STRINGSTRING
LOC103243499 LOC103243499 SERPINH1 SERPINH1 SMPD3 SMPD3 AXIN2 AXIN2 BMPR1B BMPR1B INPPL1 INPPL1 SOX9 SOX9 SCUBE2 SCUBE2 GLG1 GLG1 FGFR2 FGFR2 NAB2 NAB2 COL1A1 COL1A1 COMP COMP RARG RARG EXT2 EXT2 COL2A1 COL2A1 INSIG1 INSIG1 NPPC NPPC ACP5 ACP5 ATG9B ATG9B ENSCSAP00000003372 ENSCSAP00000003372 BMP6 BMP6 TFAP2A TFAP2A LTBP3 LTBP3 COL13A1 COL13A1 ATG9A ATG9A ACTN3 ACTN3 IHH IHH SCX SCX LRP5 LRP5 CER1 CER1 FREM1 FREM1 FGF4 FGF4 ENSCSAP00000005806 ENSCSAP00000005806 TGFBR2 TGFBR2 FGF18 FGF18 RARB RARB BMPR2 BMPR2 HAS2 HAS2 TMEM107 TMEM107 EXT1 EXT1 ANXA6 ANXA6 PAX1 PAX1 IFITM5 IFITM5 TRIP11 TRIP11 FOXN3 FOXN3 CDX1 CDX1 TGFB3 TGFB3 SHOX2 SHOX2 TBXT TBXT NAB1 NAB1 IFT80 IFT80 OSR2 OSR2 COL3A1 COL3A1 RUNX2 RUNX2 COL27A1 COL27A1 MMP16 MMP16 DLX5 DLX5 TIFAB TIFAB RAB23 RAB23 HOXA11 HOXA11 HOXD11 HOXD11 ATF2 ATF2 IMPAD1 IMPAD1 MEF2C MEF2C BMP4 BMP4 SP5 SP5 SFRP4 SFRP4 CYP26B1 CYP26B1 GLI3 GLI3 FGFR3 FGFR3 STC1 STC1 LTF LTF MMP14 MMP14 MSX1 MSX1 CHSY1 CHSY1 PEX7 PEX7 RIPPLY2 RIPPLY2 TGFB1 TGFB1 MEGF8 MEGF8 MMP13 MMP13 RARA RARA TRPV4 TRPV4 PHOSPHO1 PHOSPHO1 MEF2D MEF2D THBS3 THBS3 ZMPSTE24 ZMPSTE24 MATN1 MATN1 ALPL ALPL DHRS3 DHRS3 SKI SKI TSKU TSKU NEUROG1 NEUROG1 CITED2 CITED2 PHOSPHO2 PHOSPHO2 TMEM119 TMEM119 FOXC1 FOXC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103243499Uncharacterized protein. (251 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (418 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
AXIN2Axin 2. (843 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1258 aa)
SOX9SRY-box transcription factor 9. (509 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (944 aa)
GLG1Golgi glycoprotein 1. (1051 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
NAB2NGFI-A binding protein 2. (442 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
RARGRetinoic acid receptor gamma. (443 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (751 aa)
COL2A1Collagen type II alpha 1 chain. (1488 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
NPPCNatriuretic peptide C. (126 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
ENSCSAP00000003372Uncharacterized protein. (478 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
TFAP2ATranscription factor AP-2 alpha. (318 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
COL13A1Collagen type XIII alpha 1 chain. (759 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
LRP5LDL receptor related protein 5. (1451 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
FREM1FRAS1 related extracellular matrix 1. (1178 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
ENSCSAP00000005806Fork-head domain-containing protein. (481 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
RARBRetinoic acid receptor beta. (448 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
HAS2Hyaluronan synthase 2. (552 aa)
TMEM107Transmembrane protein 107. (146 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (420 aa)
ANXA6Annexin. (676 aa)
PAX1Paired box 1. (399 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
TRIP11Thyroid hormone receptor interactor 11. (1700 aa)
FOXN3Forkhead box N3. (368 aa)
CDX1Caudal type homeobox 1. (265 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SHOX2Short stature homeobox 2. (331 aa)
TBXTT-box transcription factor T. (436 aa)
NAB1NGFI-A binding protein 1. (488 aa)
IFT80Intraflagellar transport 80. (768 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
COL3A1Collagen type III alpha 1 chain. (878 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (450 aa)
COL27A1Collagen type XXVII alpha 1 chain. (1860 aa)
MMP16Matrix metallopeptidase 16. (607 aa)
DLX5Distal-less homeobox 5. (289 aa)
TIFABTIFA inhibitor. (161 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
HOXA11Homeobox A11. (310 aa)
HOXD11Homeobox D11. (338 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SP5Sp5 transcription factor. (398 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa)
GLI3GLI family zinc finger 3. (1459 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
STC1Stanniocalcin 1. (247 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
MSX1Msh homeobox 1. (303 aa)
CHSY1Hexosyltransferase. (711 aa)
PEX7Peroxisomal biogenesis factor 7. (289 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MEGF8Multiple EGF like domains 8. (2789 aa)
MMP13Matrix metallopeptidase 13. (471 aa)
RARARetinoic acid receptor alpha. (462 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (824 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
THBS3Thrombospondin 3. (947 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
MATN1Matrilin 1. (496 aa)
ALPLAlkaline phosphatase. (524 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
SKISKI proto-oncogene. (728 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
NEUROG1Neurogenin 1. (237 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
TMEM119Transmembrane protein 119. (280 aa)
FOXC1Forkhead box C1. (552 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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