STRINGSTRING
CSDE1 CSDE1 YBX1 YBX1 YARS1 YARS1 ZCCHC17 ZCCHC17 RPA2 RPA2 LIN28A LIN28A ENSCSAP00000017615 ENSCSAP00000017615 LIG4 LIG4 RPS28 RPS28 ENSCSAP00000018451 ENSCSAP00000018451 PSMC1 PSMC1 ENSCSAP00000018803 ENSCSAP00000018803 ENSCSAP00000018943 ENSCSAP00000018943 ENSCSAP00000018974 ENSCSAP00000018974 AIMP1 AIMP1 DIS3L2 DIS3L2 LIG3 LIG3 EXOSC1 EXOSC1 POLR3H POLR3H CSDC2 CSDC2 PDCD11 PDCD11 KARS1 KARS1 DDIAS DDIAS PSMC4 PSMC4 NARS2 NARS2 STN1 STN1 NABP2 NABP2 TEN1 TEN1 PSMC5 PSMC5 MRPS12 MRPS12 POLR2G POLR2G SUPT6H SUPT6H ENSCSAP00000003724 ENSCSAP00000003724 CCAR1 CCAR1 EIF1AD EIF1AD SSBP1 SSBP1 MCM5 MCM5 RPL8 RPL8 RMI2 RMI2 MCM2 MCM2 YBX3 YBX3 RADX RADX POT1 POT1 EXOSC3 EXOSC3 MEIOB MEIOB MRPL2 MRPL2 PSMC2 PSMC2 DARS2 DARS2 EIF5A EIF5A YBX2 YBX2 NABP1 NABP1 EIF5A2 EIF5A2 MCM3 MCM3 TTC14 TTC14 RPA3 RPA3 DIS3L DIS3L MCM10 MCM10 EIF2S1 EIF2S1 SRBD1 SRBD1 MCM8 MCM8 POLR2H POLR2H RPA1 RPA1 PNPT1 PNPT1 EIF1AX EIF1AX LIN28B LIN28B EXOSC2 EXOSC2 MCM4 MCM4 RPS23 RPS23 PSMC6 PSMC6 MCM9 MCM9 MRPS17 MRPS17 DARS1 DARS1 MCM6 MCM6 HELZ2 HELZ2 ENSCSAP00000012872 ENSCSAP00000012872 RNGTT RNGTT DIS3 DIS3 MCM7 MCM7 NARS1 NARS1 BRCA2 BRCA2 EIF1AY EIF1AY DHX8 DHX8 ENSCSAP00000014778 ENSCSAP00000014778 LIG1 LIG1 RPS11 RPS11 AIM2 AIM2 IFI16 IFI16 PYHIN1 PYHIN1 MNDA MNDA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSDE1Cold shock domain containing E1. (844 aa)
YBX1Y-box binding protein 1. (255 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (241 aa)
RPA2Replication protein A2. (270 aa)
LIN28ALin-28 homolog A. (210 aa)
ENSCSAP00000017615Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (158 aa)
LIG4DNA ligase. (911 aa)
RPS28Uncharacterized protein. (68 aa)
ENSCSAP00000018451Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000018803CSP domain-containing protein. (147 aa)
ENSCSAP00000018943Ribosomal_L2_C domain-containing protein. (257 aa)
ENSCSAP00000018974Uncharacterized protein. (130 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (411 aa)
DIS3L2DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (918 aa)
LIG3DNA ligase. (1009 aa)
EXOSC1Exosome component 1. (195 aa)
POLR3HRNA polymerase III subunit H. (237 aa)
CSDC2Cold shock domain containing C2. (153 aa)
PDCD11Programmed cell death 11. (1871 aa)
KARS1Lysine--tRNA ligase. (625 aa)
DDIASDNA damage induced apoptosis suppressor. (1001 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NARS2Asparaginyl-tRNA synthetase 2, mitochondrial. (421 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)
NABP2Nucleic acid binding protein 2. (211 aa)
TEN1Uncharacterized protein. (94 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
MRPS12Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family. (139 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1580 aa)
ENSCSAP00000003724Ribosomal_L2_C domain-containing protein. (185 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1150 aa)
EIF1ADEukaryotic translation initiation factor 1A domain containing. (165 aa)
SSBP1Single stranded DNA binding protein 1. (148 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
RPL8Ribosomal protein L8. (257 aa)
RMI2RecQ mediated genome instability 2. (147 aa)
MCM2DNA helicase; Belongs to the MCM family. (738 aa)
YBX3Y-box binding protein 3. (373 aa)
RADXRPA1 related single stranded DNA binding protein, X-linked. (855 aa)
POT1Protection of telomeres 1. (634 aa)
EXOSC3Exosome component 3. (275 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
MRPL2Mitochondrial ribosomal protein L2. (305 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (645 aa)
EIF5AeIF-5a domain-containing protein. (210 aa)
YBX2Y-box binding protein 2. (359 aa)
NABP1Nucleic acid binding protein 1. (204 aa)
EIF5A2Eukaryotic translation initiation factor 5A. (153 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
TTC14Tetratricopeptide repeat domain 14. (771 aa)
RPA3Replication protein A3. (121 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (971 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (874 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
SRBD1S1 RNA binding domain 1. (994 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (840 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
EIF1AXEukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
LIN28BLin-28 homolog B. (208 aa)
EXOSC2Exosome component 2. (293 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
RPS23Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
MRPS17Uncharacterized protein. (130 aa)
DARS1Aspartyl-tRNA synthetase. (501 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
HELZ2Helicase with zinc finger 2. (2822 aa)
ENSCSAP00000012872Ribosomal_S17_N domain-containing protein. (197 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
NARS1Asparaginyl-tRNA synthetase. (558 aa)
BRCA2BRCA2 DNA repair associated. (3420 aa)
EIF1AYEukaryotic translation initiation factor 1A Y-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
DHX8DEAH-box helicase 8. (1223 aa)
ENSCSAP00000014778RPA_C domain-containing protein. (256 aa)
LIG1DNA ligase. (919 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
AIM2Absent in melanoma 2. (343 aa)
IFI16Interferon gamma inducible protein 16. (728 aa)
PYHIN1Pyrin and HIN domain family member 1. (492 aa)
MNDAMyeloid cell nuclear differentiation antigen. (407 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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