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SLC40A1 SLC40A1 COL1A1 COL1A1 MMP2 MMP2 WNT10B WNT10B SEMA4D SEMA4D DLL4 DLL4 HEG1 HEG1 FOXH1 FOXH1 ADAMTS1 ADAMTS1 NKX2-5 NKX2-5 BMPR1A BMPR1A TEK TEK EGLN1 EGLN1 CAV3 CAV3 TGFBR1 TGFBR1 OVOL2 OVOL2 SRF SRF PPARGC1B PPARGC1B SBNO2 SBNO2 SOS1 SOS1 BMP5 BMP5 HEY1 HEY1 ENG ENG FBN2 FBN2 CHD7 CHD7 BMP10 BMP10 RHOA RHOA SFRP1 SFRP1 BMP7 BMP7 TGFB2 TGFB2 NRG1 NRG1 PLXNB1 PLXNB1 NOTCH1 NOTCH1 HEY2 HEY2 ADGRG6 ADGRG6 FHL2 FHL2 MED1 MED1 THBS3 THBS3 TGFBR3 TGFBR3 NOG NOG S1PR1 S1PR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (573 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
HEG1Heart development protein with EGF like domains 1. (1323 aa)
FOXH1Forkhead box H1. (365 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
NKX2-5NK2 homeobox 5. (324 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (426 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
SRFSerum response factor. (508 aa)
PPARGC1BPPARG coactivator 1 beta. (996 aa)
SBNO2Strawberry notch homolog 2. (1366 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
ENGEndoglin. (658 aa)
FBN2Fibrillin 2. (2916 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
RHOARas homolog family member A. (193 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
NRG1Neuregulin 1. (467 aa)
PLXNB1Plexin B1. (2140 aa)
NOTCH1Notch receptor 1. (2555 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ADGRG6Adhesion G protein-coupled receptor G6; Belongs to the G-protein coupled receptor 2 family. (1220 aa)
FHL2Four and a half LIM domains 2. (279 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
THBS3Thrombospondin 3. (947 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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