STRINGSTRING
CXCL11 CXCL11 CXCL10 CXCL10 CXCL9 CXCL9 CALCA CALCA R3HDM2 R3HDM2 STAC3 STAC3 CX3CL1 CX3CL1 GSTO1 GSTO1 LACRT LACRT F2 F2 F2RL3 F2RL3 TMEM38A TMEM38A VMP1 VMP1 APLNR APLNR P2RX3 P2RX3 CORO1A CORO1A MS4A1 MS4A1 CACNB3 CACNB3 ATP2A1 ATP2A1 ENSCSAP00000002624 ENSCSAP00000002624 ENSCSAP00000002631 ENSCSAP00000002631 CLIC2 CLIC2 CDK5 CDK5 G6PD G6PD PLA2G6 PLA2G6 LOC103227224 LOC103227224 DRD3 DRD3 HPCAL1 HPCAL1 FMR1 FMR1 IAPP IAPP TMC1 TMC1 FKBP1B FKBP1B GRM6 GRM6 CAPN3 CAPN3 CABP4 CABP4 CABP2 CABP2 PPP3CB PPP3CB STAC STAC DRD1 DRD1 BAK1 BAK1 RYR2 RYR2 PTPN6 PTPN6 DHRS7C DHRS7C DRD4 DRD4 CAV3 CAV3 TMC2 TMC2 CAV1 CAV1 TRPC3 TRPC3 C4orf3 C4orf3 CRHR1 CRHR1 ENSCSAP00000000163 ENSCSAP00000000163 ANK2 ANK2 ITGB3 ITGB3 PPP3CA PPP3CA CACNG1 CACNG1 STIM1 STIM1 PKD2 PKD2 RRAD RRAD TSPAN13 TSPAN13 P2RX1 P2RX1 JPH1 JPH1 CALM2 CALM2 P2RX5 P2RX5 LHCGR LHCGR ENSCSAP00000009809 ENSCSAP00000009809 TOR2A TOR2A PLCG1 PLCG1 YWHAE YWHAE JPH2 JPH2 DMD DMD PML PML ENSCSAP00000010271 ENSCSAP00000010271 ASPH ASPH CHD7 CHD7 LYN LYN ATG5 ATG5 ABL1 ABL1 ADCYAP1R1 ADCYAP1R1 PPP3R1 PPP3R1 NPSR1 NPSR1 CEMIP CEMIP F2R F2R ENSCSAP00000011650 ENSCSAP00000011650 FYN FYN AKAP6 AKAP6 RAMP3 RAMP3 PRKD1 PRKD1 HTT HTT JPH4 JPH4 PTK2B PTK2B CACNB4 CACNB4 NTSR1 NTSR1 NIPSNAP2 NIPSNAP2 PDE4D PDE4D REM2 REM2 R3HDM1 R3HDM1 PSEN2 PSEN2 PPP3CC PPP3CC GRIN1 GRIN1 LIME1 LIME1 STIM2 STIM2 BIN1 BIN1 METTL21C METTL21C EPO EPO BCL2 BCL2 PDPK1 PDPK1 TGFB1 TGFB1 PLCG2 PLCG2 JPH3 JPH3 CYBA CYBA CALM3 CALM3 CABP5 CABP5 DRD2 DRD2 BAX BAX HRC HRC NOS1AP NOS1AP STAC2 STAC2 CACNB1 CACNB1 CASQ1 CASQ1 THY1 THY1 UBASH3B UBASH3B NOS1 NOS1 PLA2G1B PLA2G1B CABP1 CABP1 P2RX7 P2RX7 P2RX4 P2RX4 CACNG6 CACNG6 P2RX2 P2RX2 CASQ2 CASQ2 PTPN22 PTPN22 PDE4B PDE4B HPCA HPCA SLC9A1 SLC9A1 ENSCSAP00000017052 ENSCSAP00000017052 SELENON SELENON NPPA NPPA P2RY6 P2RY6 SLN SLN SMIM6 SMIM6 GJC2 GJC2 ENSCSAP00000017909 ENSCSAP00000017909 SUMO1 SUMO1 KCNE2 KCNE2 PRNP PRNP GPR35 GPR35 PLN PLN CALML5 CALML5 GPER1 GPER1 AKAP5 AKAP5 HSPA2 HSPA2 BDKRB1 BDKRB1 CRACR2A CRACR2A CXCR3 CXCR3 EHD3 EHD3 TRPC1 TRPC1 CACNA1C CACNA1C GNB5 GNB5 TMEM38B TMEM38B PIK3CG PIK3CG CALM1 CALM1 JSRP1 JSRP1 CACNA2D1 CACNA2D1 CBARP CBARP SLC8A1 SLC8A1 SRI SRI DIAPH1 DIAPH1 CACNB2 CACNB2 CALCR CALCR THADA THADA GEM GEM REM1 REM1 CACNA1F CACNA1F SESTD1 SESTD1 ENSCSAP00000009262 ENSCSAP00000009262 PRKCE PRKCE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CXCL11C-X-C motif chemokine. (83 aa)
CXCL10C-X-C motif chemokine. (98 aa)
CXCL9C-X-C motif chemokine ligand 9. (125 aa)
CALCACalcitonin related polypeptide alpha. (140 aa)
R3HDM2R3H domain containing 2. (1028 aa)
STAC3SH3 and cysteine rich domain 3. (364 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
GSTO1Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
LACRTLacritin. (137 aa)
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (596 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
TMEM38ATransmembrane protein 38A. (299 aa)
VMP1Vacuole membrane protein 1. (406 aa)
APLNRApelin receptor APJ; Belongs to the G-protein coupled receptor 1 family. (380 aa)
P2RX3Purinergic receptor P2X 3. (298 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
MS4A1Membrane spanning 4-domains A1. (297 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (994 aa)
ENSCSAP00000002624Uncharacterized protein. (279 aa)
ENSCSAP00000002631Ig-like domain-containing protein. (162 aa)
CLIC2Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (247 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
PLA2G6Phospholipase A2 group VI. (467 aa)
LOC103227224AIG1-type G domain-containing protein. (323 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (403 aa)
HPCAL1Hippocalcin like 1. (193 aa)
FMR1Fragile X mental retardation 1. (611 aa)
IAPPIslet amyloid polypeptide. (89 aa)
TMC1Transmembrane channel-like protein. (761 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
GRM6Glutamate metabotropic receptor 6. (877 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (824 aa)
CABP4Calcium binding protein 4. (274 aa)
CABP2Calcium binding protein 2. (201 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
STACSH3 and cysteine rich domain. (366 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (465 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
RYR2Ryanodine receptor 2. (4906 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
DHRS7CDehydrogenase/reductase 7C; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (394 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
TMC2Transmembrane channel-like protein. (879 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (876 aa)
C4orf3Chromosome 4 open reading frame 3. (199 aa)
CRHR1Corticotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 2 family. (415 aa)
ENSCSAP00000000163Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
ANK2Ankyrin 2. (4035 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
