STRINGSTRING
MEGF10 MEGF10 LEF1 LEF1 ROBO2 ROBO2 HNF1B HNF1B VDR VDR SCRIB SCRIB LRP5 LRP5 FGF4 FGF4 NKX2-5 NKX2-5 JAG2 JAG2 BAK1 BAK1 SLIT3 SLIT3 XKR7 XKR7 LRRC1 LRRC1 SIX3 SIX3 XKR9 XKR9 ATF2 ATF2 BMP7 BMP7 NOTCH1 NOTCH1 ENSCSAP00000012589 ENSCSAP00000012589 SLIT2 SLIT2 BCL2L11 BCL2L11 XKR6 XKR6 ENSCSAP00000012952 ENSCSAP00000012952 XKR5 XKR5 HAND2 HAND2 PPP2R1B PPP2R1B BAX BAX ZPR1 ZPR1 CHEK1 CHEK1 CCN1 CCN1 XKR8 XKR8 FOXC2 FOXC2 FZD5 FZD5 FOXC1 FOXC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MEGF10Multiple EGF like domains 10. (1140 aa)
LEF1Lymphoid enhancer binding factor 1. (331 aa)
ROBO2Roundabout guidance receptor 2. (1235 aa)
HNF1BHNF1 homeobox B. (557 aa)
VDRVitamin D receptor. (434 aa)
SCRIBScribble planar cell polarity protein. (1678 aa)
LRP5LDL receptor related protein 5. (1451 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
NKX2-5NK2 homeobox 5. (324 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
SLIT3Slit guidance ligand 3. (1320 aa)
XKR7XK-related protein. (579 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
SIX3SIX homeobox 3. (331 aa)
XKR9XK-related protein. (269 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
NOTCH1Notch receptor 1. (2555 aa)
ENSCSAP00000012589LRRNT domain-containing protein. (132 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
BCL2L11BCL2 like 11. (109 aa)
XKR6XK-related protein. (382 aa)
ENSCSAP00000012952XK-related protein. (285 aa)
XKR5XK-related protein. (684 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (599 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
ZPR1ZPR1 zinc finger. (459 aa)
CHEK1Checkpoint kinase 1. (749 aa)
CCN1Cellular communication network factor 1. (381 aa)
XKR8XK-related protein. (375 aa)
FOXC2Forkhead box C2. (501 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
FOXC1Forkhead box C1. (552 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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