STRINGSTRING
KRBA2 KRBA2 ESRP2 ESRP2 PAN2 PAN2 TIGD1 TIGD1 TEFM TEFM RNASEH2A RNASEH2A RNASEH1 RNASEH1 POLQ POLQ REXO5 REXO5 ERI2 ERI2 EXD3 EXD3 CNOT7 CNOT7 ERI1 ERI1 ISG20 ISG20 AEN AEN PIWIL4 PIWIL4 ENSCSAP00000015264 ENSCSAP00000015264 REXO2 REXO2 POLD1 POLD1 ISG20L2 ISG20L2 PIWIL1 PIWIL1 POLE POLE TOE1 TOE1 ERI3 ERI3 AGO3 AGO3 AGO1 AGO1 AGO4 AGO4 EXOSC10 EXOSC10 JRKL JRKL PARN PARN AGO2 AGO2 PIWIL3 PIWIL3 CNOT8 CNOT8 SETMAR SETMAR REXO1 REXO1 PNLDC1 PNLDC1 ESRP1 ESRP1 EXD2 EXD2 POLA1 POLA1 GIN1 GIN1 EXD1 EXD1 REXO4 REXO4 REV3L REV3L POLN POLN WRN WRN NYNRIN NYNRIN PIWIL2 PIWIL2 ZBED9 ZBED9 ENSCSAP00000018116 ENSCSAP00000018116
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRBA2KRAB-A domain containing 2. (492 aa)
ESRP2Epithelial splicing regulatory protein 2. (715 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1202 aa)
TIGD1Tigger transposable element derived 1. (592 aa)
TEFMTranscription elongation factor, mitochondrial. (361 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (300 aa)
RNASEH1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (286 aa)
POLQDNA polymerase theta. (2729 aa)
REXO5RNA exonuclease 5. (772 aa)
ERI2ERI1 exoribonuclease family member 2. (691 aa)
EXD3Exonuclease 3'-5' domain containing 3. (875 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
ERI1Exoribonuclease 1. (349 aa)
ISG20Interferon stimulated exonuclease gene 20. (181 aa)
AENApoptosis enhancing nuclease. (325 aa)
PIWIL4Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family. (852 aa)
ENSCSAP00000015264Exonuclease domain-containing protein. (330 aa)
REXO2RNA exonuclease 2. (237 aa)
POLD1DNA polymerase. (1086 aa)
ISG20L2Interferon stimulated exonuclease gene 20 like 2. (353 aa)
PIWIL1Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (861 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
TOE1Target of EGR1, exonuclease. (509 aa)
ERI3ERI1 exoribonuclease family member 3. (337 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
EXOSC10Exosome component 10. (884 aa)
JRKLJRK like. (524 aa)
PARNPoly(A)-specific ribonuclease. (639 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (904 aa)
PIWIL3Piwi like RNA-mediated gene silencing 3; Belongs to the argonaute family. (870 aa)
CNOT8CCR4-NOT transcription complex subunit 8. (292 aa)
SETMARSET domain and mariner transposase fusion gene. (684 aa)
REXO1RNA exonuclease 1 homolog. (1218 aa)
PNLDC1PARN like, ribonuclease domain containing 1. (522 aa)
ESRP1Epithelial splicing regulatory protein 1. (663 aa)
EXD2Exonuclease 3'-5' domain containing 2. (636 aa)
POLA1DNA polymerase. (1465 aa)
GIN1Gypsy retrotransposon integrase 1. (522 aa)
EXD1Exonuclease 3'-5' domain containing 1. (513 aa)
REXO4REX4 homolog, 3'-5' exonuclease. (422 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (3128 aa)
POLNDNA polymerase nu. (663 aa)
WRNWRN RecQ like helicase. (1399 aa)
NYNRINNYN domain and retroviral integrase containing. (1898 aa)
PIWIL2Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (973 aa)
ZBED9Uncharacterized protein. (691 aa)
ENSCSAP00000018116Exonuclease domain-containing protein. (599 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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