STRINGSTRING
MAML2 MAML2 NCSTN NCSTN NOTCH2 NOTCH2 HES5 HES5 MIB2 MIB2 HES4 HES4 ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 NEURL1B NEURL1B PSENEN PSENEN NEURL1 NEURL1 MDK MDK EP300 EP300 CNTN1 CNTN1 MAMLD1 MAMLD1 DLL4 DLL4 FCER2 FCER2 MAML1 MAML1 HES1 HES1 ENSCSAP00000005586 ENSCSAP00000005586 JAG2 JAG2 CREB1 CREB1 DLL1 DLL1 ADAM10 ADAM10 APH1B APH1B PSEN1 PSEN1 JAG1 JAG1 RPS27A RPS27A GZMB GZMB PSEN2 PSEN2 RBPJ RBPJ MIB1 MIB1 APH1A APH1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAML2Mastermind like transcriptional coactivator 2. (923 aa)
NCSTNNicastrin. (709 aa)
NOTCH2Notch receptor 2. (2471 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (955 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (555 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
MDKUncharacterized protein. (159 aa)
EP300E1A binding protein p300. (2416 aa)
CNTN1Contactin 1. (1018 aa)
MAMLD1Mastermind like domain containing 1. (810 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
FCER2Fc fragment of IgE receptor II. (308 aa)
MAML1Mastermind like transcriptional coactivator 1. (790 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
ENSCSAP00000005586Uncharacterized protein. (163 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
PSEN1Presenilin 1. (467 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (290 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (357 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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