STRINGSTRING
POLR2I POLR2I ENSCSAP00000017424 ENSCSAP00000017424 ELOA ELOA GTF2H3 GTF2H3 ERCC2 ERCC2 CTDP1 CTDP1 POLR2J POLR2J GTF2F2 GTF2F2 POLR2D POLR2D IWS1 IWS1 ERCC3 ERCC3 NELFB NELFB SUPT16H SUPT16H CCNT2 CCNT2 CDK7 CDK7 GTF2H2 GTF2H2 NELFA NELFA NELFCD NELFCD WDR61 WDR61 CCNH CCNH TCEA1 TCEA1 MNAT1 MNAT1 CDK9 CDK9 POLR2H POLR2H AFF4 AFF4 ELOC ELOC CDC73 CDC73 GTF2H5 GTF2H5 POLR2E POLR2E POLR2K POLR2K POLR2A POLR2A LEO1 LEO1 NCBP1 NCBP1 POLR2L POLR2L CCNK CCNK ELOB ELOB EAF1 EAF1 MLLT1 MLLT1 GTF2F1 GTF2F1 MLLT3 MLLT3 NELFE NELFE NCBP2 NCBP2 GTF2H4 GTF2H4 RTF1 RTF1 EAF2 EAF2 SUPT6H SUPT6H POLR2F POLR2F POLR2G POLR2G CCNT1 CCNT1 SSRP1 SSRP1 SUPT4H1 SUPT4H1 ELL ELL POLR2B POLR2B GTF2H1 GTF2H1 POLR2C POLR2C CTR9 CTR9 AFF1 AFF1 NCBP2L NCBP2L PAF1 PAF1 SUPT5H SUPT5H ENSCSAP00000018734 ENSCSAP00000018734
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
ENSCSAP00000017424Ubiquitin-like domain-containing protein. (118 aa)
ELOAElongin A. (800 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (864 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
IWS1Interacts with SUPT6H, CTD assembly factor 1. (818 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
NELFBNegative elongation factor complex member B. (580 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (663 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
NELFANegative elongation factor complex member A. (539 aa)
NELFCDNegative elongation factor complex member C/D. (581 aa)
WDR61WD repeat domain 61. (305 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
TCEA1Transcription elongation factor A1. (301 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (488 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
AFF4AF4/FMR2 family member 4. (1163 aa)
ELOCElongin C; Belongs to the SKP1 family. (112 aa)
CDC73Cell division cycle 73. (531 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1971 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
CCNKCyclin K; Belongs to the cyclin family. (407 aa)
ELOBUbiquitin-like domain-containing protein. (118 aa)
EAF1ELL associated factor 1. (357 aa)
MLLT1MLLT1 super elongation complex subunit. (555 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (438 aa)
MLLT3MLLT3 super elongation complex subunit. (543 aa)
NELFENegative elongation factor complex member E. (380 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (235 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (670 aa)
EAF2ELL associated factor 2. (261 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1580 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (709 aa)
SUPT4H1Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (117 aa)
ELLElongation factor for RNA polymerase II. (621 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
AFF1AF4/FMR2 family member 1. (1214 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
SUPT5HTranscription elongation factor SPT5. (1087 aa)
ENSCSAP00000018734Ubiquitin-like domain-containing protein. (118 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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