STRINGSTRING
FGFR1 FGFR1 LEMD3 LEMD3 NUMA1 NUMA1 CRB2 CRB2 SOSTDC1 SOSTDC1 GATA3 GATA3 ZNF451 ZNF451 SKOR1 SKOR1 MPP5 MPP5 DAB2IP DAB2IP SMAD3 SMAD3 SMAD6 SMAD6 IL17F IL17F C20orf27 C20orf27 TFAP2B TFAP2B WNT5A WNT5A ITGA8 ITGA8 AXIN1 AXIN1 IL17RD IL17RD FSTL3 FSTL3 SKIL SKIL WFIKKN1 WFIKKN1 RBPMS2 RBPMS2 RUNX2 RUNX2 HSP90AB1 HSP90AB1 SPRY4 SPRY4 FGF1 FGF1 KIAA1324L KIAA1324L STUB1 STUB1 STK11 STK11 IL12A IL12A VEPH1 VEPH1 RNF111 RNF111 TGFB3 TGFB3 SMOC2 SMOC2 CRIM1 CRIM1 DLL1 DLL1 NEDD4 NEDD4 SNW1 SNW1 BAMBI BAMBI JCAD JCAD ZEB1 ZEB1 LTBP1 LTBP1 TMEM204 TMEM204 NRP1 NRP1 TP53 TP53 XDH XDH OGT OGT GIPC3 GIPC3 PIK3CB PIK3CB CITED1 CITED1 CAV1 CAV1 SAP30L SAP30L CAV3 CAV3 ZBTB7A ZBTB7A TMEM108 TMEM108 AGT AGT FBN1 FBN1 LRG1 LRG1 BMPR2 BMPR2 GDF5 GDF5 ARID4B ARID4B GDF2 GDF2 XBP1 XBP1 SCUBE3 SCUBE3 GDF3 GDF3 CDKN2B CDKN2B MMRN2 MMRN2 LEMD2 LEMD2 FGF18 FGF18 CREBBP CREBBP CTDSPL2 CTDSPL2 CDKN1C CDKN1C EMILIN1 EMILIN1 PTP4A3 PTP4A3 VWC2L VWC2L FGF4 FGF4 CER1 CER1 MYOCD MYOCD CHRDL1 CHRDL1 NRROS NRROS FLCN FLCN APLN APLN HIPK2 HIPK2 STRAP STRAP BRMS1 BRMS1 TGFBR3L TGFBR3L EPN2 EPN2 FAM89B FAM89B PIN1 PIN1 TET1 TET1 TMPRSS6 TMPRSS6 SLC9A6 SLC9A6 PBLD PBLD PPP2R5B PPP2R5B SIRT1 SIRT1 MEN1 MEN1 UBE2D1 UBE2D1 THBS1 THBS1 SPRED1 SPRED1 ASPN ASPN ADAM17 ADAM17 DKK1 DKK1 VEGFB VEGFB DNM2 DNM2 NF1 NF1 PRKCB PRKCB CYFIP1 CYFIP1 HHEX HHEX DAND5 DAND5 GIPC1 GIPC1 WNT1 WNT1 BMP2 BMP2 HSPA5 HSPA5 NRXN1 NRXN1 CHRD CHRD NIBAN2 NIBAN2 IL4 IL4 ENG ENG PRDM14 PRDM14 SULF1 SULF1 NEO1 NEO1 NPTN NPTN MYO1C MYO1C CD109 CD109 HIF1A HIF1A DMD DMD FBN2 FBN2 HRG HRG ENSCSAP00000010271 ENSCSAP00000010271 PPM1A PPM1A HOXA13 HOXA13 ATP2B4 ATP2B4 SPINT3 SPINT3 SIN3A SIN3A ENSCSAP00000010642 ENSCSAP00000010642 OTX2 OTX2 DSTYK DSTYK LOX LOX SEMA6A SEMA6A ABL1 ABL1 DLX1 DLX1 SPRED2 SPRED2 BMP4 BMP4 SLC2A10 SLC2A10 BMPER BMPER SULF2 SULF2 TBX20 TBX20 NREP NREP SFRP4 SFRP4 SFRP1 SFRP1 PTPN1 PTPN1 LRP2 LRP2 DOK5 DOK5 HTRA4 HTRA4 ADAMTSL2 ADAMTSL2 WASF1 WASF1 NKX2-1 NKX2-1 BRMS1L BRMS1L PMEPA1 PMEPA1 ADGRA2 ADGRA2 ZNF703 ZNF703 HDAC2 HDAC2 NOTCH1 NOTCH1 HTRA3 HTRA3 VWC2 VWC2 GRB10 GRB10 TNFAIP6 TNFAIP6 ZEB2 ZEB2 MSX1 MSX1 ENSCSAP00000012589 ENSCSAP00000012589 SLIT2 SLIT2 FST FST PELO PELO FGF10 FGF10 PCSK6 PCSK6 SAP130 SAP130 CTNNB1 CTNNB1 GATA4 GATA4 DAB2 DAB2 RGMA RGMA ADAMTS12 ADAMTS12 LATS1 LATS1 ING1 ING1 LDLRAD4 LDLRAD4 CIDEA CIDEA FAM20C FAM20C TWSG1 TWSG1 GATA6 GATA6 SMURF1 SMURF1 SPART SPART UBL3 UBL3 SHISA2 SHISA2 SKOR2 SKOR2 SMAD2 SMAD2 SMAD7 SMAD7 ARNT ARNT FGF9 FGF9 SMAD4 SMAD4 LATS2 LATS2 ONECUT2 ONECUT2 CCBE1 CCBE1 PDPK1 PDPK1 FZD4 FZD4 TGFB1 TGFB1 SOST SOST HHIP HHIP SFRP2 SFRP2 SAP30 SAP30 VEGFC VEGFC PRKD2 PRKD2 ING2 ING2 CHST11 CHST11 SNX25 SNX25 BCL9L BCL9L NGFR NGFR FERMT1 FERMT1 SORL1 SORL1 FUZ FUZ HGS HGS HJV HJV NOTCH2 NOTCH2 TRIM33 TRIM33 TGFBR3 TGFBR3 CCN1 CCN1 GIPC2 GIPC2 ENSCSAP00000016646 ENSCSAP00000016646 WNT4 WNT4 NBL1 NBL1 PRDM16 PRDM16 HES5 HES5 SKI SKI NOG NOG SPRY3 SPRY3 SPRY1 SPRY1 SOX11 SOX11 CITED2 CITED2 FGFBP3 FGFBP3 LINGO3 LINGO3 EID2 EID2 SPRY2 SPRY2 SDCBP SDCBP FZD1 FZD1 GREM2 GREM2 AGTR2 AGTR2 FGFBP1 FGFBP1 GREM1 GREM1 GPC1 GPC1 ROBO1 ROBO1 EP300 EP300 ACVRL1 ACVRL1 SFRP5 SFRP5 MTMR4 MTMR4 CREB3L1 CREB3L1 WFIKKN2 WFIKKN2 FBXL15 FBXL15 ZNF423 ZNF423 ITGA5 ITGA5 FKBP8 FKBP8 CD63 CD63 PPARA PPARA ITGA3 ITGA3 MT3 MT3 UBE2O UBE2O KDR KDR RASL11B RASL11B ADAMTS3 ADAMTS3 CDH5 CDH5 DKK3 DKK3 HTRA1 HTRA1 CXCL13 CXCL13 GLG1 GLG1 LTBP4 LTBP4 DCN DCN ITGB3 ITGB3 LRIT3 LRIT3 CHRDL2 CHRDL2 ZDHHC17 ZDHHC17 SMURF2 SMURF2 SPRED3 SPRED3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FGFR1Fibroblast growth factor receptor. (830 aa)
