STRINGSTRING
PRKCI PRKCI RAB6A RAB6A H3F3B H3F3B EHF EHF EP300 EP300 TNRC6B TNRC6B ST3GAL6 ST3GAL6 NOTCH3 NOTCH3 ATP2A1 ATP2A1 POGLUT1 POGLUT1 FURIN FURIN RBPJ RBPJ NOTCH1 NOTCH1 H2AZ2 H2AZ2 ELF3 ELF3 MAMLD1 MAMLD1 ENSCSAP00000009816 ENSCSAP00000009816 CRB1 CRB1 CREBBP CREBBP KAT2B KAT2B B4GALT1 B4GALT1 SIRT6 SIRT6 TP53 TP53 SEL1L SEL1L SNW1 SNW1 LOC103232061 LOC103232061 E2F1 E2F1 POFUT1 POFUT1 AGO3 AGO3 ST3GAL3 ST3GAL3 MOV10 MOV10 NOTCH2 NOTCH2 TMED2 TMED2 RFNG RFNG ST3GAL4 ST3GAL4 ATP2A2 ATP2A2 KAT2A KAT2A MAML2 MAML2 LFNG LFNG TFDP1 TFDP1 ATP2A3 ATP2A3 ENSCSAP00000019055 ENSCSAP00000019055 LOC103221619 LOC103221619 H2AJ H2AJ H2BC1 H2BC1 LOC103221946-2 LOC103221946-2 LOC103222003 LOC103222003 H2BC3 H2BC3 H2BC4 H2BC4 H2AC6 H2AC6 H2AC7 H2AC7 LOC103221946 LOC103221946 H2BC11 H2BC11 LOC103221972 LOC103221972 H2BC15 H2BC15 H3C11 H3C11 HIST1H2BO HIST1H2BO ENSCSAP00000017985 ENSCSAP00000017985 LOC103232262 LOC103232262 JUN JUN LOC103247786 LOC103247786 H2AC20 H2AC20 H2BU1 H2BU1 ENSCSAP00000017607 ENSCSAP00000017607 LOC103232850-2 LOC103232850-2 LOC103232850 LOC103232850 H2AX H2AX AGO4 AGO4 AGO1 AGO1 MFNG MFNG E2F3 E2F3 H2BC5 H2BC5 MAML1 MAML1 RUNX1 RUNX1 CCND1 CCND1 NOTCH4 NOTCH4 AGO2 AGO2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. (482 aa)
RAB6ARAB6A, member RAS oncogene family. (208 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
EHFETS homologous factor. (322 aa)
EP300E1A binding protein p300. (2416 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1773 aa)
ST3GAL6ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Belongs to the glycosyltransferase 29 family. (331 aa)
NOTCH3Notch receptor 3. (1980 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (994 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (357 aa)
NOTCH1Notch receptor 1. (2555 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
ELF3E74 like ETS transcription factor 3. (371 aa)
MAMLD1Mastermind like domain containing 1. (810 aa)
ENSCSAP00000009816Histone H3; Belongs to the histone H3 family. (136 aa)
CRB1Crumbs cell polarity complex component 1. (1335 aa)
CREBBPCREB binding protein. (2417 aa)
KAT2BLysine acetyltransferase 2B. (675 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
SIRT6Sirtuin 6. (355 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
SNW1SNW domain containing 1. (536 aa)
LOC103232061Histone domain-containing protein. (136 aa)
E2F1E2F transcription factor 1. (437 aa)
POFUT1Protein O-fucosyltransferase 1. (365 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
ST3GAL3ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Belongs to the glycosyltransferase 29 family. (281 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
NOTCH2Notch receptor 2. (2471 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (205 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (997 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
MAML2Mastermind like transcriptional coactivator 2. (923 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (236 aa)
TFDP1Transcription factor. (410 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1038 aa)
ENSCSAP00000019055Transcription factor. (409 aa)
LOC103221619Histone domain-containing protein. (136 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103221946-2Histone H3.1. (136 aa)
LOC103222003Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC4Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103221946Histone H3.1. (136 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103221972Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
H3C11Histone H3; Belongs to the histone H3 family. (136 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
ENSCSAP00000017985Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC103232262Histone H3; Belongs to the histone H3 family. (136 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
LOC103247786Histone H3; Belongs to the histone H3 family. (136 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSCSAP00000017607Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC103232850-2Histone H2A-Bbd type 2/3-like. (115 aa)
LOC103232850Histone H2A; Belongs to the histone H2A family. (115 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
E2F3E2F_CC-MB domain-containing protein. (224 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
MAML1Mastermind like transcriptional coactivator 1. (790 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (456 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
NOTCH4Notch receptor 4. (1994 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (904 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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