STRINGSTRING
PTK2B PTK2B ITGB3 ITGB3 IFNL1 IFNL1 CD79B CD79B CACNG5 CACNG5 CACNG4 CACNG4 BMPR1B BMPR1B GRID2 GRID2 ENSCSAP00000000562 ENSCSAP00000000562 CHRNA10 CHRNA10 GRIN2C GRIN2C ENSCSAP00000001172 ENSCSAP00000001172 IL23A IL23A ITGA3 ITGA3 ERBB3 ERBB3 ITGA7 ITGA7 ITGA5 ITGA5 IL12RB1 IL12RB1 TRAF6 TRAF6 AMHR2 AMHR2 ITGB7 ITGB7 ITGAD ITGAD ITGAX ITGAX CHUK CHUK ITGAM ITGAM SHISA8 SHISA8 ACVR1B ACVR1B ITGAL ITGAL RAMP1 RAMP1 IL27RA IL27RA TRAT1 TRAT1 CHRNG CHRNG CHRND CHRND CACNG3 CACNG3 FLNA FLNA CHRNA7 CHRNA7 GPR156 GPR156 TYK2 TYK2 SYK SYK ITGB2 ITGB2 CSF2RB CSF2RB OLFM2 OLFM2 ITGB5 ITGB5 CACNG2 CACNG2 HFE HFE GABBR1 GABBR1 CNIH2 CNIH2 SHISA9 SHISA9 ENSCSAP00000004430 ENSCSAP00000004430 EPS8 EPS8 GRIN2B GRIN2B GRIN2A GRIN2A TFRC TFRC JAK2 JAK2 INSR INSR PMP22 PMP22 SHISA6 SHISA6 VWC2L VWC2L EMILIN1 EMILIN1 B2M B2M TGFBR2 TGFBR2 BMPR1A BMPR1A TSPAN32 TSPAN32 CNTFR CNTFR TRAF3 TRAF3 PTPN6 PTPN6 TF TF GRIA1 GRIA1 CD247 CD247 GABBR2 GABBR2 TGFBR1 TGFBR1 GRIN3A GRIN3A ITGB1 ITGB1 DLG3 DLG3 CHRNB1 CHRNB1 TGFB3 TGFB3 DLG4 DLG4 APBB1IP APBB1IP ABHD6 ABHD6 CALCRL CALCRL GRIN3B GRIN3B ITGAV ITGAV CALCR CALCR ITGA8 ITGA8 ITGA4 ITGA4 GP1BA GP1BA CHRNE CHRNE PORCN PORCN ITGA11 ITGA11 HTR3D HTR3D BMP2 BMP2 HTR3C HTR3C HTR3E HTR3E ITGB8 ITGB8 CSF2 CSF2 IL6 IL6 ITGA9 ITGA9 ACVR2B ACVR2B ENSCSAP00000010642 ENSCSAP00000010642 CHRNA1 CHRNA1 LYN LYN GRIK2 GRIK2 ITGA6 ITGA6 CD40 CD40 CHRNA6 CHRNA6 CHRNA5 CHRNA5 CHRNA3 CHRNA3 CHRNB4 CHRNB4 IKBKB IKBKB TRAF5 TRAF5 ITGB6 ITGB6 RAMP3 RAMP3 HTRA2 HTRA2 ACVR1 ACVR1 ACVR1C ACVR1C VWC2 VWC2 CHRNA2 CHRNA2 RNF31 RNF31 TRAF2 TRAF2 ACVR2A ACVR2A CNIH3 CNIH3 IL6ST IL6ST CD8A CD8A TRAV3 TRAV3 GRIN1 GRIN1 LIME1 LIME1 ITGA2 ITGA2 ITGA1 ITGA1 IGF1R IGF1R OSMR OSMR CHRNA9 CHRNA9 IL18RAP IL18RAP IL18R1 IL18R1 GRM1 GRM1 STXBP5 STXBP5 ZAP70 ZAP70 TFR2 TFR2 CSF2RA CSF2RA GRIA3 GRIA3 IL13RA1 IL13RA1 ITGA2B ITGA2B TGFB1 TGFB1 CD79A CD79A GRIK5 GRIK5 RAMP2 RAMP2 GRIA2 GRIA2 GRIA4 GRIA4 GRIN2D GRIN2D HTR3B HTR3B HTR3A HTR3A ERBB2 ERBB2 CD3E CD3E CD3D CD3D CD3G CD3G SKAP1 SKAP1 GRIK4 GRIK4 CPT1C CPT1C INSRR INSRR CHRNB2 CHRNB2 IL6R IL6R CACNG7 CACNG7 CACNG8 CACNG8 HJV HJV ITGA10 ITGA10 OLFM3 OLFM3 IL23R IL23R IFNLR1 IFNLR1 SDCBP SDCBP GP9 GP9 TLR6 TLR6 TLR1 TLR1 PGBD4 PGBD4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
IFNL1Interferon lambda 1. (202 aa)
CD79BCD79b molecule. (231 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (278 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (609 aa)
ENSCSAP00000000562ANF_receptor domain-containing protein. (332 aa)
CHRNA10Cholinergic receptor nicotinic alpha 10 subunit. (450 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1240 aa)
ENSCSAP00000001172Uncharacterized protein. (864 aa)
IL23AInterleukin 23 subunit alpha. (189 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1049 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1342 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (828 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
IL12RB1Interleukin 12 receptor subunit beta 1. (662 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ITGADVWFA domain-containing protein. (205 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1151 aa)
SHISA8Uncharacterized protein. (162 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
ITGALIntegrin subunit alpha L; Belongs to the integrin alpha chain family. (1168 aa)
RAMP1Receptor activity modifying protein 1. (148 aa)
IL27RAInterleukin 27 receptor subunit alpha. (556 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (187 aa)
CHRNGCholinergic receptor nicotinic gamma subunit. (516 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (514 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
FLNAFilamin A. (2639 aa)
CHRNA7Uncharacterized protein. (502 aa)
GPR156G protein-coupled receptor 156. (814 aa)
TYK2Tyrosine-protein kinase. (1184 aa)
SYKTyrosine-protein kinase. (635 aa)
ITGB2Integrin beta. (784 aa)
CSF2RBColony stimulating factor 2 receptor beta common subunit. (897 aa)
OLFM2Olfactomedin 2. (376 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (300 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (962 aa)
CNIH2Cornichon family AMPA receptor auxiliary protein 2. (193 aa)
SHISA9Uncharacterized protein. (190 aa)
ENSCSAP00000004430Uncharacterized protein. (165 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1402 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1327 aa)
TFRCTransferrin receptor. (774 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
