STRINGSTRING
RFC4 RFC4 ATAD2B ATAD2B WRNIP1 WRNIP1 ATAD5 ATAD5 IQCA1 IQCA1 PSMC3 PSMC3 LONP2 LONP2 CLPB CLPB VPS4A VPS4A PSMC5 PSMC5 PSMC4 PSMC4 NSF NSF SPATA5 SPATA5 FIGNL1 FIGNL1 PSMC1 PSMC1 ATAD3A ATAD3A ORC1 ORC1 RFC5 RFC5 CDC6 CDC6 SPG7 SPG7 RFC2 RFC2 VPS4B VPS4B KATNAL2 KATNAL2 KATNAL1 KATNAL1 AFG3L2 AFG3L2 TRIP13 TRIP13 KATNA1 KATNA1 RFC1 RFC1 NVL NVL FIGN FIGN PSMC6 PSMC6 CLPX CLPX PEX1 PEX1 CHTF18 CHTF18 YME1L1 YME1L1 PSMC2 PSMC2 PEX6 PEX6 SPAST SPAST ATAD2 ATAD2 SPATA5L1 SPATA5L1 VCP VCP LONP1 LONP1 BCS1L BCS1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RFC4Replication factor C subunit 4. (363 aa)
ATAD2BATPase family AAA domain containing 2B. (1458 aa)
WRNIP1WRN helicase interacting protein 1. (665 aa)
ATAD5ATPase family AAA domain containing 5. (1838 aa)
IQCA1IQ motif containing with AAA domain 1. (827 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (843 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (677 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (769 aa)
SPATA5Uncharacterized protein. (789 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (674 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ATAD3AATPase family AAA domain containing 3A. (405 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
RFC5Replication factor C subunit 5. (340 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (799 aa)
RFC2Replication factor C subunit 2. (353 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (535 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (708 aa)
TRIP13Thyroid hormone receptor interactor 13. (432 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (422 aa)
RFC1Replication factor C subunit 1. (985 aa)
NVLNuclear VCP like. (856 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (633 aa)
PEX1Peroxisomal biogenesis factor 1. (1283 aa)
CHTF18Chromosome transmission fidelity factor 18. (976 aa)
YME1L1YME1 like 1 ATPase. (767 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PEX6Peroxisomal biogenesis factor 6. (980 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (614 aa)
ATAD2ATPase family AAA domain containing 2. (1386 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (961 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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