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| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa) |
| | S100B | Protein S100; Belongs to the S-100 family. (92 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (686 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | ECSIT | ECSIT signalling integrator. (399 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | ATF1 | Activating transcription factor 1. (270 aa) |
| | FNBP4 | Formin binding protein 4. (1015 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (899 aa) |
| | N4BP1 | NEDD4 binding protein 1. (810 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1036 aa) |
| | LOC103239243 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | LOC103239253 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | SAA4 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1865 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
| | ALPK1 | Alpha kinase 1. (1181 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | ENSCSAP00000000080 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa) |
| | TLR8 | Toll like receptor 8; Belongs to the Toll-like receptor family. (1040 aa) |
| | TLR7 | Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa) |
| | CCDC71L | Coiled-coil domain containing 71 like. (235 aa) |
| | ENSCSAP00000018444 | Ubiquitin-like domain-containing protein. (127 aa) |
| | TICAM1 | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (711 aa) |
| | ENSCSAP00000018133 | Uncharacterized protein. (215 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | ENSCSAP00000017765 | Ubiquitin-like domain-containing protein. (155 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | TIFA | TRAF interacting protein with forkhead associated domain. (185 aa) |
| | ENSCSAP00000017575 | Ubiquitin-like domain-containing protein. (156 aa) |
| | TICAM2 | Toll like receptor adaptor molecule 2. (235 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (735 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1045 aa) |
| | ENSCSAP00000016317 | Uncharacterized protein. (992 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (91 aa) |
| | UBC | Uncharacterized protein. (228 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (670 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | VRK3 | VRK serine/threonine kinase 3. (482 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (599 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (933 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | MEF2A | Myocyte enhancer factor 2A. (503 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1345 aa) |
| | TRAF2 | TNF receptor-associated factor. (449 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa) |
| | KHNYN | KH and NYN domain containing. (678 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (429 aa) |
| | LOC103243620 | WRNPLPNID domain-containing protein. (925 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | ENSCSAP00000011477 | Uncharacterized protein. (207 aa) |
| | TMEM189-UBE2V1 | TMEM189-UBE2V1 readthrough. (370 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | MEF2C | Myocyte enhancer factor 2C. (446 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | ENSCSAP00000010823 | Protein kinase domain-containing protein. (169 aa) |
| | MAP3K20 | Protein kinase domain-containing protein. (292 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (740 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | MAPKAPK3 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSCSAP00000010255 | Protein kinase domain-containing protein. (310 aa) |
| | DUSP7 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa) |
| | LOC103227720 | TIR domain-containing protein. (1032 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | ELK1 | Uncharacterized protein. (296 aa) |
| | LY96 | Lymphocyte antigen 96. (160 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (443 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (393 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (375 aa) |
| | ENSCSAP00000008892 | Uncharacterized protein. (190 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (403 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (730 aa) |
| | ENSCSAP00000008334 | Uncharacterized protein. (72 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (489 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa) |
| | RPS6KA5 | Ribosomal protein S6 kinase. (776 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | NLRP6 | NLR family pyrin domain containing 6. (894 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (872 aa) |
| | IRF7 | Interferon regulatory factor 7. (506 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (326 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (626 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (510 aa) |
| | ENSCSAP00000005580 | ETS domain-containing protein. (412 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | MAPK15 | Mitogen-activated protein kinase. (593 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1377 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (398 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (445 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (517 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
