STRINGSTRING
EPB41 EPB41 WAS WAS ACTN1 ACTN1 TMEM110 TMEM110 ENSCSAP00000009262 ENSCSAP00000009262 PFN1 PFN1 CALB1 CALB1 ERC2 ERC2 ECT2 ECT2 PPP1R9A PPP1R9A PLEKHH2 PLEKHH2 EZR EZR HAAO HAAO MAPRE1 MAPRE1 FGF1 FGF1 FLNB FLNB DLG4 DLG4 SPINK5 SPINK5 RIMS2 RIMS2 NEDD4 NEDD4 SEPTIN5 SEPTIN5 BFSP1 BFSP1 ERC1 ERC1 UNC13C UNC13C PARD3 PARD3 PLS1 PLS1 SELE SELE RASSF4 RASSF4 CTTNBP2 CTTNBP2 MELK MELK CLTA CLTA MYH10 MYH10 CAPN9 CAPN9 ARV1 ARV1 UNC13B UNC13B WASL WASL EXOC3L4 EXOC3L4 TNFAIP2 TNFAIP2 SLA SLA ACTN2 ACTN2 MKLN1 MKLN1 FMN2 FMN2 KMO KMO EXOC4 EXOC4 CLASP2 CLASP2 CTTN CTTN CLTB CLTB TRIP10 TRIP10 SEPTIN12 SEPTIN12 DBN1 DBN1 PFN4 PFN4 ACTN3 ACTN3 EPS8 EPS8 LLGL1 LLGL1 GYS2 GYS2 MYH9 MYH9 C2CD5 C2CD5 PVALB PVALB SSPN SSPN NEDD9 NEDD9 ANK3 ANK3 CASR CASR HCLS1 HCLS1 EXOC2 EXOC2 CDR2 CDR2 SPATA3 SPATA3 PHLDB2 PHLDB2 EXOC6 EXOC6 GIPC1 GIPC1 TBC1D10B TBC1D10B SEPTIN1 SEPTIN1 SEPTIN3 SEPTIN3 MYO9B MYO9B UNC13A UNC13A TRAF6 TRAF6 ACTR1A ACTR1A SEPTIN9 SEPTIN9 EXOC1 EXOC1 EXOC7 EXOC7 INSC INSC FGFR2 FGFR2 SEPTIN11 SEPTIN11 WEE1 WEE1 ARFIP2 ARFIP2 STIM1 STIM1 NUMA1 NUMA1 OSBPL8 OSBPL8 EXOC3L1 EXOC3L1 AKT2 AKT2 FMNL1 FMNL1 EXOC8 EXOC8 SPRR4 SPRR4 NAP1L3 NAP1L3 FAM110C FAM110C PRKCZ PRKCZ CNKSR1 CNKSR1 RIMS3 RIMS3 KNCN KNCN FNBP1L FNBP1L GPSM2 GPSM2 JTB JTB RIMBP2 RIMBP2 PXN PXN SPTA1 SPTA1 C2CD2L C2CD2L PHLDB1 PHLDB1 LASP1 LASP1 SPIRE2 SPIRE2 RDX RDX KRT19 KRT19 EXOC3L2 EXOC3L2 TDO2 TDO2 PHLDB3 PHLDB3 SLC4A1 SLC4A1 ENSCSAP00000014408 ENSCSAP00000014408 SEPTIN6 SEPTIN6 MYO5B MYO5B LANCL3 LANCL3 TRPC4 TRPC4 SPIRE1 SPIRE1 EXOC3 EXOC3 AKAP13 AKAP13 UTRN UTRN SEPTIN10 SEPTIN10 GYPC GYPC ENSCSAP00000012858 ENSCSAP00000012858 NIM1K NIM1K NSMF NSMF CLASP1 CLASP1 EPB41L2 EPB41L2 SAPCD2 SAPCD2 KYNU KYNU SEPTIN14 SEPTIN14 LANCL2 LANCL2 COBL COBL PTK2B PTK2B ARL6IP6 ARL6IP6 CYTIP CYTIP CD302 CD302 STXBP6 STXBP6 GRK4 GRK4 CFL2 CFL2 CTSZ CTSZ RTKN RTKN DCTN1 DCTN1 DBNL DBNL EXOC6B EXOC6B FER FER RHOA RHOA ANK1 ANK1 ANLN ANLN CIB2 CIB2 FNBP1 FNBP1 EXOC5 EXOC5 SPTAN1 SPTAN1 ENSCSAP00000010271 ENSCSAP00000010271 DMD DMD OOEP OOEP KHDC3L KHDC3L RIMS1 RIMS1 SPTBN1 SPTBN1 ENSCSAP00000009938 ENSCSAP00000009938 PPP1R36 PPP1R36 SHPK SHPK SPTB SPTB GSN GSN MYADM MYADM TMEM250 TMEM250
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPB41Erythrocyte membrane protein band 4.1. (667 aa)
WASWASP actin nucleation promoting factor. (502 aa)
ACTN1Actinin alpha 1. (914 aa)
TMEM110Uncharacterized protein. (327 aa)
ENSCSAP00000009262Uncharacterized protein. (115 aa)
PFN1Profilin; Belongs to the profilin family. (140 aa)
CALB1Calbindin 1. (261 aa)
ERC2ELKS/RAB6-interacting/CAST family member 2. (953 aa)
ECT2Epithelial cell transforming 2. (914 aa)
PPP1R9AProtein phosphatase 1 regulatory subunit 9A. (1321 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1493 aa)
EZREzrin. (584 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (300 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (268 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FLNBFilamin B. (2602 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1093 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1689 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
SEPTIN5Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (369 aa)
BFSP1Beaded filament structural protein 1. (423 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
UNC13CUnc-13 homolog C. (1150 aa)
PARD3Par-3 family cell polarity regulator. (1218 aa)
