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| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (413 aa) |
| | ZNF423 | Zinc finger protein 423. (1284 aa) |
| | FBXL15 | F-box and leucine rich repeat protein 15. (300 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (179 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | EP300 | E1A binding protein p300. (2416 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | GIPC1 | GIPC PDZ domain containing family member 1. (333 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa) |
| | DAND5 | DAN domain BMP antagonist family member 5. (189 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (266 aa) |
| | ADAM17 | ADAM metallopeptidase domain 17. (824 aa) |
| | ASPN | Asporin. (374 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (444 aa) |
| | THBS1 | Thrombospondin 1. (1170 aa) |
| | UBE2D1 | Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | MEN1 | Menin 1. (610 aa) |
| | BMP6 | Bone morphogenetic protein 6. (433 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | PBLD | Phenazine biosynthesis like protein domain containing. (288 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa) |
| | TET1 | Tet methylcytosine dioxygenase 1. (2132 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | KIAA0319 | KIAA0319. (912 aa) |
| | FAM89B | Family with sequence similarity 89 member B. (189 aa) |
| | IGSF1 | Immunoglobulin superfamily member 1. (1304 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (300 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | ENSCSAP00000004237 | Uncharacterized protein. (1238 aa) |
| | GDF7 | Growth differentiation factor 7. (447 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (314 aa) |
| | BRMS1 | BRMS1 transcriptional repressor and anoikis regulator. (246 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | STRAP | Serine/threonine kinase receptor associated protein. (350 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | FLCN | Folliculin. (579 aa) |
| | DMRT1 | Doublesex and mab-3 related transcription factor 1. (278 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (732 aa) |
| | CHRDL1 | Chordin like 1. (458 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | ZC3H3 | Zinc finger CCCH-type containing 3. (964 aa) |
| | MYOCD | Myocardin. (986 aa) |
| | CER1 | Cerberus 1, DAN family BMP antagonist. (267 aa) |
| | VWC2L | Von Willebrand factor C domain containing 2 like. (174 aa) |
| | EMILIN1 | Elastin microfibril interfacer 1. (860 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (329 aa) |
| | CTDSPL2 | CTD small phosphatase like 2. (466 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | CREBBP | CREB binding protein. (2417 aa) |
| | LEMD2 | LEM domain containing 2. (509 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (137 aa) |
| | GDF3 | Growth differentiation factor 3. (364 aa) |
| | SCUBE3 | Signal peptide, CUB domain and EGF like domain containing 3. (993 aa) |
| | XBP1 | X-box binding protein 1. (261 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa) |
| | ARID4B | AT-rich interaction domain 4B. (1314 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | LRG1 | Leucine rich alpha-2-glycoprotein 1. (347 aa) |
| | FBN1 | Fibrillin 1. (2666 aa) |
| | ZBTB7A | Zinc finger and BTB domain containing 7A. (584 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | SAP30L | SAP30 like. (184 aa) |
| | CCN3 | Cellular communication network factor 3. (357 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | GIPC3 | GIPC PDZ domain containing family member 3. (312 aa) |
| | OGT | O-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | LTBP1 | Latent transforming growth factor beta binding protein 1. (1724 aa) |
| | ZEB1 | Zinc finger E-box binding homeobox 1. (1124 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | SNW1 | SNW domain containing 1. (536 aa) |
| | ENSCSAP00000008056 | Uncharacterized protein. (534 aa) |
| | CRIM1 | Cysteine rich transmembrane BMP regulator 1. (1036 aa) |
| | DACT2 | Dishevelled binding antagonist of beta catenin 2. (643 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | RNF111 | Ring finger protein 111. (985 aa) |
| | VEPH1 | Ventricular zone expressed PH domain containing 1. (833 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | KIAA1324L | KIAA1324 like. (915 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (724 aa) |
| | GDF6 | Growth differentiation factor 6. (455 aa) |
| | RBPMS2 | RNA binding protein, mRNA processing factor 2. (217 aa) |
| | WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | BMP15 | Bone morphogenetic protein 15. (393 aa) |
| | FSTL3 | Follistatin like 3. (263 aa) |
| | IL17RD | Interleukin 17 receptor D. (595 aa) |
| | CILP | Cartilage intermediate layer protein. (1184 aa) |
| | AXIN1 | Axin 1. (867 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | TFAP2B | Transcription factor AP-2 beta. (471 aa) |
| | C20orf27 | Chromosome 20 open reading frame 27. (174 aa) |
| | IL17F | Interleukin 17F. (163 aa) |
| | UCMA | Upper zone of growth plate and cartilage matrix associated. (140 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | MPP5 | Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa) |
| | SKOR1 | SKI family transcriptional corepressor 1. (964 aa) |
| | ZNF451 | Zinc finger protein 451. (1061 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (206 aa) |
| | CRB2 | Crumbs cell polarity complex component 2. (1287 aa) |
| | FERMT1 | Fermitin family member 1. (677 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | HSPA5 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa) |
| | GREM1 | Gremlin. (184 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (956 aa) |
| | ENG | Endoglin. (658 aa) |
| | SULF1 | Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa) |
| | NEO1 | Neogenin 1. (1465 aa) |
| | CD109 | CD109 molecule. (1201 aa) |