INSRTyrosine-protein kinase receptor. (1385 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
SHISA6Uncharacterized protein. (220 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (174 aa)
EMILIN1Elastin microfibril interfacer 1. (860 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (320 aa)
CNTFRCiliary neurotrophic factor receptor. (372 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (811 aa)
CD247CD247 molecule. (165 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (941 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (922 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (724 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (429 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (606 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (472 aa)
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1042 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
ITGA8Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (628 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (493 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (511 aa)
ITGA11Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1188 aa)
HTR3D5-hydroxytryptamine receptor 3D. (458 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
HTR3C5-hydroxytryptamine receptor 3C; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (433 aa)
HTR3E5-hydroxytryptamine receptor 3E; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
CSF2Colony stimulating factor 2. (144 aa)
IL6Interleukin 6. (212 aa)
ITGA9Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (934 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
ENSCSAP00000010642Uncharacterized protein. (241 aa)
CHRNA1Neur_chan_LBD domain-containing protein. (248 aa)
LYNTyrosine-protein kinase. (512 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (859 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1073 aa)
CD40CD40 molecule. (278 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (494 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (468 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (456 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (563 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
RAMP3Receptor activity modifying protein 3. (201 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (530 aa)
RNF31Uncharacterized protein. (905 aa)
TRAF2TNF receptor-associated factor. (449 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
CNIH3Cornichon family AMPA receptor auxiliary protein 3. (160 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
CD8ACD8a molecule. (276 aa)
TRAV3T cell receptor alpha variable 3 (gene/pseudogene). (127 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
LIME1Uncharacterized protein. (315 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
OSMROncostatin M receptor. (977 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
IL18RAPInterleukin 18 receptor accessory protein. (598 aa)
IL18R1Interleukin 18 receptor 1. (539 aa)
GRM1G_PROTEIN_RECEP_F3_4 domain-containing protein. (878 aa)
STXBP5Syntaxin binding protein 5. (1116 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
TFR2Transferrin receptor 2. (798 aa)
CSF2RAColony stimulating factor 2 receptor alpha subunit. (403 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (425 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CD79ACD79a molecule. (199 aa)
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (980 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (811 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (441 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CD3ECD3e molecule. (197 aa)
CD3DCD3d molecule. (171 aa)
CD3GCD3g molecule. (209 aa)
SKAP1Src kinase associated phosphoprotein 1. (266 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (922 aa)
CPT1CCarnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (483 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (442 aa)
IL6RInterleukin 6 receptor. (443 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (421 aa)
HJVHemojuvelin BMP co-receptor. (425 aa)
ITGA10Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1167 aa)
OLFM3Olfactomedin 3. (445 aa)
IL23RInterleukin 23 receptor. (630 aa)
IFNLR1Interferon lambda receptor 1. (528 aa)
SDCBPUncharacterized protein. (293 aa)
GP9Glycoprotein IX platelet. (177 aa)
TLR6Toll-like receptor. (796 aa)
TLR1Toll like receptor 1; Belongs to the Toll-like receptor family. (786 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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