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| | POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) |
| | TWNK | Twinkle mtDNA helicase. (684 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (615 aa) |
| | XRCC6 | X-ray repair cross complementing 6. (609 aa) |
| | RAD51C | RAD51 paralog C. (367 aa) |
| | SRCAP | Uncharacterized protein. (3169 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (1248 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (236 aa) |
| | DNTT | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (550 aa) |
| | HELLS | Helicase, lymphoid specific. (713 aa) |
| | ENSCSAP00000002484 | Uncharacterized protein. (97 aa) |
| | SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) |
| | RAD51D | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (328 aa) |
| | LIG3 | DNA ligase. (1009 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (346 aa) |
| | ATAD5 | ATPase family AAA domain containing 5. (1838 aa) |
| | DNASE2 | Deoxyribonuclease 2, lysosomal. (251 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (280 aa) |
| | BTAF1 | B-TFIID TATA-box binding protein associated factor 1. (1519 aa) |
| | ENSCSAP00000002882 | Uncharacterized protein. (1547 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (340 aa) |
| | DKC1 | Dyskerin pseudouridine synthase 1. (514 aa) |
| | FAN1 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1016 aa) |
| | ENSCSAP00000003179 | Uncharacterized protein. (737 aa) |
| | MYO18A | Myosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2384 aa) |
| | POLQ | DNA polymerase theta. (2729 aa) |
| | WRNIP1 | WRN helicase interacting protein 1. (665 aa) |
| | DNMT1 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1061 aa) |
| | INO80 | INO80 complex ATPase subunit. (1556 aa) |
| | TDP2 | Tyrosyl-DNA phosphodiesterase 2. (358 aa) |
| | SUPV3L1 | Suv3 like RNA helicase. (787 aa) |
| | DDX1 | DEAD-box helicase 1. (740 aa) |
| | SMC6 | Structural maintenance of chromosomes 6. (1036 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (907 aa) |
| | RECQL | RecQ like helicase. (649 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1000 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (735 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | RECQL4 | RecQ like helicase 4. (1210 aa) |
| | C11orf80 | Chromosome 11 open reading frame 80. (524 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1058 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (738 aa) |
| | POLD4 | Uncharacterized protein. (107 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | DNMT3A | DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (723 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | ENSCSAP00000004852 | Uncharacterized protein. (195 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1473 aa) |
| | MSH5 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (850 aa) |
| | ENSCSAP00000005012 | DUF4550 domain-containing protein. (1104 aa) |
| | MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (572 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (949 aa) |
| | IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (993 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | TOP1MT | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (618 aa) |
| | N6AMT1 | N-6 adenine-specific DNA methyltransferase 1. (214 aa) |
| | EXO1 | Exonuclease 1. (845 aa) |
| | DDX11 | DEAD/H-box helicase 11. (906 aa) |
| | CHRAC1 | Chromatin accessibility complex subunit 1. (131 aa) |
| | PLD4 | Phospholipase D family member 4. (515 aa) |
| | TOP2B | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1621 aa) |
| | CEP41 | Centrosomal protein 41. (373 aa) |
| | HMGA1 | High mobility group AT-hook 1. (107 aa) |
| | XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (346 aa) |
| | APTX | Aprataxin. (356 aa) |
| | DNASE1 | Deoxyribonuclease; Belongs to the DNase I family. (288 aa) |
| | TATDN1 | TatD DNase domain containing 1. (281 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1494 aa) |
| | CHD4 | Uncharacterized protein. (1914 aa) |
| | PGBD5 | PiggyBac transposable element derived 5. (524 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (405 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa) |
| | DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (279 aa) |
| | ATRX | ATRX chromatin remodeler. (2459 aa) |
| | G3BP1 | G3BP stress granule assembly factor 1. (466 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (1965 aa) |
| | ERCC6L | ERCC excision repair 6 like, spindle assembly checkpoint helicase. (1254 aa) |
| | MEIOB | Meiosis specific with OB-fold. (472 aa) |
| | HLTF | Helicase like transcription factor. (1009 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (463 aa) |
| | MGME1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA- primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair; Belongs to the MGME1 family. (342 aa) |
| | DHX36 | DEAH-box helicase 36. (1007 aa) |
| | POLH | DNA polymerase eta. (712 aa) |
| | APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (518 aa) |
| | MLH3 | MutL homolog 3. (1237 aa) |
| | DNASE1L3 | Deoxyribonuclease 1 like 3. (165 aa) |
| | PMS1 | PMS1 homolog 1, mismatch repair system component. (931 aa) |
| | DNMT3B | DNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa) |
| | ARID3A | AT-rich interaction domain 3A. (498 aa) |
| | DHX9 | DExH-box helicase 9. (1126 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (641 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | EXD2 | Exonuclease 3'-5' domain containing 2. (636 aa) |
| | RAD51B | RAD51 paralog B. (265 aa) |
| | MPG | N-methylpurine DNA glycosylase. (279 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (840 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) |
| | FBH1 | F-box DNA helicase 1. (971 aa) |