LEMD3LEM domain containing 3. (911 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2118 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
GATA3GATA binding protein 3. (443 aa)
ZNF451Zinc finger protein 451. (1061 aa)
SKOR1SKI family transcriptional corepressor 1. (964 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
DAB2IPDAB2 interacting protein. (1036 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
IL17FInterleukin 17F. (163 aa)
C20orf27Chromosome 20 open reading frame 27. (174 aa)
TFAP2BTranscription factor AP-2 beta. (471 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
AXIN1Axin 1. (867 aa)
IL17RDInterleukin 17 receptor D. (595 aa)
FSTL3Follistatin like 3. (263 aa)
SKILSKI like proto-oncogene. (684 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
RBPMS2RNA binding protein, mRNA processing factor 2. (217 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (450 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
SPRY4Sprouty RTK signaling antagonist 4. (322 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
KIAA1324LKIAA1324 like. (915 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
VEPH1Ventricular zone expressed PH domain containing 1. (833 aa)
RNF111Ring finger protein 111. (985 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
SMOC2SPARC related modular calcium binding 2. (446 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1036 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
SNW1SNW domain containing 1. (536 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
JCADJunctional cadherin 5 associated. (1357 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1124 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1724 aa)
TMEM204Transmembrane protein 204. (226 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
XDHXanthine dehydrogenase. (1339 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
GIPC3GIPC PDZ domain containing family member 3. (312 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
CITED1Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
SAP30LSAP30 like. (184 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
TMEM108Transmembrane protein 108. (575 aa)
AGTAngiotensinogen; Belongs to the serpin family. (485 aa)
FBN1Fibrillin 1. (2666 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
GDF5Growth differentiation factor 5. (499 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
GDF2Growth differentiation factor 2. (429 aa)
XBP1X-box binding protein 1. (261 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
GDF3Growth differentiation factor 3. (364 aa)
CDKN2BCyclin dependent kinase inhibitor 2B. (137 aa)
MMRN2Multimerin 2. (951 aa)
LEMD2LEM domain containing 2. (509 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CREBBPCREB binding protein. (2417 aa)
CTDSPL2CTD small phosphatase like 2. (466 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (329 aa)
EMILIN1Elastin microfibril interfacer 1. (860 aa)
PTP4A3Protein tyrosine phosphatase 4A3. (173 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (174 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
MYOCDMyocardin. (986 aa)
CHRDL1Chordin like 1. (458 aa)
NRROSNegative regulator of reactive oxygen species. (732 aa)
FLCNFolliculin. (579 aa)
APLNApelin. (77 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
STRAPSerine/threonine kinase receptor associated protein. (350 aa)
BRMS1BRMS1 transcriptional repressor and anoikis regulator. (246 aa)
TGFBR3LTransforming growth factor beta receptor 3 like. (314 aa)
EPN2Epsin 2. (584 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
