STRINGSTRING
RCBTB1 RCBTB1 PRIM2 PRIM2 PRIM1 PRIM1 TEN1 TEN1 TERF2 TERF2 CHTF8 CHTF8 POLD3 POLD3 ACD ACD TERF2IP TERF2IP POLD1 POLD1 RFC5 RFC5 RFC2 RFC2 RFC3 RFC3 STN1 STN1 ENSCSAP00000003124 ENSCSAP00000003124 POLA2 POLA2 POLD4 POLD4 ENSCSAP00000005289 ENSCSAP00000005289 RFC4 RFC4 POT1 POT1 CTC1 CTC1 DSCC1 DSCC1 CHTF18 CHTF18 PCNA PCNA RCBTB2 RCBTB2 RFC1 RFC1 TINF2 TINF2 POLD2 POLD2 POLA1 POLA1 TERF1 TERF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa)
TEN1Uncharacterized protein. (94 aa)
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (500 aa)
CHTF8Chromosome transmission fidelity factor 8. (121 aa)
POLD3Uncharacterized protein. (466 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (537 aa)
TERF2IPTERF2 interacting protein. (400 aa)
POLD1DNA polymerase. (1086 aa)
RFC5Replication factor C subunit 5. (340 aa)
RFC2Replication factor C subunit 2. (353 aa)
RFC3Replication factor C subunit 3. (356 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)
ENSCSAP00000003124BTB domain-containing protein. (463 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
POLD4Uncharacterized protein. (107 aa)
ENSCSAP00000005289DNA primase; Belongs to the eukaryotic-type primase small subunit family. (398 aa)
RFC4Replication factor C subunit 4. (363 aa)
POT1Protection of telomeres 1. (634 aa)
CTC1CST telomere replication complex component 1. (1209 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (399 aa)
CHTF18Chromosome transmission fidelity factor 18. (976 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
RFC1Replication factor C subunit 1. (985 aa)
TINF2TERF1 interacting nuclear factor 2. (424 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
POLA1DNA polymerase. (1465 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (440 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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