STRINGSTRING
NKX2-5 NKX2-5 ACTN2 ACTN2 MYO18B MYO18B SGCD SGCD CAV3 CAV3 ASB2 ASB2 SRF SRF PDGFRB PDGFRB SHOX2 SHOX2 SLC8A1 SLC8A1 C10orf113 C10orf113 NEBL NEBL TTN TTN JAG1 JAG1 BVES BVES ATG5 ATG5 BMP10 BMP10 PROX1 PROX1 NOTCH1 NOTCH1 ADRA1A ADRA1A NEB NEB NKX2-6 NKX2-6 HEY2 HEY2 ISL1 ISL1 MEF2A MEF2A GATA4 GATA4 FHL2 FHL2 AKAP13 AKAP13 ALPK3 ALPK3 TBX18 TBX18 FHOD3 FHOD3 ALPK2 ALPK2 SORBS2 SORBS2 TCAP TCAP MYL2 MYL2 TBX5 TBX5 TBX3 TBX3 LMNA LMNA TGFBR3 TGFBR3 ZMPSTE24 ZMPSTE24 MTOR MTOR SPRY1 SPRY1 LRRC10 LRRC10 ENSCSAP00000013468 ENSCSAP00000013468 MAML1 MAML1 MYH11 MYH11 OBSL1 OBSL1 NRAP NRAP CSRP3 CSRP3 SGCB SGCB PDLIM5 PDLIM5 PLEC PLEC CXADR CXADR MAP2K4 MAP2K4 HNRNPU HNRNPU BMPR1A BMPR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX2-5NK2 homeobox 5. (324 aa)
ACTN2Actinin alpha 2. (894 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2208 aa)
SGCDSarcoglycan delta. (224 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
SRFSerum response factor. (508 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
SHOX2Short stature homeobox 2. (331 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (632 aa)
C10orf113Chromosome 10 open reading frame 113. (155 aa)
NEBLNebulette. (716 aa)
TTNTitin. (32000 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
BVESBlood vessel epicardial substance. (360 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
PROX1Prospero homeobox 1. (737 aa)
NOTCH1Notch receptor 1. (2555 aa)
ADRA1AAdrenoceptor alpha 1A. (425 aa)
NEBNebulin. (5297 aa)
NKX2-6NK2 homeobox 6. (301 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ISL1ISL LIM homeobox 1. (349 aa)
MEF2AMyocyte enhancer factor 2A. (503 aa)
GATA4GATA binding protein 4. (442 aa)
FHL2Four and a half LIM domains 2. (279 aa)
AKAP13A-kinase anchoring protein 13. (2854 aa)
ALPK3Alpha kinase 3. (1701 aa)
TBX18T-box transcription factor 18. (607 aa)
FHOD3Formin homology 2 domain containing 3. (1622 aa)
ALPK2Alpha kinase 2. (2166 aa)
SORBS2Sorbin and SH3 domain containing 2. (1524 aa)
TCAPTitin-cap. (167 aa)
MYL2Myosin light chain 2. (166 aa)
TBX5T-box transcription factor 5. (518 aa)
TBX3T-box transcription factor 3. (723 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
LRRC10Leucine rich repeat containing 10. (279 aa)
ENSCSAP00000013468Uncharacterized protein. (1924 aa)
MAML1Mastermind like transcriptional coactivator 1. (790 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1953 aa)
OBSL1Obscurin like 1. (1896 aa)
NRAPNebulin related anchoring protein. (1042 aa)
CSRP3Cysteine and glycine rich protein 3. (194 aa)
SGCBSarcoglycan beta. (297 aa)
PDLIM5PDZ and LIM domain 5. (546 aa)
PLECPlectin. (4605 aa)
CXADRCXADR Ig-like cell adhesion molecule. (352 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (806 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.