STRINGSTRING
PDE8A PDE8A RAP1A RAP1A ENSCSAP00000016690 ENSCSAP00000016690 HCRTR1 HCRTR1 PLA2G5 PLA2G5 PLA2G2A PLA2G2A PRKCZ PRKCZ P2RY6 P2RY6 TPBGL TPBGL ENSCSAP00000017599 ENSCSAP00000017599 ENSCSAP00000017683 ENSCSAP00000017683 GPR183 GPR183 TPBG TPBG JUN JUN SPRY2 SPRY2 ENSCSAP00000018173 ENSCSAP00000018173 GPBAR1 GPBAR1 ACKR3 ACKR3 GPER1 GPER1 C5AR2 C5AR2 ANGPT1 ANGPT1 CSF1R CSF1R PDGFRB PDGFRB CD74 CD74 NRP1 NRP1 TREM2 TREM2 TNFAIP8L3 TNFAIP8L3 FGF23 FGF23 LOC103230639 LOC103230639 LOC103230637 LOC103230637 HRAS HRAS MIF MIF DDTL DDTL HAVCR2 HAVCR2 GLIPR2 GLIPR2 CD4 CD4 CCL21 CCL21 CCL19 CCL19 PHB2 PHB2 TEK TEK FGF18 FGF18 ENSCSAP00000005731 ENSCSAP00000005731 ERBB4 ERBB4 HLA-DQB1 HLA-DQB1 AGER AGER FGF4 FGF4 FGF19 FGF19 APP APP NELFE NELFE FGFR4 FGFR4 GAREM2 GAREM2 DNAJC27 DNAJC27 NODAL NODAL BRAF BRAF MAP2K7 MAP2K7 ENSCSAP00000004411 ENSCSAP00000004411 FLT4 FLT4 IAPP IAPP GCNT2 GCNT2 CASR CASR RASGRP1 RASGRP1 CCL20 CCL20 VEGFB VEGFB PTEN PTEN ALKAL2 ALKAL2 PRXL2C PRXL2C HTR2B HTR2B FBXW9 FBXW9 PDGFB PDGFB CCL13 CCL13 CCL8 CCL8 CCL1 CCL1 ENSCSAP00000002584 ENSCSAP00000002584 FFAR4 FFAR4 CCL5 CCL5 CCL16 CCL16 CCL14 CCL14 CCL15 CCL15 CCL18 CCL18 ENSCSAP00000002492 ENSCSAP00000002492 MAPK3 MAPK3 ENSCSAP00000002431 ENSCSAP00000002431 PYCARD PYCARD FGF8 FGF8 MAP3K12 MAP3K12 CD44 CD44 NOD2 NOD2 MT3 MT3 KDR KDR CCL22 CCL22 CX3CL1 CX3CL1 CCL17 CCL17 NDRG4 NDRG4 FGFR2 FGFR2 DENND2B DENND2B IL26 IL26 CAVIN3 CAVIN3 PRKCA PRKCA ITGB3 ITGB3 FGF2 FGF2 SRC SRC FSHR FSHR NRXN1 NRXN1 THPO THPO SERPINF2 SERPINF2 GPNMB GPNMB NPTN NPTN SEMA7A SEMA7A AKAP12 AKAP12 CHI3L1 CHI3L1 MTURN MTURN NOD1 NOD1 DSTYK DSTYK ALKAL1 ALKAL1 ABL1 ABL1 BMP4 BMP4 BMPER BMPER FERMT2 FERMT2 F2R F2R GCG GCG FGFR3 FGFR3 RAMP3 RAMP3 SLC30A10 SLC30A10 CARD9 CARD9 NRG1 NRG1 NOTCH1 NOTCH1 PTK2B PTK2B ADRA1A ADRA1A EGFR EGFR CCR1 CCR1 CCN2 CCN2 FGF10 FGF10 FGF20 FGF20 MFHAS1 MFHAS1 GATA4 GATA4 CIB1 CIB1 GAS6 GAS6 PDGFA PDGFA ENSCSAP00000013641 ENSCSAP00000013641 S100A7L2 S100A7L2 HTR2A HTR2A TNFSF11 TNFSF11 GAREM1 GAREM1 CCL24 CCL24 CCL26 CCL26 TNFRSF11A TNFRSF11A LOC103247784 LOC103247784 TGFB1 TGFB1 CXCL17 CXCL17 NECAB2 NECAB2 FBXW7 FBXW7 IGF1 IGF1 FGB FGB FGA FGA FGG FGG PDGFC PDGFC APOE APOE RAPGEF2 RAPGEF2 CD36 CD36 ABCA7 ABCA7 FGF1 FGF1 CALCR CALCR SCIMP SCIMP RIPK2 RIPK2 ALOX15 ALOX15 TLR4 TLR4 MAP2K1 MAP2K1 CRKL CRKL OPRM1 OPRM1 BMP2 BMP2 PTPRC PTPRC NPY5R NPY5R HAND2 HAND2 PRKD2 PRKD2 C5AR1 C5AR1 FGF21 FGF21 CCR7 CCR7 DDR2 DDR2 TRPV4 TRPV4 SLAMF1 SLAMF1 PTPN11 PTPN11 PHB PHB TIRAP TIRAP NTRK1 NTRK1 SHC1 SHC1 S100A7A S100A7A NOTCH2 NOTCH2 PTPN22 PTPN22
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDE8APhosphodiesterase. (829 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
ENSCSAP00000016690Prohibitin. (261 aa)
HCRTR1Hypocretin receptor 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
PLA2G5Phospholipase A(2). (138 aa)
PLA2G2APhospholipase A(2). (144 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
TPBGLTrophoblast glycoprotein like. (384 aa)
ENSCSAP00000017599annotation not available (271 aa)
ENSCSAP00000017683Prohibitin. (272 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (361 aa)
TPBGTrophoblast glycoprotein. (421 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
ENSCSAP00000018173Uncharacterized protein. (118 aa)
GPBAR1G protein-coupled bile acid receptor 1. (330 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
C5AR2Complement component 5a receptor 2. (337 aa)
ANGPT1Angiopoietin 1. (407 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CD74CD74 molecule. (294 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (260 aa)
TNFAIP8L3TNF alpha induced protein 8 like 3. (292 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
LOC103230639SCY domain-containing protein. (114 aa)
LOC103230637SCY domain-containing protein. (114 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
DDTLD-dopachrome tautomerase like. (131 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (294 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa)
CD4CD4 molecule. (560 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
CCL19C-C motif chemokine. (98 aa)
PHB2Prohibitin. (288 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ENSCSAP00000005731Protein kinase domain-containing protein. (479 aa)
ERBB4Protein kinase domain-containing protein. (622 aa)
HLA-DQB1Major histocompatibility complex, class II, DQ beta 1. (261 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
APPAmyloid beta precursor protein. (770 aa)
NELFENegative elongation factor complex member E. (380 aa)
FGFR4Fibroblast growth factor receptor. (806 aa)
GAREM2GRB2 associated regulator of MAPK1 subtype 2. (875 aa)
DNAJC27DnaJ heat shock protein family (Hsp40) member C27. (273 aa)
NODALNodal growth differentiation factor. (347 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (482 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (517 aa)
ENSCSAP00000004411SCY domain-containing protein. (142 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa)
