SOCS5 SOCS5 SOCS6 SOCS6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIGHPhosphatidylinositol glycan anchor biosynthesis class H. (184 aa)
PI4K2APhosphatidylinositol 4-kinase type 2 alpha. (482 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
DGKEDiacylglycerol kinase. (567 aa)
SLC27A1Solute carrier family 27 member 1. (651 aa)
PIK3R2Uncharacterized protein. (629 aa)
ENSCSAP00000001596Uncharacterized protein. (292 aa)
GALR2Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family. (387 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1689 aa)
PIP4K2CPhosphatidylinositol-5-phosphate 4-kinase type 2 gamma. (421 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (389 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
VAC14VAC14 component of PIKFYVE complex. (782 aa)
PYURFPIGY upstream reading frame. (114 aa)
PGAP2Post-GPI attachment to proteins 2. (254 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
UVRAGUV radiation resistance associated. (699 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1188 aa)
MTMR10Myotubularin related protein 10. (775 aa)
SH3YL1SH3 and SYLF domain containing 1. (342 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
MTMR1Myotubularin related protein 1. (571 aa)
MTM1Myotubularin 1. (548 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (547 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (419 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (638 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (289 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3274 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1506 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (825 aa)
PSORS1C2Psoriasis susceptibility 1 candidate 2. (136 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (884 aa)
PIP5K1BPhosphatidylinositol-4-phosphate 5-kinase type 1 beta. (502 aa)
PIGPPhosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (134 aa)
PIGXPhosphatidylinositol glycan anchor biosynthesis class X. (256 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1244 aa)
PIGZMannosyltransferase. (579 aa)
PLA2G3Phospholipase A2 group III. (509 aa)
PLCD4Phosphoinositide phospholipase C. (766 aa)
GPAA1Glycosylphosphatidylinositol anchor attachment 1. (621 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1001 aa)
MTMR3Myotubularin related protein 3. (1207 aa)
SYNJ1Synaptojanin 1. (1311 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (410 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
EFR3AEFR3 homolog A. (821 aa)
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1089 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (749 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
MTMR14Myotubularin related protein 14. (650 aa)
FAM126BFamily with sequence similarity 126 member B. (586 aa)
CCDC180Coiled-coil domain containing 180. (1621 aa)
PIP5K1CPhosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (668 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
LCLAT1Lysocardiolipin acyltransferase 1. (376 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
TTC7BTetratricopeptide repeat domain 7B. (881 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
C2orf66Chromosome 2 open reading frame 66. (113 aa)
PIGBMannosyltransferase. (557 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
MTMR8Myotubularin related protein 8. (713 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U. (435 aa)
INPP1Inositol polyphosphate-1-phosphatase. (399 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
RGSL1Regulator of G protein signaling like 1. (1063 aa)
PITPNM3PITPNM family member 3. (922 aa)
PIGQPhosphatidylinositol glycan anchor biosynthesis class Q. (581 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SYNJ2Synaptojanin 2. (1496 aa)
IMPA1Inositol-1-monophosphatase. (277 aa)
PI4KAPhosphatidylinositol 4-kinase alpha; Belongs to the PI3/PI4-kinase family. (2044 aa)
CDIPTUncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (430 aa)
PIGFPhosphatidylinositol glycan anchor biosynthesis class F. (219 aa)
TTC7ATetratricopeptide repeat domain 7A. (858 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PIP5KL1Phosphatidylinositol-4-phosphate 5-kinase like 1. (394 aa)
FAM126AFamily with sequence similarity 126 member A. (521 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
DPM2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa)
FAM102AFamily with sequence similarity 102 member A. (384 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (448 aa)
CISHCytokine inducible SH2 containing protein. (264 aa)
PLCD1Phosphoinositide phospholipase C. (756 aa)
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (578 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
ATG14Autophagy related 14. (492 aa)
PLEKPleckstrin. (350 aa)
BMXTyrosine-protein kinase. (677 aa)
PIGAPhosphatidylinositol glycan anchor biosynthesis class A. (484 aa)
PIGGPhosphatidylinositol glycan anchor biosynthesis class G. (894 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (241 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (370 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (426 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (907 aa)
BPNT13'(2'), 5'-bisphosphate nucleotidase 1. (308 aa)
INPP5EInositol polyphosphate-5-phosphatase E. (644 aa)
TMEM150ATransmembrane protein 150A. (271 aa)
SACM1LSAC1 like phosphatidylinositide phosphatase. (587 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (947 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2 beta. (481 aa)
LOC103231342Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa)
LOC103231342-2Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase. (284 aa)
MTMR7Myotubularin related protein 7. (660 aa)
MTMR9Myotubularin related protein 9. (549 aa)
CWH43Cell wall biogenesis 43 C-terminal homolog. (706 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (915 aa)
MPPE1Metallophosphoesterase 1. (396 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
ENSCSAP00000013983Uncharacterized protein. (60 aa)
MTMR6Myotubularin related protein 6. (659 aa)
MTMR11Myotubularin related protein 11. (709 aa)
PIGNPhosphatidylinositol glycan anchor biosynthesis class N. (931 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (881 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
MTMR2Myotubularin related protein 2. (643 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (320 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (352 aa)
SOCS7Suppressor of cytokine signaling 7. (581 aa)
PITPNM2Phosphatidylinositol transfer protein membrane associated 2. (1292 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (343 aa)
PI4KBPhosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (801 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (425 aa)
FAM102BFamily with sequence similarity 102 member B. (360 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (395 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (992 aa)
PIGVGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (493 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PLCH2Phosphoinositide phospholipase C. (944 aa)
PIGWPhosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (504 aa)
PGAP4Transmembrane protein 246. (403 aa)
PIGCPhosphatidylinositol glycan anchor biosynthesis class C. (297 aa)
PIGMGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (423 aa)
DPM3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (121 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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