| | TOP3B | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (862 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | CHD6 | Chromodomain helicase DNA binding protein 6. (2716 aa) |
| | RAD54L2 | RAD54 like 2. (1467 aa) |
| | MLH1 | MutL homolog 1. (756 aa) |
| | POLA1 | DNA polymerase. (1465 aa) |
| | CHD7 | Chromodomain helicase DNA binding protein 7. (2998 aa) |
| | NEIL1 | Nei like DNA glycosylase 1. (390 aa) |
| | ENDOG | Endonuclease. (299 aa) |
| | CECR2 | CECR2 histone acetyl-lysine reader. (1425 aa) |
| | EXOG | Exo/endonuclease G. (344 aa) |
| | ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2202 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | APLF | Aprataxin and PNKP like factor. (511 aa) |
| | SETX | Senataxin. (2679 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1125 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | FANCM | FA complementation group M. (2050 aa) |
| | CHD1 | Chromodomain helicase DNA binding protein 1. (1712 aa) |
| | POLK | DNA polymerase kappa. (847 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (397 aa) |
| | POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa) |
| | REV3L | REV3 like, DNA directed polymerase zeta catalytic subunit. (3128 aa) |
| | DQX1 | DEAQ-box RNA dependent ATPase 1. (717 aa) |
| | POLN | DNA polymerase nu. (663 aa) |
| | RAD17 | RAD17 checkpoint clamp loader component. (681 aa) |
| | HAUS3 | HAUS augmin like complex subunit 3. (603 aa) |
| | WRN | WRN RecQ like helicase. (1399 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1016 aa) |
| | RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1406 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2580 aa) |
| | LOC103231340 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) |
| | LOC103231340-2 | DNA-(apurinic or apyrimidinic site) lyase. (318 aa) |
| | TEP1 | Telomerase associated protein 1. (2624 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa) |
| | RFC1 | Replication factor C subunit 1. (985 aa) |
| | NEIL2 | Nei like DNA glycosylase 2. (332 aa) |
| | CHD2 | Uncharacterized protein. (1828 aa) |
| | BLM | BLM RecQ like helicase. (1423 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (280 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1683 aa) |
| | POLG | DNA polymerase gamma, catalytic subunit. (1228 aa) |
| | ISG20 | Interferon stimulated exonuclease gene 20. (181 aa) |
| | TERT | Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1132 aa) |
| | BIVM | Basic, immunoglobulin-like variable motif containing. (503 aa) |
| | METTL4 | Methyltransferase like 4; Belongs to the MT-A70-like family. (472 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (897 aa) |
| | DNASE1L1 | Deoxyribonuclease; Belongs to the DNase I family. (302 aa) |
| | PMS2 | PMS1 homolog 2, mismatch repair system component. (862 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | ALKBH4 | AlkB homolog 4, lysine demethylase. (302 aa) |
| | POLI | DNA polymerase iota. (672 aa) |
| | CHD1L | Chromodomain helicase DNA binding protein 1 like. (900 aa) |
| | ENSCSAP00000014590 | MTS domain-containing protein. (214 aa) |
| | SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (969 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | ENDOD1 | Endonuclease domain containing 1. (500 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa) |
| | NEIL3 | Nei like DNA glycosylase 3. (601 aa) |
| | TDG | Thymine DNA glycosylase. (267 aa) |
| | PRIMPOL | Primase and DNA directed polymerase. (556 aa) |
| | LIG1 | DNA ligase. (919 aa) |
| | ALKBH2 | AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase. (261 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (304 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | REXO2 | RNA exonuclease 2. (237 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa) |
| | ENDOV | Endonuclease V. (308 aa) |
| | POLD1 | DNA polymerase. (1086 aa) |
| | MPHOSPH9 | M-phase phosphoprotein 9. (1177 aa) |
| | EP400 | E1A binding protein p400. (3161 aa) |
| | ENSCSAP00000016160 | HSA domain-containing protein. (457 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa) |
| | TTF2 | Uncharacterized protein. (997 aa) |
| | DCLRE1B | DNA cross-link repair 1B. (532 aa) |
| | HFM1 | Helicase for meiosis 1. (874 aa) |
| | DNASE2B | Deoxyribonuclease 2 beta. (361 aa) |
| | MSH4 | MutS homolog 4. (935 aa) |
| | RAD54L | RAD54 like. (747 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (618 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (1954 aa) |
| | ENSCSAP00000017472 | ERCC4 domain-containing protein. (551 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | EXO5 | Exonuclease 5. (373 aa) |
| | PLD3 | Phospholipase D family member 3. (490 aa) |
| | ZGRF1 | Zinc finger GRF-type containing 1. (2109 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1441 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | POLG2 | DNA polymerase gamma 2, accessory subunit. (485 aa) |
| | SMARCAD1 | Uncharacterized protein. (840 aa) |
| | HELB | DNA helicase B. (1087 aa) |
| | ENSCSAP00000000740 | Uncharacterized protein. (88 aa) |
| | HELQ | Helicase, POLQ like. (1101 aa) |
| | MGMT | O-6-methylguanine-DNA methyltransferase. (164 aa) |
| | RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (991 aa) |
| | DCLRE1A | DNA cross-link repair 1A. (1040 aa) |
| | NAV2 | Neuron navigator 2. (2284 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1118 aa) |
| | FTO | FTO alpha-ketoglutarate dependent dioxygenase. (459 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2902 aa) |
| | TENT4B | Terminal nucleotidyltransferase 4B. (635 aa) |
| | SMUG1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1. (270 aa) |
| | NME1 | Nucleoside diphosphate kinase. (152 aa) |
| | ALKBH3 | AlkB homolog 3, alpha-ketoglutaratedependent dioxygenase. (283 aa) |
