STRINGSTRING
FYN FYN FER FER MMP9 MMP9 LYN LYN GAB4 GAB4 SRC SRC PIK3CA PIK3CA FNDC3B FNDC3B SOS1 SOS1 STAT1 STAT1 HRAS HRAS PTPN6 PTPN6 VAV1 VAV1 JAK2 JAK2 GRAP GRAP KRAS KRAS GRAP2 GRAP2 PIK3R2 PIK3R2 KIT KIT GRB2 GRB2 PRKCA PRKCA GAB2 GAB2 KITLG KITLG CBL CBL SOCS6 SOCS6 ERAS ERAS PTPN11 PTPN11 CHEK1 CHEK1 CSDE1 CSDE1 NRAS NRAS PIK3R3 PIK3R3 LCK LCK PTPRU PTPRU SOCS1 SOCS1 SH2B3 SH2B3 GRB7 GRB7 ELSPBP1 ELSPBP1 STAT5B STAT5B STAT5A STAT5A STAT3 STAT3 FNDC3A FNDC3A YES1 YES1 TEC TEC FES FES GRB10 GRB10 PIK3R1 PIK3R1 CMA1 CMA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FYNTyrosine-protein kinase. (537 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
LYNTyrosine-protein kinase. (512 aa)
GAB4GRB2 associated binding protein family member 4. (638 aa)
SRCTyrosine-protein kinase. (633 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
VAV1Vav guanine nucleotide exchange factor 1. (719 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
GRAPGRB2 related adaptor protein. (217 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GRAP2GRB2 related adaptor protein 2. (330 aa)
PIK3R2Uncharacterized protein. (629 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
GAB2GRB2 associated binding protein 2. (638 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
CBLCbl proto-oncogene. (907 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
ERASES cell expressed Ras. (233 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
CHEK1Checkpoint kinase 1. (749 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
LCKTyrosine-protein kinase. (513 aa)
PTPRUProtein tyrosine phosphatase receptor type U. (1446 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
SH2B3SH2B adaptor protein 3. (570 aa)
GRB7Growth factor receptor bound protein 7. (532 aa)
ELSPBP1Epididymal sperm binding protein 1. (245 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
STAT5ASignal transducer and activator of transcription. (798 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
YES1Tyrosine-protein kinase. (543 aa)
TECTyrosine-protein kinase. (630 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
GRB10Growth factor receptor bound protein 10. (593 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CMA1Chymase 1; Belongs to the peptidase S1 family. (247 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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