149 items (Chlorocebus sabaeus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Your Input:
	MEF2D	Myocyte enhancer factor 2D. (521 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
	NAB1	NGFI-A binding protein 1. (488 aa)
	RPS6KA2	Ribosomal protein S6 kinase. (730 aa)
	ENSCSAP00000008334	Uncharacterized protein. (72 aa)
	FOS	Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (681 aa)
	TCF12	Transcription factor 12. (682 aa)
	DNM3	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (869 aa)
	SRF	Serum response factor. (508 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (776 aa)
	FRS3	Fibroblast growth factor receptor substrate 3. (492 aa)
	PIK3CB	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	NTF3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
	PPP4R4	Protein phosphatase 4 regulatory subunit 4. (872 aa)
	MAP2K2	Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	CLTA	Clathrin light chain A. (218 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
	SHC4	SHC adaptor protein 4. (630 aa)
	AP2A2	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
	CHD4	Uncharacterized protein. (1914 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	TRIB1	Tribbles pseudokinase 1. (372 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1941 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1466 aa)
	ENSCSAP00000005580	ETS domain-containing protein. (412 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (317 aa)
	MAPK15	Mitogen-activated protein kinase. (593 aa)
	GRIN2B	Glutamate ionotropic receptor NMDA type subunit 2B. (1402 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1023 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (482 aa)
	FOSL1	FOS like 1, AP-1 transcription factor subunit. (271 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1754 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	ID4	Inhibitor of DNA binding 4, HLH protein. (161 aa)
	NTRK2	Neurotrophic receptor tyrosine kinase 2. (477 aa)
	EGR2	Early growth response 2. (476 aa)
	SHC3	SHC adaptor protein 3. (598 aa)
	ENSCSAP00000003372	Uncharacterized protein. (478 aa)
	KIDINS220	Kinase D interacting substrate 220. (1771 aa)
	ID2	Inhibitor of DNA binding 2. (134 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
	CDK5	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
	LYL1	LYL1 basic helix-loop-helix family member. (280 aa)
	DNAL4	Dynein light chain. (105 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	AP2B1	AP complex subunit beta. (951 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	ATF1	Activating transcription factor 1. (270 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1495 aa)
	EP300	E1A binding protein p300. (2416 aa)
	FNBP4	Formin binding protein 4. (1015 aa)
	PIK3R2	Uncharacterized protein. (629 aa)
	REST	RE1 silencing transcription factor. (1096 aa)
	NAB2	NGFI-A binding protein 2. (442 aa)
	TPH1	Tryptophan hydroxylase 1. (343 aa)
	MAPK12	Mitogen-activated protein kinase. (367 aa)
	MAPK11	Mitogen-activated protein kinase. (364 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	RRAD	GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SHC2	Uncharacterized protein. (590 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	MAP2K5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
	AP2M1	Adaptor related protein complex 2 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (251 aa)
	ELK1	Uncharacterized protein. (296 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
	SRC	Tyrosine-protein kinase. (633 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
	PLCG1	Phosphoinositide phospholipase C. (974 aa)
	CRK	CRK proto-oncogene, adaptor protein. (204 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (775 aa)
	DOCK3	Dedicator of cytokinesis 3; Belongs to the DOCK family. (2065 aa)
	ENSCSAP00000010255	Protein kinase domain-containing protein. (310 aa)
	MAPKAPK3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (246 aa)
	ATF2	Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
	RPS6KA3	Ribosomal protein S6 kinase. (740 aa)
	MEF2C	Myocyte enhancer factor 2C. (446 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (496 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1. (1264 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	ENSCSAP00000011134	Uncharacterized protein. (910 aa)
	RHOA	Ras homolog family member A. (193 aa)
	RALA	RAS like proto-oncogene A. (206 aa)
	EGR4	Early growth response 4. (588 aa)
	LOC103243620	WRNPLPNID domain-containing protein. (925 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	DUSP4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	EGR3	Early growth response 3. (387 aa)
	NELFB	Negative elongation factor complex member B. (580 aa)
	RALB	RAS like proto-oncogene B. (206 aa)
	SGK1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (839 aa)
	MEF2A	Myocyte enhancer factor 2A. (503 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
	NTRK3	Tyrosine-protein kinase receptor. (850 aa)