TET1Tet methylcytosine dioxygenase 1. (2132 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa)
SLC9A6Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (702 aa)
PBLDPhenazine biosynthesis like protein domain containing. (288 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
SIRT1Sirtuin 1. (743 aa)
MEN1Menin 1. (610 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
THBS1Thrombospondin 1. (1170 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
ASPNAsporin. (374 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (188 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
NF1Neurofibromin 1. (2849 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
HHEXHematopoietically expressed homeobox. (268 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
NRXN1Neurexin 1. (831 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (956 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
ENGEndoglin. (658 aa)
PRDM14PR/SET domain 14. (571 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
NEO1Neogenin 1. (1465 aa)
NPTNNeuroplastin. (398 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1011 aa)
CD109CD109 molecule. (1201 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
DMDUncharacterized protein. (774 aa)
FBN2Fibrillin 2. (2916 aa)
HRGHistidine rich glycoprotein. (521 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
HOXA13Homeobox A13. (391 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1170 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
ENSCSAP00000010642Uncharacterized protein. (241 aa)
OTX2Orthodenticle homeobox 2. (223 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (931 aa)
LOXLysyl oxidase. (417 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1043 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
DLX1Distal-less homeobox 1. (255 aa)
SPRED2Sprouty related EVH1 domain containing 2. (415 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SLC2A10Solute carrier family 2 member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)
BMPERBMP binding endothelial regulator. (685 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (950 aa)
TBX20T-box transcription factor 20. (447 aa)
NREPNeuronal regeneration related protein. (68 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
LRP2LDL receptor related protein 2. (3861 aa)
DOK5Docking protein 5. (306 aa)
HTRA4HtrA serine peptidase 4. (478 aa)
ADAMTSL2ADAMTS like 2. (958 aa)
WASF1WASP family member 1. (559 aa)
NKX2-1NK2 homeobox 1. (371 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
PMEPA1Prostate transmembrane protein, androgen induced 1. (287 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1338 aa)
ZNF703Zinc finger protein 703. (590 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
NOTCH1Notch receptor 1. (2555 aa)
HTRA3HtrA serine peptidase 3. (470 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
GRB10Growth factor receptor bound protein 10. (593 aa)
TNFAIP6TNF alpha induced protein 6. (277 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1217 aa)
MSX1Msh homeobox 1. (303 aa)
ENSCSAP00000012589LRRNT domain-containing protein. (132 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
FSTFollistatin. (344 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (839 aa)
SAP130Sin3A associated protein 130. (1056 aa)
CTNNB1Catenin beta 1. (781 aa)
GATA4GATA binding protein 4. (442 aa)
DAB2DAB adaptor protein 2. (770 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (450 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1598 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
ING1Inhibitor of growth protein. (279 aa)