IAPPIslet amyloid polypeptide. (89 aa)
GCNT2Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa)
CASRCalcium sensing receptor. (882 aa)
RASGRP1RAS guanyl releasing protein 1. (659 aa)
CCL20C-C motif chemokine. (96 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
ALKAL2ALK and LTK ligand 2. (154 aa)
PRXL2CPeroxiredoxin like 2C. (226 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CCL13C-C motif chemokine ligand 13; Belongs to the intercrine beta (chemokine CC) family. (98 aa)
CCL8C-C motif chemokine. (109 aa)
CCL1C-C motif chemokine. (107 aa)
ENSCSAP00000002584Prohibitin. (259 aa)
FFAR4Free fatty acid receptor 4. (361 aa)
CCL5C-C motif chemokine. (91 aa)
CCL16C-C motif chemokine. (112 aa)
CCL14C-C motif chemokine. (67 aa)
CCL15C-C motif chemokine. (109 aa)
CCL18C-C motif chemokine. (88 aa)
ENSCSAP00000002492C-C motif chemokine. (92 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ENSCSAP00000002431C-C motif chemokine. (92 aa)
PYCARDPYD and CARD domain containing. (195 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (857 aa)
CD44CD44 molecule (Indian blood group). (699 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1036 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
CCL22C-C motif chemokine ligand 22. (93 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
CCL17C-C motif chemokine. (91 aa)
NDRG4NDRG family member 4. (391 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
DENND2BSuppression of tumorigenicity 5. (1137 aa)
IL26Interleukin 26. (171 aa)
CAVIN3Caveolae associated protein 3. (263 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
SRCTyrosine-protein kinase. (633 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (669 aa)
NRXN1Neurexin 1. (831 aa)
THPOThrombopoietin. (353 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (495 aa)
GPNMBGlycoprotein nmb. (560 aa)
NPTNNeuroplastin. (398 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (501 aa)
AKAP12A-kinase anchoring protein 12. (1782 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (383 aa)
MTURNMaturin, neural progenitor differentiation regulator homolog. (131 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (931 aa)
ALKAL1ALK and LTK ligand 1. (129 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMPERBMP binding endothelial regulator. (685 aa)
FERMT2Fermitin family member 2. (507 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
GCGGlucagon. (180 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
RAMP3Receptor activity modifying protein 3. (201 aa)
SLC30A10Solute carrier family 30 member 10. (485 aa)
CARD9Caspase recruitment domain family member 9. (499 aa)
NRG1Neuregulin 1. (467 aa)
NOTCH1Notch receptor 1. (2555 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ADRA1AAdrenoceptor alpha 1A. (425 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CCN2Cellular communication network factor 2. (349 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1052 aa)
GATA4GATA binding protein 4. (442 aa)
CIB1Calcium and integrin binding 1. (191 aa)
GAS6Growth arrest specific 6. (542 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
ENSCSAP00000013641GLUCAGON domain-containing protein. (322 aa)
S100A7L2S100 calcium binding protein A7 like 2. (107 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
GAREM1GRB2 associated regulator of MAPK1 subtype 1. (876 aa)
CCL24C-C motif chemokine ligand 24. (119 aa)
CCL26C-C motif chemokine. (94 aa)
TNFRSF11ATNF receptor superfamily member 11a. (561 aa)
LOC103247784C-C motif chemokine. (93 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
NECAB2N-terminal EF-hand calcium binding protein 2. (303 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
IGF1Insulin like growth factor 1. (159 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (875 aa)
FGGFibrinogen gamma chain. (437 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1685 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
ABCA7ATP binding cassette subfamily A member 7. (2149 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
SCIMPSLP adaptor and CSK interacting membrane protein. (145 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
ALOX15Arachidonate 15-lipoxygenase. (610 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1309 aa)
NPY5RNeuropeptide Y receptor Y5. (287 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (406 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (824 aa)
SLAMF1Signaling lymphocytic activation molecule family member 1. (335 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
PHBProhibitin. (272 aa)
TIRAPTIR domain containing adaptor protein. (220 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SHC1SHC adaptor protein 1. (474 aa)
S100A7AProtein S100; Belongs to the S-100 family. (119 aa)
NOTCH2Notch receptor 2. (2471 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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