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SLC25A28 SLC25A28 ENSCSAP00000019100 ENSCSAP00000019100 FTHL17 FTHL17 BOLA1 BOLA1 ENSCSAP00000017573 ENSCSAP00000017573 FTMT FTMT ATP13A2 ATP13A2 FRRS1 FRRS1 HJV HJV ATP6V0A2 ATP6V0A2 FTL FTL ISCU ISCU HEPHL1 HEPHL1 SMAD4 SMAD4 TFR2 TFR2 ATP6AP1 ATP6AP1 CCDC115 CCDC115 STEAP3 STEAP3 SLC39A14 SLC39A14 FBXL5 FBXL5 LTF LTF SLC25A37 SLC25A37 SLC22A17 SLC22A17 SCARA5 SCARA5 FLVCR1 FLVCR1 IREB2 IREB2 ENSCSAP00000010995 ENSCSAP00000010995 CYBRD1 CYBRD1 ENSCSAP00000010398 ENSCSAP00000010398 HYAL2 HYAL2 HIF1A HIF1A LCN2 LCN2 NEO1 NEO1 TTC7A TTC7A EPAS1 EPAS1 ATP6V1G1 ATP6V1G1 RHAG RHAG STEAP2 STEAP2 STEAP1 STEAP1 STEAP4 STEAP4 SLC40A1 SLC40A1 NDFIP1 NDFIP1 HEPH HEPH CP CP ABCB7 ABCB7 TF TF GLRX5 GLRX5 BTBD9 BTBD9 NCOA4 NCOA4 EGLN1 EGLN1 MYC MYC GDF2 GDF2 ACO1 ACO1 B2M B2M EPB42 EPB42 SLC11A1 SLC11A1 MELTF MELTF TFRC TFRC FXN FXN NUBP1 NUBP1 ABCB6 ABCB6 HMOX1 HMOX1 HFE HFE TMPRSS6 TMPRSS6 BMP6 BMP6 TMEM199 TMEM199 SLC46A1 SLC46A1 ATP6V1A ATP6V1A FTH1 FTH1 CYB561A3 CYB561A3 BOLA2B BOLA2B ERFE ERFE SLC11A2 SLC11A2 HAMP HAMP GLRX3 GLRX3 HPX HPX SLC39A8 SLC39A8 BDH2 BDH2 ATP6V0D1 ATP6V0D1 CYB561 CYB561 PICALM PICALM
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SLC25A28Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (364 aa)
ENSCSAP00000019100Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
FTHL17Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
BOLA1BolA family member 1; Belongs to the BolA/IbaG family. (137 aa)
ENSCSAP00000017573Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (165 aa)
FTMTFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (243 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa)
FRRS1Ferric chelate reductase 1. (598 aa)
HJVHemojuvelin BMP co-receptor. (425 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (856 aa)
FTLFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (175 aa)
ISCUIron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
HEPHL1Hephaestin like 1; Belongs to the multicopper oxidase family. (1160 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TFR2Transferrin receptor 2. (798 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (475 aa)
CCDC115Coiled-coil domain containing 115. (209 aa)
STEAP3STEAP3 metalloreductase. (488 aa)
SLC39A14Solute carrier family 39 member 14. (342 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
SLC25A37Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
SLC22A17Solute carrier family 22 member 17. (366 aa)
SCARA5Scavenger receptor class A member 5; Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non- transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the de [...] (495 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
IREB2Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa)
ENSCSAP00000010995V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
CYBRD1Cytochrome b reductase 1. (286 aa)
ENSCSAP00000010398Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (179 aa)
HYAL2Hyaluronidase. (473 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
LCN2Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (199 aa)
NEO1Neogenin 1. (1465 aa)
TTC7ATetratricopeptide repeat domain 7A. (858 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
RHAGRh associated glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (428 aa)
STEAP2STEAP2 metalloreductase. (358 aa)
STEAP1Ferric oxidoreductase domain-containing protein. (339 aa)
STEAP4STEAP4 metalloreductase. (459 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
HEPHHephaestin; Belongs to the multicopper oxidase family. (1212 aa)
CPCeruloplasmin; Belongs to the multicopper oxidase family. (1090 aa)
ABCB7ATP binding cassette subfamily B member 7. (698 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
GLRX5Glutaredoxin 5. (157 aa)
BTBD9BTB domain containing 9. (385 aa)
NCOA4Nuclear receptor coactivator 4. (615 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (426 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
GDF2Growth differentiation factor 2. (429 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (895 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
EPB42Erythrocyte membrane protein band 4.2. (722 aa)
SLC11A1Solute carrier family 11 member 1. (550 aa)
MELTFMelanotransferrin; Belongs to the transferrin family. (733 aa)
TFRCTransferrin receptor. (774 aa)
FXNFrataxin. (210 aa)
NUBP1Nucleotide binding protein 1. (271 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (843 aa)
HMOX1Heme oxygenase 1. (288 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (300 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
TMEM199Transmembrane protein 199. (208 aa)
SLC46A1Solute carrier family 46 member 1. (459 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (182 aa)
CYB561A3Cytochrome b561 family member A3. (245 aa)
BOLA2BUncharacterized protein; Belongs to the BolA/IbaG family. (152 aa)
ERFEErythroferrone. (353 aa)
SLC11A2Solute carrier family 11 member 2. (572 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
GLRX3Glutaredoxin 3. (335 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
SLC39A8Solute carrier family 39 member 8. (460 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (230 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
CYB561Cytochrome b561. (251 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (660 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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