STRINGSTRING
SMAD4 SMAD4 EDNRA EDNRA ZFPM1 ZFPM1 TCAP TCAP MED1 MED1 MYL2 MYL2 TNNI3 TNNI3 COL11A1 COL11A1 TGFBR3 TGFBR3 NOG NOG S1PR1 S1PR1 FOXC2 FOXC2 FOXC1 FOXC1 TNNC1 TNNC1 BMP2 BMP2 ENG ENG TNNT2 TNNT2 TNNI1 TNNI1 CHD7 CHD7 TBX20 TBX20 BMP10 BMP10 LRP2 LRP2 XIRP2 XIRP2 PROX1 PROX1 PTCD2 PTCD2 TGFB2 TGFB2 NRG1 NRG1 NOTCH1 NOTCH1 MYH7 MYH7 MYH6 MYH6 MYL3 MYL3 HEY2 HEY2 ISL1 ISL1 SMAD7 SMAD7 MYL10 MYL10 TGFB1 TGFB1 FGFR2 FGFR2 MYBPC3 MYBPC3 ANKRD1 ANKRD1 PKP2 PKP2 DSP DSP DLL4 DLL4 HEG1 HEG1 FOXH1 FOXH1 NKX2-5 NKX2-5 RYR2 RYR2 BMPR1A BMPR1A EGLN1 EGLN1 HAND1 HAND1 WNT2 WNT2 TGFBR1 TGFBR1 ZFPM2 ZFPM2 MYLK2 MYLK2 WNT5A WNT5A TTN TTN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD4Mothers against decapentaplegic homolog. (552 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
TCAPTitin-cap. (167 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
MYL2Myosin light chain 2. (166 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
COL11A1Collagen type XI alpha 1 chain. (1806 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
FOXC2Forkhead box C2. (501 aa)
FOXC1Forkhead box C1. (552 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ENGEndoglin. (658 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
TNNI1Troponin I1, slow skeletal type. (183 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
TBX20T-box transcription factor 20. (447 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
LRP2LDL receptor related protein 2. (3861 aa)
XIRP2Xin actin binding repeat containing 2. (3378 aa)
PROX1Prospero homeobox 1. (737 aa)
PTCD2Pentatricopeptide repeat domain 2. (383 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
NRG1Neuregulin 1. (467 aa)
NOTCH1Notch receptor 1. (2555 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1501 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
MYL3Myosin light chain 3. (197 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
MYL10Myosin light chain 10. (136 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
MYBPC3Myosin binding protein C, cardiac. (1266 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
PKP2Plakophilin 2. (837 aa)
DSPDesmoplakin. (2871 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
HEG1Heart development protein with EGF like domains 1. (1323 aa)
FOXH1Forkhead box H1. (365 aa)
NKX2-5NK2 homeobox 5. (324 aa)
RYR2Ryanodine receptor 2. (4906 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (426 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
ZFPM2Zinc finger protein, FOG family member 2. (940 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
TTNTitin. (32000 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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