STRINGSTRING
TLR4 TLR4 BCL2L2 BCL2L2 GJA1 GJA1 PARP1 PARP1 BCL2L11 BCL2L11 IGF1R IGF1R GRM5 GRM5 ATP1A3 ATP1A3 IGF1 IGF1 CASP4 CASP4 BACE1 BACE1 CACNB1 CACNB1 NGFR NGFR VCAM1 VCAM1 EPHB2 EPHB2 PRNP PRNP ADRB2 ADRB2 CACNA1A CACNA1A LRP1 LRP1 CDK5 CDK5 GSK3B GSK3B EPHA4 EPHA4 APP APP FN1 FN1 AGER AGER TREM2 TREM2 LGMN LGMN CD36 CD36 CACNA2D1 CACNA2D1 PSEN1 PSEN1 ITGA4 ITGA4 FYN FYN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
BCL2L2BCL2 like 2. (193 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
PARP1Poly(ADP-ribose) polymerase 1. (709 aa)
BCL2L11BCL2 like 11. (109 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
GRM5Glutamate metabotropic receptor 5. (729 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1013 aa)
IGF1Insulin like growth factor 1. (159 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
BACE1Beta-secretase 1; Belongs to the peptidase A1 family. (501 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
NGFRNerve growth factor receptor. (427 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
EPHB2EPH receptor B2. (975 aa)
PRNPMajor prion protein; Belongs to the prion family. (245 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1363 aa)
LRP1LDL receptor related protein 1. (4544 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
EPHA4EPH receptor A4. (986 aa)
APPAmyloid beta precursor protein. (770 aa)
FN1Fibronectin 1. (2265 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (260 aa)
LGMNLegumain. (433 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
PSEN1Presenilin 1. (467 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
FYNTyrosine-protein kinase. (537 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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