STRINGSTRING
CACNA1D CACNA1D KCNA5 KCNA5 KCNE4 KCNE4 KCNE1 KCNE1 KCNE2 KCNE2 KCNE5 KCNE5 KCNJ2 KCNJ2 KCNE3 KCNE3 KCNJ5 KCNJ5 SCN2B SCN2B SCN4B SCN4B NUP155 NUP155 GJA1 GJA1 KCNJ3 KCNJ3 SCN1A SCN1A KCNN2 KCNN2 SCN5A SCN5A CACNB2 CACNB2 SNTA1 SNTA1 CACNA2D1 CACNA2D1 CACNA1C CACNA1C CAV3 CAV3 RYR2 RYR2 ANK2 ANK2 SCN1B SCN1B CACNA1G CACNA1G KCNH2 KCNH2 PKP2 PKP2 KCNJ8 KCNJ8 KCNQ1 KCNQ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
KCNE1Uncharacterized protein. (146 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
NUP155Nucleoporin 155. (1080 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
SCN1ASodium voltage-gated channel alpha subunit 1. (1359 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (846 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1881 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
SNTA1Syntrophin alpha 1. (505 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
RYR2Ryanodine receptor 2. (4906 aa)
ANK2Ankyrin 2. (4035 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2186 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1160 aa)
PKP2Plakophilin 2. (837 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (518 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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