STRINGSTRING
ENSCSAP00000011392 ENSCSAP00000011392 CCT4 CCT4 TCP1 TCP1 TIMM13 TIMM13 ENSCSAP00000007626 ENSCSAP00000007626 TIMM8A TIMM8A CCT8 CCT8 PSMG1 PSMG1 CANX CANX LOC103219534 LOC103219534 CALR CALR SDHAF2 SDHAF2 CCT6B CCT6B CALR3 CALR3 RSAD1 RSAD1 CCT2 CCT2 CCT8L2 CCT8L2 ENSCSAP00000017870 ENSCSAP00000017870 ENSCSAP00000017740 ENSCSAP00000017740 CCT3 CCT3 TIMM8B TIMM8B CRYAB CRYAB CLGN CLGN ENSCSAP00000014307 ENSCSAP00000014307 PSMG2 PSMG2 MDN1 MDN1 CCT6A CCT6A GRPEL1 GRPEL1 CCT7 CCT7 PFDN4 PFDN4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSAP00000011392Tubulin-specific chaperone A; Belongs to the TBCA family. (60 aa)
CCT4T-complex protein 1 subunit delta. (539 aa)
TCP1T-complex 1. (556 aa)
TIMM13Translocase of inner mitochondrial membrane 13; Belongs to the small Tim family. (95 aa)
ENSCSAP00000007626Uncharacterized protein; Belongs to the GroES chaperonin family. (102 aa)
TIMM8ATranslocase of inner mitochondrial membrane 8A; Belongs to the small Tim family. (97 aa)
CCT8Chaperonin containing TCP1 subunit 8. (548 aa)
PSMG1Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2. (288 aa)
CANXCalnexin. (610 aa)
LOC103219534SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (172 aa)
CALRCalreticulin. (417 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (166 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (558 aa)
CALR3Calreticulin. (367 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (442 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (556 aa)
ENSCSAP00000017870Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
ENSCSAP00000017740Uncharacterized protein; Belongs to the GroES chaperonin family. (97 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
TIMM8BTranslocase of inner mitochondrial membrane 8 homolog B; Belongs to the small Tim family. (98 aa)
CRYABCrystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
CLGNCalmegin. (610 aa)
ENSCSAP00000014307Uncharacterized protein. (510 aa)
PSMG2Proteasome assembly chaperone 2; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. Belongs to the PSMG2 family. (264 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5014 aa)
CCT6AUncharacterized protein. (453 aa)
GRPEL1GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (217 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (542 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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