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (269 aa)
CIDEACell death inducing DFFA like effector a. (120 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (584 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
GATA6GATA binding protein 6. (595 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
SPARTSpartin. (666 aa)
UBL3Ubiquitin-like protein. (117 aa)
SHISA2Shisa family member 2. (295 aa)
SKOR2SKI family transcriptional corepressor 2. (1001 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
LATS2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
ONECUT2One cut domain family member. (504 aa)
CCBE1Collagen and calcium binding EGF domains 1. (336 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SOSTSclerostin. (213 aa)
HHIPHedgehog interacting protein. (682 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SAP30Sin3A associated protein 30. (220 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
ING2Inhibitor of growth protein. (280 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
SNX25Sorting nexin 25. (859 aa)
BCL9LBCL9 like. (1500 aa)
NGFRNerve growth factor receptor. (427 aa)
FERMT1Fermitin family member 1. (677 aa)
SORL1Sortilin related receptor 1. (2214 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
HJVHemojuvelin BMP co-receptor. (425 aa)
NOTCH2Notch receptor 2. (2471 aa)
TRIM33Tripartite motif containing 33. (1127 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
CCN1Cellular communication network factor 1. (381 aa)
GIPC2GIPC PDZ domain containing family member 2. (315 aa)
ENSCSAP00000016646Peptidyl-prolyl cis-trans isomerase. (157 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (181 aa)
PRDM16PR/SET domain 16. (839 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
SKISKI proto-oncogene. (728 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
SOX11Transcription factor SOX. (441 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
FGFBP3Fibroblast growth factor binding protein 3. (260 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (592 aa)
EID2EP300 interacting inhibitor of differentiation 2. (236 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
SDCBPUncharacterized protein. (293 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (649 aa)
GREM2Gremlin. (168 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
GREM1Gremlin. (184 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
ROBO1Uncharacterized protein. (1466 aa)
EP300E1A binding protein p300. (2416 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SFRP5Secreted frizzled related protein 5. (179 aa)
MTMR4Myotubularin related protein 4. (1195 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
ZNF423Zinc finger protein 423. (1284 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
CD63Tetraspanin. (238 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1049 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
RASL11BRAS like family 11 member B. (248 aa)
ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3. (1035 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
HTRA1HtrA serine peptidase 1. (524 aa)
CXCL13C-X-C motif chemokine. (109 aa)
GLG1Golgi glycoprotein 1. (1051 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1557 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (678 aa)
CHRDL2Chordin like 2. (429 aa)
ZDHHC17Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (632 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (474 aa)
SPRED3Sprouty related EVH1 domain containing 3. (423 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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