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ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) | ||||
TERF2IP | TERF2 interacting protein. (400 aa) | ||||
RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
ACD | ACD shelterin complex subunit and telomerase recruitment factor. (537 aa) | ||||
RNF169 | Ring finger protein 169. (486 aa) | ||||
TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (500 aa) | ||||
HELB | DNA helicase B. (1087 aa) | ||||
ENSCSAP00000000740 | Uncharacterized protein. (88 aa) | ||||
RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) | ||||
TEN1 | Uncharacterized protein. (94 aa) | ||||
TIMELESS | Timeless circadian regulator. (1208 aa) | ||||
TENT4B | Terminal nucleotidyltransferase 4B. (635 aa) | ||||
NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa) | ||||
ANKLE1 | Ankyrin repeat and LEM domain containing 1. (615 aa) | ||||
MCRS1 | Microspherule protein 1. (462 aa) | ||||
SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) | ||||
LIG3 | DNA ligase. (1009 aa) | ||||
TNKS2 | Poly [ADP-ribose] polymerase. (1166 aa) | ||||
NPPC | Natriuretic peptide C. (126 aa) | ||||
ANKRD1 | Ankyrin repeat domain 1. (319 aa) | ||||
OTUB1 | Ubiquitin thioesterase. (280 aa) | ||||
TRIP12 | Thyroid hormone receptor interactor 12. (2067 aa) | ||||
POLQ | DNA polymerase theta. (2729 aa) | ||||
MEN1 | Menin 1. (610 aa) | ||||
GMNN | Geminin DNA replication inhibitor. (209 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (735 aa) | ||||
NRM | Nurim. (262 aa) | ||||
RMI2 | RecQ mediated genome instability 2. (147 aa) | ||||
FLCN | Folliculin. (579 aa) | ||||
HSF1 | Heat shock transcription factor 1. (529 aa) | ||||
CDAN1 | Codanin 1. (1228 aa) | ||||
GMNC | Geminin coiled-coil domain containing. (334 aa) | ||||
NUDT16L1 | Nudix hydrolase 16 like 1. (225 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (949 aa) | ||||
XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) | ||||
H1-8 | H1 histone family member O oocyte specific. (346 aa) | ||||
BCL6 | BCL6 transcription repressor. (708 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1977 aa) | ||||
CYREN | Cell cycle regulator of NHEJ. (159 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (275 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (806 aa) | ||||
RADX | RPA1 related single stranded DNA binding protein, X-linked. (855 aa) | ||||
WAPL | WAPL cohesin release factor. (1190 aa) | ||||
DONSON | Downstream neighbor of SON. (564 aa) | ||||
SHLD2 | FAM35_C domain-containing protein. (856 aa) | ||||
SLX4 | Uncharacterized protein. (929 aa) | ||||
GDF2 | Growth differentiation factor 2. (429 aa) | ||||
POT1 | Protection of telomeres 1. (634 aa) | ||||
CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1494 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) | ||||
OGG1 | 8-oxoguanine DNA glycosylase. (405 aa) | ||||
CTC1 | CST telomere replication complex component 1. (1209 aa) | ||||
OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (243 aa) | ||||
ENSCSAP00000007206 | Uncharacterized protein. (119 aa) | ||||
XRN1 | 5'-3' exoribonuclease 1. (1707 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) | ||||
ENSCSAP00000007796 | H15 domain-containing protein. (342 aa) | ||||
DNAJC2 | DnaJ heat shock protein family (Hsp40) member C2. (621 aa) | ||||
UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2793 aa) | ||||
GNL3L | G protein nucleolar 3 like. (472 aa) | ||||
NDFIP1 | Nedd4 family interacting protein 1. (221 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa) | ||||
TSPYL2 | TSPY like 2; Belongs to the nucleosome assembly protein (NAP) family. (696 aa) | ||||
FOXP3 | Forkhead box P3. (358 aa) | ||||
TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa) | ||||
GATA3 | GATA binding protein 3. (443 aa) | ||||
