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VPS4A VPS4A VCP VCP SPATA5L1 SPATA5L1 ATAD2 ATAD2 SPAST SPAST PEX6 PEX6 PSMC2 PSMC2 YME1L1 YME1L1 PEX1 PEX1 PSMC6 PSMC6 FIGN FIGN NVL NVL KATNA1 KATNA1 TRIP13 TRIP13 AFG3L2 AFG3L2 KATNAL1 KATNAL1 VPS4B VPS4B PSMC1 PSMC1 FIGNL1 FIGNL1 BCS1L BCS1L ATAD2B ATAD2B SPATA5 SPATA5 NSF NSF PSMC4 PSMC4 PSMC5 PSMC5 PSMC3 PSMC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
ATAD2ATPase family AAA domain containing 2. (1386 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (614 aa)
PEX6Peroxisomal biogenesis factor 6. (980 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
YME1L1YME1 like 1 ATPase. (767 aa)
PEX1Peroxisomal biogenesis factor 1. (1283 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (759 aa)
NVLNuclear VCP like. (856 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (422 aa)
TRIP13Thyroid hormone receptor interactor 13. (432 aa)
AFG3L2AFG3 like matrix AAA peptidase subunit 2. (708 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (674 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
ATAD2BATPase family AAA domain containing 2B. (1458 aa)
SPATA5Uncharacterized protein. (789 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (769 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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