STRINGSTRING
PROX1 PROX1 ASPM ASPM DLL1 DLL1 PRRX1 PRRX1 MMP24 MMP24 JAG1 JAG1 FANCD2 FANCD2 FANCC FANCC REST REST HES5 HES5 IGF2BP1 IGF2BP1 SRRT SRRT FOXO1 FOXO1 CDH2 CDH2 SS18 SS18 MCPH1 MCPH1 PCM1 PCM1 HOOK3 HOOK3 NOTCH1 NOTCH1 FUT10 FUT10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PROX1Prospero homeobox 1. (737 aa)
ASPMAbnormal spindle microtubule assembly. (2794 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
PRRX1Paired related homeobox 1. (217 aa)
MMP24Matrix metallopeptidase 24. (573 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
FANCD2Uncharacterized protein. (1458 aa)
FANCCFanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (559 aa)
RESTRE1 silencing transcription factor. (1096 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
SRRTSerrate, RNA effector molecule. (876 aa)
FOXO1Forkhead box O1. (655 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
SS18SS18 subunit of BAF chromatin remodeling complex. (418 aa)
MCPH1Microcephalin 1. (842 aa)
PCM1Pericentriolar material 1. (2073 aa)
HOOK3Hook microtubule tethering protein 3. (698 aa)
NOTCH1Notch receptor 1. (2555 aa)
FUT10Alpha-(1,3)-fucosyltransferase; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. (479 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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