STRINGSTRING
ERBB2 ERBB2 CSDE1 CSDE1 NRAS NRAS ERAS ERAS EGF EGF BTC BTC EREG EREG GRB2 GRB2 KRAS KRAS ERBB4 ERBB4 ENSCSAP00000005731 ENSCSAP00000005731 NRG3 NRG3 SOS1 SOS1 HRAS HRAS HBEGF HBEGF NRG2 NRG2 NRG4 NRG4 NRG1 NRG1 EGFR EGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
ERASES cell expressed Ras. (233 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
BTCBetacellulin. (171 aa)
EREGEpiregulin. (171 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ERBB4Protein kinase domain-containing protein. (622 aa)
ENSCSAP00000005731Protein kinase domain-containing protein. (479 aa)
NRG3Uncharacterized protein. (376 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
NRG2Neuregulin 2. (850 aa)
NRG4Neuregulin 4. (117 aa)
NRG1Neuregulin 1. (467 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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