STRINGSTRING
FLRT2 FLRT2 FGF2 FGF2 ESRP2 ESRP2 FRS2 FRS2 POLR2I POLR2I FGF5 FGF5 FGFR2 FGFR2 TIAL1 TIAL1 GRB2 GRB2 ENSCSAP00000001097 ENSCSAP00000001097 POLR2C POLR2C POLR2B POLR2B UBA52 UBA52 HNRNPA1 HNRNPA1 FGF8 FGF8 MAPK3 MAPK3 POLR2G POLR2G POLR2F POLR2F SPRED1 SPRED1 KRAS KRAS HNRNPM HNRNPM RBFOX2 RBFOX2 BRAF BRAF NCBP2 NCBP2 FGFR4 FGFR4 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 GTF2F1 GTF2F1 FGF18 FGF18 ENSCSAP00000006444 ENSCSAP00000006444 POLR2L POLR2L FGF7 FGF7 FGF16 FGF16 NCBP1 NCBP1 HRAS HRAS FGF6 FGF6 FGF23 FGF23 FRS3 FRS3 POLR2A POLR2A MKNK2 MKNK2 POLR2K POLR2K PTBP3 PTBP3 POLR2E POLR2E SOS1 SOS1 FGF1 FGF1 ESRP1 ESRP1 PTBP1 PTBP1 FNDC3B FNDC3B FGF22 FGF22 PIK3CA PIK3CA PPP2CA PPP2CA MAPK1 MAPK1 SRC SRC POLR2H POLR2H PLCG1 PLCG1 RPS27A RPS27A SPRED2 SPRED2 TIA1 TIA1 ANOS1 ANOS1 FGFR1 FGFR1 ENSCSAP00000019219 ENSCSAP00000019219 GALNT3 GALNT3 FGFRL1 FGFRL1 FGFR3 FGFR3 PPP2CB PPP2CB PIK3R1 PIK3R1 FGF17 FGF17 FGFBP1 FGFBP1 FGF10 FGF10 FGF20 FGF20 POLR2D POLR2D KLB KLB FNDC3A FNDC3A GTF2F2 GTF2F2 KL KL FGF9 FGF9 POLR2J POLR2J GAB1 GAB1 CBL CBL PTPN11 PTPN11 PPP2R1A PPP2R1A UBC UBC SHC1 SHC1 CSDE1 CSDE1 NRAS NRAS PTBP2 PTBP2 STIL STIL MKNK1 MKNK1 LOC103247992 LOC103247992 ENSCSAP00000017575 ENSCSAP00000017575 NCBP2L NCBP2L ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017844 ENSCSAP00000017844 FGFBP3 FGFBP3 LOC103214464 LOC103214464 SPRY2 SPRY2 FLRT3 FLRT3 ENSCSAP00000018390 ENSCSAP00000018390 ENSCSAP00000018444 ENSCSAP00000018444 FLRT1 FLRT1 ERAS ERAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FLRT2Fibronectin leucine rich transmembrane protein 2. (660 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
ESRP2Epithelial splicing regulatory protein 2. (715 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (375 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSCSAP00000001097Uncharacterized protein. (267 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (372 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (692 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (366 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (482 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (235 aa)
FGFR4Fibroblast growth factor receptor. (806 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (438 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
ENSCSAP00000006444Uncharacterized protein. (304 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1971 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
PTBP3Polypyrimidine tract binding protein 3. (524 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
ESRP1Epithelial splicing regulatory protein 1. (663 aa)
PTBP1Polypyrimidine tract binding protein 1. (556 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SRCTyrosine-protein kinase. (633 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
SPRED2Sprouty related EVH1 domain containing 2. (415 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
ANOS1Anosmin 1. (579 aa)
FGFR1Fibroblast growth factor receptor. (830 aa)
ENSCSAP00000019219Uncharacterized protein. (320 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (633 aa)
FGFRL1Fibroblast growth factor receptor like 1. (474 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (333 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
KLBKlotho beta. (907 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
KLKlotho. (1010 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
CBLCbl proto-oncogene. (907 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
UBCUncharacterized protein. (228 aa)
SHC1SHC adaptor protein 1. (474 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PTBP2Polypyrimidine tract binding protein 2. (531 aa)
STILSTIL centriolar assembly protein. (1287 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (418 aa)
LOC103247992Uncharacterized protein. (320 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017844Uncharacterized protein. (372 aa)
FGFBP3Fibroblast growth factor binding protein 3. (260 aa)
LOC103214464Uncharacterized protein. (319 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
ENSCSAP00000018390Uncharacterized protein. (320 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
FLRT1Fibronectin leucine rich transmembrane protein 1. (674 aa)
ERASES cell expressed Ras. (233 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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