STRINGSTRING
ROCK2 ROCK2 GREM1 GREM1 ADRB2 ADRB2 FZD9 FZD9 TMEM119 TMEM119 CEBPB CEBPB PHOSPHO2 PHOSPHO2 S1PR1 S1PR1 ISG15 ISG15 WNT4 WNT4 MATN1 MATN1 ZMPSTE24 ZMPSTE24 CCN1 CCN1 RFLNA RFLNA BGLAP BGLAP NOTUM NOTUM P2RX7 P2RX7 PHOSPHO1 PHOSPHO1 TRPM4 TRPM4 DDR2 DDR2 MMP20 MMP20 TGFB1 TGFB1 LOC103246986 LOC103246986 ECM1 ECM1 KL KL FAM20C FAM20C TENT5A TENT5A GAS6 GAS6 ANKH ANKH ENPP1 ENPP1 HEY2 HEY2 CCR1 CCR1 LTF LTF ACVR2A ACVR2A PTK2B PTK2B ACVR1 ACVR1 NOTCH1 NOTCH1 RXRA RXRA BMP7 BMP7 GPM6B GPM6B BMP4 BMP4 TXLNG TXLNG MEF2C MEF2C ADGRV1 ADGRV1 ACVR2B ACVR2B RFLNB RFLNB AHSG AHSG FBN2 FBN2 HIF1A HIF1A BCOR BCOR FBXO5 FBXO5 BMP2 BMP2 HEY1 HEY1 SMAD3 SMAD3 GATA1 GATA1 PKDCC PKDCC SLC8A1 SLC8A1 OSR2 OSR2 TGFB3 TGFB3 FGF23 FGF23 IFITM5 IFITM5 CFTR CFTR ALOX5 ALOX5 BMPR2 BMPR2 BMPR1A BMPR1A ATRAID ATRAID RXRB RXRB PTN PTN WNT6 WNT6 MGP MGP ACTN3 ACTN3 OSR1 OSR1 LTBP3 LTBP3 SRGN SRGN TFAP2A TFAP2A BMP6 BMP6 OMD OMD ASPN ASPN NOS3 NOS3 ANO6 ANO6 ATF4 ATF4 WNT10B WNT10B COMP COMP NELL1 NELL1 ENSCSAP00000001238 ENSCSAP00000001238 ENAM ENAM C7H4orf26 C7H4orf26 CYP27B1 CYP27B1 BMP2K BMP2K SOX9 SOX9 DMP1 DMP1 BMPR1B BMPR1B SGMS2 SGMS2 ATP2B1 ATP2B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
GREM1Gremlin. (184 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
TMEM119Transmembrane protein 119. (280 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
PHOSPHO2Phosphatase, orphan 2. (241 aa)
S1PR1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
MATN1Matrilin 1. (496 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CCN1Cellular communication network factor 1. (381 aa)
RFLNARefilin A. (216 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (354 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (491 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1214 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
MMP20Matrix metallopeptidase 20. (483 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
LOC103246986Uncharacterized protein. (480 aa)
ECM1Extracellular matrix protein 1. (540 aa)
KLKlotho. (1010 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
TENT5ATerminal nucleotidyltransferase 5A. (442 aa)
GAS6Growth arrest specific 6. (542 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (685 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NOTCH1Notch receptor 1. (2555 aa)
RXRARetinoid X receptor alpha. (462 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
GPM6BGlycoprotein M6B. (330 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TXLNGTaxilin gamma. (524 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
ADGRV1Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family. (6316 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
RFLNBRefilin B. (216 aa)
AHSGAlpha 2-HS glycoprotein. (367 aa)
FBN2Fibrillin 2. (2916 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
BCORBCL6 corepressor. (1721 aa)
FBXO5F-box protein 5. (448 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
GATA1GATA binding protein 1. (414 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (493 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (632 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
IFITM5Interferon induced transmembrane protein 5. (132 aa)
CFTRCFTR_R domain-containing protein. (289 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
RXRBRetinoid X receptor beta. (533 aa)
PTNPleiotrophin. (168 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (103 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
SRGNSerglycin. (153 aa)
TFAP2ATranscription factor AP-2 alpha. (318 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
OMDOsteomodulin. (339 aa)
ASPNAsporin. (374 aa)
NOS3Nitric oxide synthase 3. (867 aa)
ANO6Anoctamin. (910 aa)
ATF4Activating transcription factor 4. (351 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
NELL1Neural EGFL like 1. (810 aa)
ENSCSAP00000001238Uncharacterized protein. (54 aa)
ENAMEnamelin. (1139 aa)
C7H4orf26Uncharacterized protein. (131 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
BMP2KBMP2 inducible kinase. (1106 aa)
SOX9SRY-box transcription factor 9. (509 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (506 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1176 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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