STRINGSTRING
FOXP1 FOXP1 NFATC3 NFATC3 ENSCSAP00000000421 ENSCSAP00000000421 FRS2 FRS2 EREG EREG SOX6 SOX6 ANKRD17 ANKRD17 PDCD4 PDCD4 PPARA PPARA TRIM72 TRIM72 HDAC4 HDAC4 TOMM70 TOMM70 PDGFB PDGFB SHH SHH G6PD G6PD MECP2 MECP2 EZH2 EZH2 DKK1 DKK1 DNMT1 DNMT1 BHLHE41 BHLHE41 MYOCD MYOCD NKX2-5 NKX2-5 TCF23 TCF23 BMPR1A BMPR1A IGF2 IGF2 XBP1 XBP1 PI16 PI16 BMPR2 BMPR2 CAV3 CAV3 CCN3 CCN3 FOXO4 FOXO4 DLL1 DLL1 RBPMS2 RBPMS2 PTBP1 PTBP1 RGS2 RGS2 BMP2 BMP2 PRDM6 PRDM6 PLPP7 PLPP7 NFATC2 NFATC2 CCDC142 CCDC142 NOTCH1 NOTCH1 MSX1 MSX1 HEY2 HEY2 FGF9 FGF9 SMAD4 SMAD4 NFATC1 NFATC1 CTDP1 CTDP1 GSK3A GSK3A SMAD1 SMAD1 YBX1 YBX1 ZBED6 ZBED6 FZD7 FZD7 TMEM119 TMEM119 BHLHA15 BHLHA15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXP1Fork-head domain-containing protein. (677 aa)
NFATC3RHD domain-containing protein. (637 aa)
ENSCSAP00000000421Uncharacterized protein. (398 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
EREGEpiregulin. (171 aa)
SOX6SRY-box transcription factor 6. (466 aa)
ANKRD17Ankyrin repeat domain 17. (2490 aa)
PDCD4Programmed cell death 4. (469 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
TRIM72Tripartite motif containing 72. (348 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1088 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (479 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
MYOCDMyocardin. (986 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TCF23Transcription factor 23. (214 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
IGF2Insulin like growth factor 2. (236 aa)
XBP1X-box binding protein 1. (261 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (460 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
CCN3Cellular communication network factor 3. (357 aa)
FOXO4Forkhead box O4. (505 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (217 aa)
PTBP1Polypyrimidine tract binding protein 1. (556 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
PRDM6PR/SET domain 6. (597 aa)
PLPP7Phospholipid phosphatase 7 (inactive). (271 aa)
NFATC2Nuclear factor of activated T cells 2. (928 aa)
CCDC142Coiled-coil domain containing 142. (750 aa)
NOTCH1Notch receptor 1. (2555 aa)
MSX1Msh homeobox 1. (303 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (864 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
YBX1Y-box binding protein 1. (255 aa)
ZBED6Zinc finger BED-type containing 6. (977 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
TMEM119Transmembrane protein 119. (280 aa)
BHLHA15Basic helix-loop-helix family member a15. (194 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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