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FMO4 FMO4 CYP2U1 CYP2U1 ADH7 ADH7 ADH1A ADH1A ADH6 ADH6 ADH4 ADH4 ADH5 ADH5 CYB5B CYB5B ENSCSAP00000000928 ENSCSAP00000000928 ENSCSAP00000000935 ENSCSAP00000000935 CYP27B1 CYP27B1 FDXR FDXR CYP2R1 CYP2R1 CES5A CES5A ENSCSAP00000001481 ENSCSAP00000001481 ENSCSAP00000001489 ENSCSAP00000001489 ENSCSAP00000001494 ENSCSAP00000001494 LOC103223410 LOC103223410 CYP2D6 CYP2D6 CYP4F11 CYP4F11 CYP4F12 CYP4F12 CYP4F57 CYP4F57 CYP4F3 CYP4F3 CYP4F8 CYP4F8 CYP4F23 CYP4F23 CYP4F22 CYP4F22 CYP2C8 CYP2C8 CYP2C9 CYP2C9 CYP26C1 CYP26C1 CYP26A1 CYP26A1 CYP2E1 CYP2E1 PAOX PAOX AOC1 AOC1 NQO2 NQO2 BPHL BPHL FDX1L FDX1L ALDH3A1 ALDH3A1 FOXRED2 FOXRED2 CYP1D1 CYP1D1 ALDH1A1 ALDH1A1 TBXAS1 TBXAS1 NCOA1 NCOA1 POMC POMC CYP27A1 CYP27A1 AIP AIP CCNDBP1 CCNDBP1 CYP21A2 CYP21A2 CYP11B2 CYP11B2 CYP11B1 CYP11B1 CYP20A1 CYP20A1 CYP46A1 CYP46A1 FAM78B FAM78B CYP19A1 CYP19A1 FMO3 FMO3 FMO2 FMO2 FMO1 FMO1 ACSS2 ACSS2 AADAC AADAC CYP1B1 CYP1B1 CBFA2T2 CBFA2T2 HSP90AB1 HSP90AB1 CYP51A1 CYP51A1 CYP39A1 CYP39A1 AIPL1 AIPL1 RUNX1T1 RUNX1T1 PTGS1 PTGS1 AHR AHR NCOA2 NCOA2 MAOB MAOB MAOA MAOA CYP11A1 CYP11A1 CYP1A1 CYP1A1 CYP7B1 CYP7B1 CYP7A1 CYP7A1 FAM78A FAM78A PTGIS PTGIS ARNT2 ARNT2 CYP26B1 CYP26B1 CYP24A1 CYP24A1 RXRA RXRA TTI2 TTI2 MARC2 MARC2 MTARC1 MTARC1 EPHX1 EPHX1 CYP27C1 CYP27C1 CMBL CMBL ENSCSAP00000013463 ENSCSAP00000013463 CYP2W1 CYP2W1 CYP3A5 CYP3A5 CYP3A7 CYP3A7 CYP3A4 CYP3A4 CYP3A7-2 CYP3A7-2 CYP3A43 CYP3A43 ARNT ARNT POR POR ACSS1 ACSS1 FMO5 FMO5 CYP2A24 CYP2A24 CYP2A23 CYP2A23 CYP2B6 CYP2B6 CYP2G2 CYP2G2 CYP2A28 CYP2A28 CYP2S1 CYP2S1 NR1H4 NR1H4 ENSCSAP00000014675 ENSCSAP00000014675 ENSCSAP00000014683 ENSCSAP00000014683 AOC3 AOC3 AOC2 AOC2 CYP4V2 CYP4V2 FDX1 FDX1 CBFA2T3 CBFA2T3 ALDH16A1 ALDH16A1 ENSCSAP00000015509 ENSCSAP00000015509 CYP2J2 CYP2J2 CYP4A22 CYP4A22 CYP4X1 CYP4X1 ENSCSAP00000016771 ENSCSAP00000016771 CYP4B1 CYP4B1 AADACL3 AADACL3 AADACL4 AADACL4 ALDH1B1 ALDH1B1 CCDC160 CCDC160 CYP8B1 CYP8B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (544 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (374 aa)
ADH1AAlcohol dehydrogenase 1A (class I), alpha polypeptide. (375 aa)
ADH6Alcohol dehydrogenase 6 (class V). (374 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (419 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (372 aa)
CYB5BCytochrome b5 type B; Belongs to the cytochrome b5 family. (150 aa)
ENSCSAP00000000928Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (560 aa)
ENSCSAP00000000935Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (645 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
FDXRNADPH:adrenodoxin oxidoreductase, mitochondrial. (491 aa)
CYP2R1Cytochrome P450 family 2 subfamily R member 1. (554 aa)
CES5ACarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (488 aa)
ENSCSAP00000001481Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (532 aa)
ENSCSAP00000001489Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (567 aa)
ENSCSAP00000001494Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
LOC103223410Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
CYP2D6Uncharacterized protein; Belongs to the cytochrome P450 family. (507 aa)
CYP4F11Cytochrome P450 family 4 subfamily F member 11; Belongs to the cytochrome P450 family. (520 aa)
CYP4F12Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP4F57Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP4F3Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (520 aa)
CYP4F23Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP4F22Cytochrome P450 family 4 subfamily F member 22. (531 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa)
CYP2C9Uncharacterized protein; Belongs to the cytochrome P450 family. (468 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (428 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (536 aa)
PAOXAmino_oxidase domain-containing protein. (449 aa)
AOC1Amine oxidase. (755 aa)
NQO2N-ribosyldihydronicotinamide:quinone reductase 2. (231 aa)
BPHLBiphenyl hydrolase like. (291 aa)
FDX1L2Fe-2S ferredoxin-type domain-containing protein. (183 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
FOXRED2FAD dependent oxidoreductase domain containing 2. (684 aa)