| | FBN2 | Fibrillin 2. (2916 aa) |
| | PPM1A | Protein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa) |
| | HOXA13 | Homeobox A13. (391 aa) |
| | SPINT3 | Serine peptidase inhibitor, Kunitz type 3. (89 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1273 aa) |
| | ENSCSAP00000010642 | Uncharacterized protein. (241 aa) |
| | LOX | Lysyl oxidase. (417 aa) |
| | ABL1 | Tyrosine-protein kinase. (1130 aa) |
| | DLX1 | Distal-less homeobox 1. (255 aa) |
| | SPRED2 | Sprouty related EVH1 domain containing 2. (415 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | SLC2A10 | Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | TBX20 | T-box transcription factor 20. (447 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | NREP | Neuronal regeneration related protein. (68 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | LRP2 | LDL receptor related protein 2. (3861 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | HTRA4 | HtrA serine peptidase 4. (478 aa) |
| | ADAMTSL2 | ADAMTS like 2. (958 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | NKX2-1 | NK2 homeobox 1. (371 aa) |
| | BRMS1L | BRMS1 like transcriptional repressor. (323 aa) |
| | PMEPA1 | Prostate transmembrane protein, androgen induced 1. (287 aa) |
| | ZNF703 | Zinc finger protein 703. (590 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | RBPMS | RNA binding protein, mRNA processing factor. (219 aa) |
| | NOTCH1 | Notch receptor 1. (2555 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | HTRA3 | HtrA serine peptidase 3. (470 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | TNFAIP6 | TNF alpha induced protein 6. (277 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | ZEB2 | Zinc finger E-box binding homeobox 2. (1217 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | LEFTY1 | Left-right determination factor. (366 aa) |
| | LEFTY2 | Left-right determination factor. (366 aa) |
| | PARP1 | Poly(ADP-ribose) polymerase 1. (709 aa) |
| | FST | Follistatin. (344 aa) |
| | INHBB | Inhibin subunit beta B. (320 aa) |
| | PELO | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (839 aa) |
| | SAP130 | Sin3A associated protein 130. (1056 aa) |
| | GATA4 | GATA binding protein 4. (442 aa) |
| | DAB2 | DAB adaptor protein 2. (770 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (450 aa) |
| | LATS1 | Large tumor suppressor kinase 1. (1130 aa) |
| | ING1 | Inhibitor of growth protein. (279 aa) |
| | LDLRAD4 | Low density lipoprotein receptor class A domain containing 4. (269 aa) |
| | CIDEA | Cell death inducing DFFA like effector a. (120 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | GATA6 | GATA binding protein 6. (595 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (728 aa) |
| | SPART | Spartin. (666 aa) |
| | UBL3 | Ubiquitin-like protein. (117 aa) |
| | SKOR2 | SKI family transcriptional corepressor 2. (1001 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa) |
| | ONECUT2 | One cut domain family member. (504 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1. (580 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | SOST | Sclerostin. (213 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | SAP30 | Sin3A associated protein 30. (220 aa) |
| | ING2 | Inhibitor of growth protein. (280 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | SNX25 | Sorting nexin 25. (859 aa) |
| | BCL9L | BCL9 like. (1500 aa) |
| | SORL1 | Sortilin related receptor 1. (2214 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (425 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | TRIM33 | Tripartite motif containing 33. (1127 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (860 aa) |
| | CCN1 | Cellular communication network factor 1. (381 aa) |
| | GIPC2 | GIPC PDZ domain containing family member 2. (315 aa) |
| | ENSCSAP00000016646 | Peptidyl-prolyl cis-trans isomerase. (157 aa) |
| | ENSCSAP00000016878 | TGF_BETA_2 domain-containing protein. (354 aa) |
| | ENSCSAP00000016884 | TGF_BETA_2 domain-containing protein. (292 aa) |
| | ENSCSAP00000016885 | TGFb_propeptide domain-containing protein. (144 aa) |
| | NBL1 | Neuroblastoma suppressor of tumorigenicity 1. (181 aa) |
| | PRDM16 | PR/SET domain 16. (839 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (166 aa) |
| | SKI | SKI proto-oncogene. (728 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | SPRY1 | Sprouty RTK signaling antagonist 1. (319 aa) |
| | SOX11 | Transcription factor SOX. (441 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) |
| | LINGO3 | Leucine rich repeat and Ig domain containing 3. (592 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (236 aa) |
| | SPRY2 | Sprouty RTK signaling antagonist 2. (315 aa) |
| | SDCBP | Uncharacterized protein. (293 aa) |
| | GREM2 | Gremlin. (168 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (649 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1557 aa) |
| | CHRDL2 | Chordin like 2. (429 aa) |
| | SMURF2 | SMAD specific E3 ubiquitin protein ligase 2. (474 aa) |
| | SPRED3 | Sprouty related EVH1 domain containing 3. (423 aa) |
| | NUMA1 | Nuclear mitotic apparatus protein 1. (2118 aa) |
| | LEMD3 | LEM domain containing 3. (911 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa) |
| | GLG1 | Golgi glycoprotein 1. (1051 aa) |
| | HTRA1 | HtrA serine peptidase 1. (524 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (350 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | LRP1 | LDL receptor related protein 1. (4544 aa) |
| | RASL11B | RAS like family 11 member B. (248 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa) |
| | UBE2O | Ubiquitin conjugating enzyme E2 O. (1293 aa) |
| | CILP2 | Cartilage intermediate layer protein 2. (1156 aa) |
| | ITGA3 | Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1049 aa) |
| | GDF11 | Growth differentiation factor 11. (406 aa) |