SHLD1 | Shieldin complex subunit 1. (205 aa) | ||||
FBXO5 | F-box protein 5. (448 aa) | ||||
MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa) | ||||
MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (440 aa) | ||||
FBH1 | F-box DNA helicase 1. (971 aa) | ||||
SRC | Tyrosine-protein kinase. (633 aa) | ||||
NIBAN2 | Niban apoptosis regulator 2. (746 aa) | ||||
SMG6 | SMG6 nonsense mediated mRNA decay factor. (1419 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (532 aa) | ||||
CGAS | Cyclic GMP-AMP synthase. (526 aa) | ||||
GTPBP4 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa) | ||||
PML | Promyelocytic leukemia. (819 aa) | ||||
MLH1 | MutL homolog 1. (756 aa) | ||||
KLHL15 | Kelch like family member 15. (604 aa) | ||||
XRCC4 | X-ray repair cross complementing 4. (334 aa) | ||||
DCP2 | Decapping mRNA 2. (420 aa) | ||||
TTF1 | Transcription termination factor 1. (916 aa) | ||||
MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1125 aa) | ||||
FANCB | FA complementation group B. (859 aa) | ||||
KCNK2 | Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa) | ||||
ENSCSAP00000011749 | G-patch domain-containing protein. (330 aa) | ||||
TINF2 | TERF1 interacting nuclear factor 2. (424 aa) | ||||
RIF1 | Replication timing regulatory factor 1. (2465 aa) | ||||
PARP1 | Poly(ADP-ribose) polymerase 1. (709 aa) | ||||
ZRANB3 | Zinc finger RANBP2-type containing 3. (1016 aa) | ||||
MCIDAS | Multiciliate differentiation and DNA synthesis associated cell cycle protein. (385 aa) | ||||
HNRNPC | Heterogeneous nuclear ribonucleoprotein C (C1/C2). (293 aa) | ||||
GZMA | Granzyme A; Belongs to the peptidase S1 family. (262 aa) | ||||
TNKS | Poly [ADP-ribose] polymerase. (1327 aa) | ||||
PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (328 aa) | ||||
PDS5A | PDS5 cohesin associated factor A. (1293 aa) | ||||
BLM | BLM RecQ like helicase. (1423 aa) | ||||
SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (2005 aa) | ||||
DACH1 | Dachshund family transcription factor 1. (454 aa) | ||||
THOC1 | THO complex 1. (657 aa) | ||||
BRCA2 | BRCA2 DNA repair associated. (3420 aa) | ||||
PARPBP | PARP1 binding protein. (581 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) | ||||
HCRT | Orexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa) | ||||
ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) | ||||
CDT1 | Chromatin licensing and DNA replication factor 1. (551 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa) | ||||
CHEK1 | Checkpoint kinase 1. (749 aa) | ||||
UBQLN4 | Ubiquitin-like domain-containing protein. (308 aa) | ||||
TRIM28 | Tripartite motif containing 28. (834 aa) | ||||
AUNIP | Aurora kinase A and ninein interacting protein. (351 aa) | ||||
MAD2L2 | Mitotic arrest deficient 2 like 2. (211 aa) | ||||
EXOSC10 | Exosome component 10. (884 aa) | ||||
DFFA | DNA fragmentation factor subunit alpha. (331 aa) | ||||
HNRNPCL1 | RRM domain-containing protein. (293 aa) | ||||
ZNF830 | Zinc finger protein 830. (372 aa) | ||||
S100A11 | Protein S100; Belongs to the S-100 family. (105 aa) | ||||
H1-10 | H1 histone family member X. (213 aa) | ||||
MAGEF1 | MAGE family member F1. (308 aa) | ||||
H1-5 | Histone cluster 1 H1 family member b. (226 aa) | ||||
H1-3 | Histone cluster 1 H1 family member d. (221 aa) | ||||
H1-4 | Histone cluster 1 H1 family member e. (219 aa) | ||||
H1-6 | Histone cluster 1 H1 family member t. (208 aa) | ||||
H1-2 | Histone cluster 1 H1 family member c. (213 aa) | ||||
H1-1 | Histone cluster 1 H1 family member a. (215 aa) | ||||
ENSCSAP00000018936 | Protein S100; Belongs to the S-100 family. (105 aa) | ||||
ENSCSAP00000018998 | Protein S100; Belongs to the S-100 family. (101 aa) | ||||
ENSCSAP00000019103 | EF-hand domain-containing protein; Belongs to the S-100 family. (104 aa) |