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TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) | ||||
PAX6 | Paired box 6. (436 aa) | ||||
NF1 | Neurofibromin 1. (2849 aa) | ||||
SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (513 aa) | ||||
GATA2 | GATA binding protein 2. (397 aa) | ||||
PTN | Pleiotrophin. (168 aa) | ||||
BTG2 | BTG anti-proliferation factor 2. (158 aa) | ||||
NR2E1 | Nuclear receptor subfamily 2 group E member 1. (385 aa) | ||||
PROX1 | Prospero homeobox 1. (737 aa) | ||||
LIMS2 | LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa) | ||||
SLC16A2 | Solute carrier family 16 member 2. (537 aa) | ||||
KIFAP3 | Kinesin associated protein 3. (794 aa) | ||||
WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) | ||||
CTNNA1 | Catenin alpha 1. (906 aa) | ||||
ENSCSAP00000019086 | Uncharacterized protein. (141 aa) | ||||
VAX1 | Ventral anterior homeobox 1. (333 aa) | ||||
CEND1 | Cell cycle exit and neuronal differentiation 1. (152 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) | ||||
KDM2B | Lysine demethylase 2B. (1348 aa) |