STRINGSTRING
PRKCG PRKCG ADCY9 ADCY9 PPP3CB PPP3CB POMC POMC PPP1CA PPP1CA ADCY3 ADCY3 PTRHD1 PTRHD1 GRK2 GRK2 ADCY6 ADCY6 PDE1B PDE1B PDE4C PDE4C ADCY7 ADCY7 THAP6 THAP6 PRKAR1A PRKAR1A KPNA2 KPNA2 PRKCA PRKCA PPP3CA PPP3CA ENSCSAP00000000163 ENSCSAP00000000163 CREB1 CREB1 GNB3 GNB3 PDYN PDYN ITPR1 ITPR1 GNA15 GNA15 GNA11 GNA11 GNB5 GNB5 PRKAR2B PRKAR2B GNG7 GNG7 PPP2R5D PPP2R5D CAMK2A CAMK2A GNAI1 GNAI1 GNAT3 GNAT3 GNG13 GNG13 GNG10 GNG10 PDE1A PDE1A GNGT1 GNGT1 GNG11 GNG11 THAP7 THAP7 GNB4 GNB4 PRKCD PRKCD PLA2G4A PLA2G4A CAMKK1 CAMKK1 PLCB1 PLCB1 PLCB4 PLCB4 PPP2CA PPP2CA MAPK1 MAPK1 GNAI2 GNAI2 PDE1C PDE1C PPP3R1 PPP3R1 CAMK4 CAMK4 GNG2 GNG2 PRKAR2A PRKAR2A ENSCSAP00000011565 ENSCSAP00000011565 PRKX PRKX CAMK2B CAMK2B ADCY1 ADCY1 PPP2CB PPP2CB ADCY4 ADCY4 PDE4D PDE4D PPP3CC PPP3CC ADCY2 ADCY2 GNAL GNAL PRKAR1B PRKAR1B DCLK1 DCLK1 NBEA NBEA GNB2 GNB2 LRBA LRBA GNG8 GNG8 PPP2R1B PPP2R1B PPP1R1B PPP1R1B GNGT2 GNGT2 CAMKK2 CAMKK2 PPP2R1A PPP2R1A ITPR3 ITPR3 AHCYL1 AHCYL1 GNAI3 GNAI3 PRKACB PRKACB GNG12 GNG12 PDE4B PDE4B GNB1 GNB1 ENSCSAP00000017690 ENSCSAP00000017690 PRKACG PRKACG ENSCSAP00000018787 ENSCSAP00000018787 ADCY8 ADCY8 CNBD2 CNBD2 GNG4 GNG4 GNA14 GNA14 GNAQ GNAQ ITPR2 ITPR2 ADCY5 ADCY5 PLCB2 PLCB2 PDE4A PDE4A PLCB3 PLCB3 CDK5 CDK5 GNG3 GNG3 PRKACA PRKACA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
POMCProopiomelanocortin. (265 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PDE1BPhosphodiesterase. (536 aa)
PDE4CPhosphodiesterase. (607 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
THAP6THAP domain containing 6. (222 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (529 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
ENSCSAP00000000163Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GNB3G protein subunit beta 3. (340 aa)
PDYNProdynorphin. (253 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
GNA15G protein subunit alpha 15. (374 aa)
GNA11G protein subunit alpha 11. (394 aa)
GNB5G protein subunit beta 5. (353 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
GNAI1G protein subunit alpha i1. (354 aa)
GNAT3G protein subunit alpha transducin 3. (355 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PDE1APhosphodiesterase. (502 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
THAP7THAP domain containing 7. (309 aa)
GNB4G protein subunit beta 4. (340 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PLA2G4APhospholipase A2. (749 aa)
CAMKK1Calcium/calmodulin dependent protein kinase kinase 1. (505 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PDE1CPhosphodiesterase. (520 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (614 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
ENSCSAP00000011565Uncharacterized protein. (57 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (307 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
PDE4DPhosphodiesterase. (641 aa)
PPP3CCProtein phosphatase 3 catalytic subunit gamma. (509 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
GNALG protein subunit alpha L. (381 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
DCLK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (487 aa)
NBEAUncharacterized protein. (752 aa)
GNB2G protein subunit beta 2. (340 aa)
LRBALPS responsive beige-like anchor protein. (2113 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (599 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (590 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PDE4BPhosphodiesterase. (517 aa)
GNB1G protein subunit beta 1. (340 aa)
ENSCSAP00000017690Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
ENSCSAP00000018787Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (585 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQG protein subunit alpha q. (301 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
PDE4APhosphodiesterase 4A; Belongs to the cyclic nucleotide phosphodiesterase family. (891 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (354 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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