STRINGSTRING
SMAD6 SMAD6 CHRDL2 CHRDL2 SMURF2 SMURF2 BMPR1B BMPR1B AMHR2 AMHR2 ACVRL1 ACVRL1 FSTL1 FSTL1 UBE2D1 UBE2D1 CHRDL1 CHRDL1 CER1 CER1 BMPR1A BMPR1A GDF2 GDF2 BMPR2 BMPR2 AMH AMH SMAD5 SMAD5 BMP2 BMP2 ACVR2B ACVR2B BMP10 BMP10 ZFYVE16 ZFYVE16 ACVR1 ACVR1 ACVR2A ACVR2A SMURF1 SMURF1 SMAD9 SMAD9 SMAD7 SMAD7 SMAD4 SMAD4 SMAD1 SMAD1 SKI SKI NOG NOG GREM2 GREM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD6Mothers against decapentaplegic homolog. (496 aa)
CHRDL2Chordin like 2. (429 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (474 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
FSTL1Follistatin like 1. (308 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CHRDL1Chordin like 1. (458 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF2Growth differentiation factor 2. (429 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
AMHAnti-Mullerian hormone. (566 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1540 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
SKISKI proto-oncogene. (728 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GREM2Gremlin. (168 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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