PLS1Plastin 1. (629 aa)
SELESelectin E. (610 aa)
RASSF4Ras association domain family member 4. (321 aa)
CTTNBP2Cortactin binding protein 2. (1621 aa)
MELKNon-specific serine/threonine protein kinase. (651 aa)
CLTAClathrin light chain A. (218 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
CAPN9Calpain 9; Belongs to the peptidase C2 family. (693 aa)
ARV1ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
UNC13BUnc-13 homolog B. (1610 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
EXOC3L4Exocyst complex component 3 like 4. (745 aa)
TNFAIP2TNF alpha induced protein 2. (740 aa)
SLASrc like adaptor. (276 aa)
ACTN2Actinin alpha 2. (894 aa)
MKLN1Muskelin 1. (643 aa)
FMN2Formin 2. (1573 aa)
KMOKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. (486 aa)
EXOC4Exocyst complex component 4. (505 aa)
CLASP2Uncharacterized protein. (1552 aa)
CTTNCortactin. (550 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
TRIP10Thyroid hormone receptor interactor 10. (545 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (363 aa)
DBN1Drebrin 1. (695 aa)
PFN4Profilin; Belongs to the profilin family. (129 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (822 aa)
LLGL1LLGL scribble cell polarity complex component 1. (1064 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
C2CD5C2 calcium dependent domain containing 5. (1073 aa)
PVALBParvalbumin; Belongs to the parvalbumin family. (110 aa)
SSPNSarcospan. (243 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
ANK3Ankyrin 3. (2797 aa)
CASRCalcium sensing receptor. (882 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (497 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (904 aa)
CDR2Cerebellar degeneration related protein 2. (454 aa)
SPATA3Spermatogenesis associated 3. (192 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1348 aa)
EXOC6Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (843 aa)
GIPC1GIPC PDZ domain containing family member 1. (333 aa)
TBC1D10BTBC1 domain family member 10B. (815 aa)
SEPTIN1Septin 1. (372 aa)
SEPTIN3Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2023 aa)
UNC13AUnc-13 homolog A. (1710 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
ACTR1AActin related protein 1A. (376 aa)
SEPTIN9Septin 9; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (568 aa)
EXOC1Exocyst complex component 1. (901 aa)
EXOC7Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (720 aa)
INSCINSC spindle orientation adaptor protein. (579 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
SEPTIN11Septin 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
WEE1Wee1-like protein kinase. (646 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (341 aa)
STIM1Stromal interaction molecule 1. (684 aa)
NUMA1Nuclear mitotic apparatus protein 1. (2118 aa)
OSBPL8Oxysterol-binding protein; Belongs to the OSBP family. (925 aa)
EXOC3L1Exocyst complex component 3 like 1. (746 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
FMNL1Formin like 1. (1095 aa)
EXOC8Exocyst complex component 8. (725 aa)
SPRR4Small proline rich protein 4. (78 aa)
NAP1L3Nucleosome assembly protein 1 like 3; Belongs to the nucleosome assembly protein (NAP) family. (507 aa)
FAM110CFamily with sequence similarity 110 member C. (321 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (720 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (308 aa)
KNCNKinocilin. (101 aa)
FNBP1LFormin binding protein 1 like. (547 aa)