	SH3GL3	SH3 domain containing GRB2 like 3, endophilin A3. (347 aa)
	IRS2	Insulin receptor substrate 2. (906 aa)
	PPP4R1	Protein phosphatase 4 regulatory subunit 1. (933 aa)
	ENSCSAP00000013641	GLUCAGON domain-containing protein. (322 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1198 aa)
	RIT2	Ras like without CAAX 2. (149 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
	GAB1	GRB2 associated binding protein 1. (751 aa)
	STAT3	Signal transducer and activator of transcription. (770 aa)
	ENSCSAP00000014866	Uncharacterized protein. (177 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (599 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	ENSCSAP00000015592	Adaptin_N domain-containing protein. (132 aa)
	AP2A1	Alpha_adaptinC2 domain-containing protein. (817 aa)
	VRK3	VRK serine/threonine kinase 3. (482 aa)
	NTRK1	Tyrosine-protein kinase receptor. (796 aa)
	ID1	Inhibitor of DNA binding 1, HLH protein. (154 aa)
	RIT1	Ras like without CAAX 1. (233 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	SHC1	SHC adaptor protein 1. (474 aa)
	CSDE1	Cold shock domain containing E1. (844 aa)
	NRAS	NRAS proto-oncogene, GTPase. (189 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	F3	Coagulation factor III, tissue factor. (245 aa)
	RPS6KA1	Ribosomal protein S6 kinase. (735 aa)
	ID3	Inhibitor of DNA binding 3, HLH protein. (119 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (241 aa)
	JUND	JunD proto-oncogene, AP-1 transcription factor subunit. (348 aa)
	ARC	Activity regulated cytoskeleton associated protein. (396 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (367 aa)
	JUNB	JunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (239 aa)
	ASCL2	Achaete-scute family bHLH transcription factor 2. (193 aa)
	BDNF	Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
	VGF	VGF nerve growth factor inducible. (615 aa)
	ERAS	ES cell expressed Ras. (233 aa)
	NKPD1	NTPase KAP family P-loop domain containing 1. (608 aa)
	NTF4	Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1204 aa)

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1R1	ENSCSAP00000013641	ENSCSAP00000010897	ENSCSAP00000013641	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	GLUCAGON domain-containing protein.	0.980
ADCYAP1R1	NTRK2	ENSCSAP00000010897	ENSCSAP00000003745	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Neurotrophic receptor tyrosine kinase 2.	0.594
ADCYAP1R1	RPS6KA1	ENSCSAP00000010897	ENSCSAP00000017031	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Ribosomal protein S6 kinase.	0.408
ADORA2A	NTRK1	ENSCSAP00000006824	ENSCSAP00000015828	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Tyrosine-protein kinase receptor.	0.440
ADORA2A	NTRK2	ENSCSAP00000006824	ENSCSAP00000003745	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Neurotrophic receptor tyrosine kinase 2.	0.602
AP2A1	AP2A2	ENSCSAP00000015596	ENSCSAP00000006728	Alpha_adaptinC2 domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.937
AP2A1	AP2B1	ENSCSAP00000015596	ENSCSAP00000002554	Alpha_adaptinC2 domain-containing protein.	AP complex subunit beta.	0.984
AP2A1	AP2M1	ENSCSAP00000015596	ENSCSAP00000009723	Alpha_adaptinC2 domain-containing protein.	Adaptor related protein complex 2 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	0.996
AP2A1	CLTA	ENSCSAP00000015596	ENSCSAP00000006912	Alpha_adaptinC2 domain-containing protein.	Clathrin light chain A.	0.817
AP2A1	CLTC	ENSCSAP00000015596	ENSCSAP00000002174	Alpha_adaptinC2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.973
AP2A1	DNM1	ENSCSAP00000015596	ENSCSAP00000010205	Alpha_adaptinC2 domain-containing protein.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.549
AP2A1	DNM2	ENSCSAP00000015596	ENSCSAP00000003241	Alpha_adaptinC2 domain-containing protein.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.569
AP2A1	DNM3	ENSCSAP00000015596	ENSCSAP00000007857	Alpha_adaptinC2 domain-containing protein.	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.545
AP2A1	ENSCSAP00000015592	ENSCSAP00000015596	ENSCSAP00000015592	Alpha_adaptinC2 domain-containing protein.	Adaptin_N domain-containing protein.	0.925
AP2A1	GRB2	ENSCSAP00000015596	ENSCSAP00000001067	Alpha_adaptinC2 domain-containing protein.	Growth factor receptor bound protein 2.	0.541
AP2A1	SH3GL2	ENSCSAP00000015596	ENSCSAP00000005564	Alpha_adaptinC2 domain-containing protein.	SH3 domain containing GRB2 like 2, endophilin A1.	0.502
AP2A1	SH3GL3	ENSCSAP00000015596	ENSCSAP00000013339	Alpha_adaptinC2 domain-containing protein.	SH3 domain containing GRB2 like 3, endophilin A3.	0.502
AP2A1	VGF	ENSCSAP00000015596	ENSCSAP00000018989	Alpha_adaptinC2 domain-containing protein.	VGF nerve growth factor inducible.	0.508
AP2A2	AP2A1	ENSCSAP00000006728	ENSCSAP00000015596	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Alpha_adaptinC2 domain-containing protein.	0.937
AP2A2	AP2B1	ENSCSAP00000006728	ENSCSAP00000002554	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit beta.	0.997

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