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GRM5 GRM5 PPP3CA PPP3CA CACNG4 CACNG4 CDH11 CDH11 INA INA GRASP GRASP P2RX3 P2RX3 CTNND1 CTNND1 STX3 STX3 GIPC1 GIPC1 GSG1L GSG1L CACNG3 CACNG3 CDK5 CDK5 TUBB2A TUBB2A DTNBP1 DTNBP1 LRRC4C LRRC4C CHRM1 CHRM1 LRRC4 LRRC4 ADRB1 ADRB1 DVL1 DVL1 PRKCZ PRKCZ NTNG1 NTNG1 SHANK1 SHANK1 BAIAP2 BAIAP2 FBXL20 FBXL20 CADM1 CADM1 EPHA4 EPHA4 CACNG2 CACNG2 GABBR1 GABBR1 APBA1 APBA1 ADORA2B ADORA2B DGKI DGKI PTPRD PTPRD WNT7A WNT7A SYN2 SYN2 PTPRS PTPRS GHRL GHRL ADCY8 ADCY8 ITPR1 ITPR1 LRFN2 LRFN2 PFN2 PFN2 TNR TNR ENSCSAP00000008408 ENSCSAP00000008408 IQSEC2 IQSEC2 GHSR GHSR SYP SYP LRRTM2 LRRTM2 PTPRA PTPRA DGKB DGKB SYN1 SYN1 NRXN1 NRXN1 NPTN NPTN ABR ABR BCR BCR MPP6 MPP6 AKAP12 AKAP12 PPP3R1 PPP3R1 NTNG2 NTNG2 BSN BSN PLAT PLAT FYN FYN ADCY1 ADCY1 NEFL NEFL CTNNB1 CTNNB1 ENSCSAP00000013169 ENSCSAP00000013169 GRM1 GRM1 EFNB2 EFNB2 ENSCSAP00000013783 ENSCSAP00000013783 DCC DCC MPP2 MPP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRM5Glutamate metabotropic receptor 5. (729 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CDH11Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
INAInternexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family. (499 aa)
GRASPGeneral receptor for phosphoinositides 1 associated scaffold protein. (395 aa)
P2RX3Purinergic receptor P2X 3. (298 aa)
CTNND1Catenin delta 1. (962 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (289 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
GSG1LGSG1 like. (330 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
LRRC4Leucine rich repeat containing 4. (653 aa)
ADRB1Adrenoceptor beta 1. (482 aa)
DVL1Dishevelled segment polarity protein 1. (574 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
NTNG1Netrin G1. (457 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2173 aa)
BAIAP2BAI1 associated protein 2. (595 aa)
FBXL20F-box and leucine rich repeat protein 20. (436 aa)
CADM1Cell adhesion molecule 1. (323 aa)
EPHA4EPH receptor A4. (986 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (837 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (331 aa)
DGKIDiacylglycerol kinase. (809 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1916 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
SYN2Synapsin II. (483 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1941 aa)
GHRLGhrelin and obestatin prepropeptide. (141 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (808 aa)
PFN2Profilin; Belongs to the profilin family. (392 aa)
TNRTenascin R. (1034 aa)
ENSCSAP00000008408Rho-GAP domain-containing protein. (271 aa)
IQSEC2IQ motif and Sec7 domain 2. (1208 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SYPSynaptophysin. (313 aa)
LRRTM2Leucine rich repeat transmembrane neuronal 2. (516 aa)
PTPRAProtein tyrosine phosphatase receptor type A. (881 aa)
DGKBDiacylglycerol kinase. (706 aa)
SYN1Synapsin I. (683 aa)
NRXN1Neurexin 1. (831 aa)
NPTNNeuroplastin. (398 aa)
ABRABR activator of RhoGEF and GTPase. (869 aa)
BCRBCR activator of RhoGEF and GTPase. (1064 aa)
MPP6Membrane palmitoylated protein 6; Belongs to the MAGUK family. (540 aa)
AKAP12A-kinase anchoring protein 12. (1782 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
NTNG2Netrin G2. (440 aa)
BSNBassoon presynaptic cytomatrix protein. (3726 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
FYNTyrosine-protein kinase. (537 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (546 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSCSAP00000013169ANF_receptor domain-containing protein. (317 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (878 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
ENSCSAP00000013783Uncharacterized protein. (140 aa)
DCCDCC netrin 1 receptor. (1420 aa)
MPP2Membrane palmitoylated protein 2; Belongs to the MAGUK family. (552 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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