STRINGSTRING
CTNNB1 CTNNB1 AHI1 AHI1 TCF21 TCF21 NOTCH1 NOTCH1 LAMA5 LAMA5 GLI3 GLI3 BMP4 BMP4 AQP1 AQP1 MEF2C MEF2C HOXD11 HOXD11 HOXA11 HOXA11 SIX1 SIX1 CALB1 CALB1 EYA1 EYA1 JAG1 JAG1 BMP2 BMP2 GATA3 GATA3 KLHL3 KLHL3 TFAP2B TFAP2B NOTCH2 NOTCH2 WNK4 WNK4 COMMD5 COMMD5 POU3F3 POU3F3 GREM1 GREM1 LZTS2 LZTS2 FGF8 FGF8 WNT7B WNT7B SALL1 SALL1 TMEM59L TMEM59L IRX3 IRX3 WT1 WT1 LGR4 LGR4 SOX9 SOX9 DCHS1 DCHS1 PKD2 PKD2 WNT11 WNT11 AQP11 AQP11 WNT9B WNT9B FGF2 FGF2 PAX2 PAX2 HNF1B HNF1B WNT1 WNT1 PTCH1 PTCH1 SHH SHH FMN1 FMN1 ENSCSAP00000003756 ENSCSAP00000003756 GREB1 GREB1 GPC3 GPC3 OSR1 OSR1 WNT6 WNT6 DLG1 DLG1 HS3ST3B1 HS3ST3B1 HS3ST3A1 HS3ST3A1 KIF26B KIF26B MTSS1 MTSS1 PBX1 PBX1 PKD1 PKD1 GZF1 GZF1 CITED1 CITED1 DLL1 DLL1 SOX8 SOX8 PGF PGF FGF1 FGF1 BCL2 BCL2 NOG NOG HES5 HES5 CTNNBIP1 CTNNBIP1 WNT4 WNT4 HEYL HEYL TACSTD2 TACSTD2 HS2ST1 HS2ST1 SMAD4 SMAD4 GREB1L GREB1L IRX2 IRX2 IRX1 IRX1 ADAMTS16 ADAMTS16 GDNF GDNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNB1Catenin beta 1. (781 aa)
AHI1Abelson helper integration site 1. (1202 aa)
TCF21Transcription factor 21. (179 aa)
NOTCH1Notch receptor 1. (2555 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
GLI3GLI family zinc finger 3. (1459 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
HOXD11Homeobox D11. (338 aa)
HOXA11Homeobox A11. (310 aa)
SIX1SIX homeobox 1. (284 aa)
CALB1Calbindin 1. (261 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (586 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
GATA3GATA binding protein 3. (443 aa)
KLHL3Kelch like family member 3. (587 aa)
TFAP2BTranscription factor AP-2 beta. (471 aa)
NOTCH2Notch receptor 2. (2471 aa)
WNK4Protein kinase domain-containing protein. (483 aa)
COMMD5COMM domain containing 5. (224 aa)
POU3F3POU domain protein. (452 aa)
GREM1Gremlin. (184 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
SALL1Spalt like transcription factor 1. (1321 aa)
TMEM59LTransmembrane protein 59 like. (343 aa)
IRX3Iroquois homeobox 3. (416 aa)
WT1WT1 transcription factor. (320 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (951 aa)
SOX9SRY-box transcription factor 9. (509 aa)
DCHS1Dachsous cadherin-related 1. (3296 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (859 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (271 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
PAX2Paired box 2. (261 aa)
HNF1BHNF1 homeobox B. (557 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PTCH1Patched 1. (1452 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
FMN1Formin 1. (1291 aa)
ENSCSAP00000003756Uncharacterized protein. (400 aa)
GREB1Uncharacterized protein. (1418 aa)
GPC3Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (452 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DLG1Uncharacterized protein; Belongs to the MAGUK family. (800 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (390 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (406 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1660 aa)
MTSS1MTSS I-BAR domain containing 1. (690 aa)
PBX1PBX homeobox 1. (301 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (3853 aa)
GZF1GDNF inducible zinc finger protein 1. (712 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
SOX8SRY-box transcription factor 8. (446 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
TACSTD2Tumor associated calcium signal transducer 2. (339 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1. (298 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1873 aa)
IRX2Iroquois homeobox 2. (378 aa)
IRX1Iroquois homeobox 1. (418 aa)
ADAMTS16ADAM metallopeptidase with thrombospondin type 1 motif 16. (889 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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