GPSM2G protein signaling modulator 2. (685 aa)
JTBJumping translocation breakpoint. (146 aa)
RIMBP2RIMS binding protein 2. (901 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2421 aa)
C2CD2LC2CD2 like. (706 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1296 aa)
LASP1LIM and SH3 protein 1. (261 aa)
SPIRE2Spire type actin nucleation factor 2. (583 aa)
RDXRadixin. (605 aa)
KRT19Keratin 19; Belongs to the intermediate filament family. (400 aa)
EXOC3L2Exocyst complex component 3 like 2. (409 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
PHLDB3PH domain-containing protein. (172 aa)
SLC4A1Anion exchange protein. (924 aa)
ENSCSAP00000014408Rho-GAP domain-containing protein. (860 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (427 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1823 aa)
LANCL3LanC like 3. (414 aa)
TRPC4ANK_REP_REGION domain-containing protein. (395 aa)
SPIRE1Spire type actin nucleation factor 1. (656 aa)
EXOC3Exocyst complex component 3. (745 aa)
AKAP13A-kinase anchoring protein 13. (2854 aa)
UTRNUtrophin. (3434 aa)
SEPTIN10Septin 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (454 aa)
GYPCGlycophorin C (Gerbich blood group). (117 aa)
ENSCSAP00000012858START domain-containing protein. (1078 aa)
NIM1KNIM1 serine/threonine protein kinase. (436 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (530 aa)
CLASP1Cytoplasmic linker associated protein 1. (1528 aa)
EPB41L2Erythrocyte membrane protein band 4.1 like 2. (825 aa)
SAPCD2Suppressor APC domain containing 2. (395 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
SEPTIN14Septin 14; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (383 aa)
LANCL2LanC like 2. (450 aa)
COBLCordon-bleu WH2 repeat protein. (1302 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
ARL6IP6ADP ribosylation factor like GTPase 6 interacting protein 6. (259 aa)
CYTIPCytohesin 1 interacting protein. (340 aa)
CD302C-type lectin domain-containing protein. (232 aa)
STXBP6Syntaxin binding protein 6. (210 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (572 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
RTKNRhotekin. (550 aa)
DCTN1CAP-Gly domain-containing protein. (1433 aa)
DBNLDrebrin like. (436 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (755 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
RHOARas homolog family member A. (193 aa)
ANK1Ankyrin 1. (1920 aa)
ANLNAnillin actin binding protein. (1145 aa)
CIB2Calcium and integrin binding family member 2. (187 aa)
FNBP1Formin binding protein 1. (647 aa)
EXOC5Exocyst complex component 5. (708 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2477 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
DMDUncharacterized protein. (774 aa)
OOEPOocyte expressed protein. (149 aa)
KHDC3LKH domain containing 3 like, subcortical maternal complex member. (229 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1573 aa)
SPTBN1Spectrin beta chain; Belongs to the spectrin family. (2364 aa)
ENSCSAP00000009938Uncharacterized protein. (45 aa)
PPP1R36Protein phosphatase 1 regulatory subunit 36. (289 aa)
SHPKFGGY_N domain-containing protein. (482 aa)
SPTBSpectrin beta chain; Belongs to the spectrin family. (2138 aa)
GSNGelsolin. (781 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
TMEM250Transmembrane protein 250. (139 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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