STRINGSTRING
KRAS KRAS PIK3R2 PIK3R2 GRB2 GRB2 ANGPT1 ANGPT1 SOS1 SOS1 GRB14 GRB14 PIK3R1 PIK3R1 DOK2 DOK2 ANGPT2 ANGPT2 GRB7 GRB7 PTPN11 PTPN11 SHC1 SHC1 CSDE1 CSDE1 NRAS NRAS TIE1 TIE1 ANGPTL7 ANGPTL7 PIK3CA PIK3CA ERAS ERAS PIK3CB PIK3CB HRAS HRAS ANGPT4 ANGPT4 TEK TEK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRASKRAS proto-oncogene, GTPase. (189 aa)
PIK3R2Uncharacterized protein. (629 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ANGPT1Angiopoietin 1. (407 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
DOK2Docking protein 2. (412 aa)
ANGPT2Angiopoietin 2. (495 aa)
GRB7Growth factor receptor bound protein 7. (532 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
SHC1SHC adaptor protein 1. (474 aa)
CSDE1Cold shock domain containing E1. (844 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
ANGPTL7Angiopoietin like 7. (344 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ERASES cell expressed Ras. (233 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
ANGPT4Angiopoietin 4. (503 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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