CYP1D1Uncharacterized protein. (363 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (534 aa)
NCOA1Nuclear receptor coactivator. (1399 aa)
POMCProopiomelanocortin. (265 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa)
AIPPeptidylprolyl isomerase. (330 aa)
CCNDBP1Cyclin D1 binding protein 1. (360 aa)
CYP21A2Cytochrome P450 family 21 subfamily A member 2; Belongs to the cytochrome P450 family. (495 aa)
CYP11B2Uncharacterized protein; Belongs to the cytochrome P450 family. (451 aa)
CYP11B1Cytochrome P450 family 11 subfamily B member 1; Belongs to the cytochrome P450 family. (416 aa)
CYP20A1Cytochrome P450 family 20 subfamily A member 1. (462 aa)
CYP46A1Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa)
FAM78BFamily with sequence similarity 78 member B. (261 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
FMO3Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (702 aa)
AADACArylacetamide deacetylase. (399 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (595 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (509 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
AIPL1Aryl hydrocarbon receptor interacting protein like 1. (372 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (577 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
AHRUncharacterized protein. (850 aa)
NCOA2Nuclear receptor coactivator. (1464 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (527 aa)
CYP11A1Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (464 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (436 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa)
FAM78AFamily with sequence similarity 78 member A. (283 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (492 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (717 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
RXRARetinoid X receptor alpha. (462 aa)
TTI2TELO2 interacting protein 2. (475 aa)
MARC2Mitochondrial amidoxime reducing component 2. (335 aa)
MTARC1MOSC domain-containing protein. (337 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (455 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
CMBLCarboxymethylenebutenolidase homolog. (245 aa)
ENSCSAP00000013463Uncharacterized protein. (701 aa)
CYP2W1Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (490 aa)
CYP3A5Cytochrome P450 family 3 subfamily A member 5. (503 aa)
CYP3A7Uncharacterized protein. (532 aa)
CYP3A4Cytochrome P450 family 3 subfamily A member 4; Belongs to the cytochrome P450 family. (359 aa)
CYP3A7-2Uncharacterized protein. (564 aa)
CYP3A43Cytochrome P450 family 3 subfamily A member 43. (503 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
ACSS1Acyl-CoA synthetase short chain family member 1. (399 aa)
FMO5Dimethylaniline monooxygenase [N-oxide-forming]. (533 aa)
CYP2A24Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
CYP2A23Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa)
CYP2G2Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
CYP2A28Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1. (512 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (476 aa)
ENSCSAP00000014675CS domain-containing protein. (165 aa)
ENSCSAP00000014683Amine oxidase. (749 aa)
AOC3Amine oxidase. (763 aa)
AOC2Amine oxidase. (756 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
FDX1Ferredoxin 1. (184 aa)
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (591 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (802 aa)
ENSCSAP00000015509Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (517 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
CYP4A22Uncharacterized protein. (455 aa)
CYP4X1Cytochrome P450 family 4 subfamily X member 1; Belongs to the cytochrome P450 family. (509 aa)
ENSCSAP00000016771Uncharacterized protein. (433 aa)
CYP4B1Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
AADACL3Arylacetamide deacetylase like 3. (350 aa)
AADACL4Uncharacterized protein. (407 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
CCDC160Coiled-coil domain containing 160. (325 aa)
CYP8B1Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (501 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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