STIM1Stromal interaction molecule 1. (684 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (859 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
TSPAN13Tetraspanin 13; Belongs to the tetraspanin (TM4SF) family. (204 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
JPH1Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (661 aa)
CALM2Calmodulin 2. (149 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (396 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa)
ENSCSAP00000009809Uncharacterized protein. (268 aa)
TOR2ATorsin. (321 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (240 aa)
JPH2Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (696 aa)
DMDUncharacterized protein. (774 aa)
PMLPromyelocytic leukemia. (819 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
ASPHAspartate beta-hydroxylase. (744 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
LYNTyrosine-protein kinase. (512 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (496 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
NPSR1Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (284 aa)
CEMIPCell migration inducing hyaluronidase 1. (1376 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ENSCSAP00000011650Uncharacterized protein. (272 aa)
FYNTyrosine-protein kinase. (537 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
RAMP3Receptor activity modifying protein 3. (201 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (824 aa)
HTTHuntingtin. (3133 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (629 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (486 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (418 aa)
NIPSNAP2Nipsnap homolog 2. (146 aa)
PDE4DPhosphodiesterase. (641 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
R3HDM1R3H domain containing 1. (1134 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
PPP3CCProtein phosphatase 3 catalytic subunit gamma. (509 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
LIME1Uncharacterized protein. (315 aa)
STIM2Stromal interaction molecule 2. (832 aa)
BIN1Bridging integrator 1. (608 aa)
METTL21CMethyltransferase like 21C. (264 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (193 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (748 aa)
CYBACytochrome b-245 alpha chain. (197 aa)
CALM3Calmodulin 3. (149 aa)
CABP5Calcium binding protein 5. (152 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
HRCHistidine rich calcium binding protein. (788 aa)
NOS1APPID domain-containing protein. (690 aa)
STAC2SH3 and cysteine rich domain 2. (411 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
THY1Thy-1 cell surface antigen. (161 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
NOS1Nitric oxide synthase 1. (768 aa)
PLA2G1BPhospholipase A(2). (148 aa)
CABP1Uncharacterized protein. (227 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (491 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (358 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (470 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
PDE4BPhosphodiesterase. (517 aa)
HPCAHippocalcin. (193 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (815 aa)
ENSCSAP00000017052Uncharacterized protein. (42 aa)
SELENONEF-hand domain-containing protein. (432 aa)
NPPANatriuretic peptide A. (153 aa)
P2RY6Pyrimidinergic receptor P2Y6. (328 aa)
SLNSarcolipin. (31 aa)
SMIM6Small integral membrane protein 6. (62 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (441 aa)
ENSCSAP00000017909Uncharacterized protein; Belongs to the GST superfamily. (241 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
PRNPMajor prion protein; Belongs to the prion family. (245 aa)
GPR35G protein-coupled receptor 35; Belongs to the G-protein coupled receptor 1 family. (309 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
CALML5Calmodulin like 5. (146 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (639 aa)
BDKRB1Bradykinin receptor B1. (353 aa)
CRACR2ACalcium release activated channel regulator 2A. (734 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
GNB5G protein subunit beta 5. (353 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
JSRP1Junctional sarcoplasmic reticulum protein 1. (328 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
CBARPCACN subunit beta associated regulatory protein. (628 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (632 aa)
SRISorcin. (183 aa)
DIAPH1Diaphanous related formin 1. (1243 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (488 aa)
THADATHADA armadillo repeat containing. (1803 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
CACNA1FIon_trans domain-containing protein. (233 aa)
SESTD1SEC14 and spectrin domain containing 1. (696 aa)
ENSCSAP00000009262Uncharacterized protein. (115 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (18%) [HD]