STRINGSTRING
TWISTNB TWISTNB SUV39H1 SUV39H1 PHF19 PHF19 MYBBP1A MYBBP1A GTF2H5 GTF2H5 MTA3 MTA3 DNMT3B DNMT3B POLR2E POLR2E POLR2K POLR2K LOC103232061 LOC103232061 MYO1B MYO1B MBD3 MBD3 POLR1C POLR1C TBP TBP SF3B1 SF3B1 CHD3 CHD3 SAP30L SAP30L POLR1E POLR1E POLR2L POLR2L CHD4 CHD4 ERCC6 ERCC6 UHRF1 UHRF1 ARID4B ARID4B KAT2B KAT2B PHF1 PHF1 H2BW2 H2BW2 MTA1 MTA1 ENSCSAP00000005636 ENSCSAP00000005636 ENSCSAP00000005631 ENSCSAP00000005631 EHMT2 EHMT2 ENSCSAP00000004987 ENSCSAP00000004987 ENSCSAP00000004852 ENSCSAP00000004852 DNMT3A DNMT3A SMARCA1 SMARCA1 GTF2H4 GTF2H4 ZNRD1 ZNRD1 AEBP2 AEBP2 H2BC5 H2BC5 DNMT3L DNMT3L ENSCSAP00000003991 ENSCSAP00000003991 DDX50 DDX50 DEK DEK TET1 TET1 JARID2 JARID2 SIRT1 SIRT1 DNMT1 DNMT1 TAF1B TAF1B GSK3B GSK3B EZH2 EZH2 POLR2F POLR2F SUZ12 SUZ12 EED EED TET2 TET2 RRP8 RRP8 SAP30BP SAP30BP H3F3B H3F3B MNAT1 MNAT1 LOC103221619 LOC103221619 H2AJ H2AJ LOC103221971 LOC103221971 H2BC1 H2BC1 LOC103221946-2 LOC103221946-2 LOC103222003 LOC103222003 H2BC3 H2BC3 H2BC4 H2BC4 H2AC6 H2AC6 H2AC7 H2AC7 LOC103221946 LOC103221946 H2BC11 H2BC11 LOC103221972 LOC103221972 H2BC13 H2BC13 H2BC14 H2BC14 H2BC15 H2BC15 H3C11 H3C11 HIST1H2BO HIST1H2BO MBD3L1 MBD3L1 ENSCSAP00000017985 ENSCSAP00000017985 LOC103232262 LOC103232262 LOC103247786 LOC103247786 H2AC20 H2AC20 H2BC21 H2BC21 ENSCSAP00000017750 ENSCSAP00000017750 H2BU1 H2BU1 LOC103229948 LOC103229948 ENSCSAP00000017607 ENSCSAP00000017607 LOC103240948 LOC103240948 LOC103232850-2 LOC103232850-2 LOC103232850 LOC103232850 H2AX H2AX HDAC1 HDAC1 MTF2 MTF2 GATAD2B GATAD2B ENSCSAP00000016053 ENSCSAP00000016053 GTF2H3 GTF2H3 SUDS3 SUDS3 MYO1H MYO1H TDG TDG KAT2A KAT2A SAP30 SAP30 CD3EAP CD3EAP ERCC2 ERCC2 TAF1C TAF1C EZH1 EZH1 TAF1D TAF1D SMARCA5 SMARCA5 UBTF UBTF BAZ1B BAZ1B SAP18 SAP18 MBD2 MBD2 SAP130 SAP130 ERCC3 ERCC3 POLR1B POLR1B POLR1A POLR1A TAF1A TAF1A BAZ2B BAZ2B CDK7 CDK7 GTF2H2 GTF2H2 MYO1G MYO1G H2AZ2 H2AZ2 HDAC2 HDAC2 TET3 TET3 TTF1 TTF1 RBBP7 RBBP7 CCNH CCNH SIN3A SIN3A MYO1C MYO1C POLR2H POLR2H ENSCSAP00000009816 ENSCSAP00000009816 MYO1A MYO1A GTF2H1 GTF2H1 BAZ2A BAZ2A GATAD2A GATAD2A SIN3B SIN3B EP300 EP300 MYO1D MYO1D MTA2 MTA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TWISTNBTWIST neighbor. (338 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa)
PHF19PHD finger protein 19. (580 aa)
MYBBP1AMYB binding protein 1a. (1328 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
LOC103232061Histone domain-containing protein. (136 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1136 aa)
MBD3Methyl-CpG binding domain protein 3. (291 aa)
POLR1CRNA polymerase I and III subunit C. (346 aa)
TBPTATA-box binding protein. (270 aa)
SF3B1Splicing factor 3b subunit 1. (1304 aa)
CHD3Chromodomain helicase DNA binding protein 3. (1965 aa)
SAP30LSAP30 like. (184 aa)
POLR1ERNA polymerase I subunit E. (419 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
CHD4Uncharacterized protein. (1914 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1494 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (801 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
KAT2BLysine acetyltransferase 2B. (675 aa)
PHF1PHD finger protein 1. (567 aa)
H2BW2H2B histone family member M; Belongs to the histone H2B family. (175 aa)
MTA1Metastasis associated 1. (714 aa)
ENSCSAP00000005636Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
ENSCSAP00000005631Histone domain-containing protein; Belongs to the histone H2B family. (175 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1197 aa)
ENSCSAP00000004987SAP domain-containing protein. (361 aa)
ENSCSAP00000004852Uncharacterized protein. (195 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (723 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1058 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ZNRD1DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
AEBP2AE binding protein 2. (516 aa)
H2BC5Histone H2B; Belongs to the histone H2B family. (126 aa)
DNMT3LPHD-type domain-containing protein. (387 aa)
ENSCSAP00000003991Uncharacterized protein. (851 aa)
DDX50DExD-box helicase 50. (737 aa)
DEKUncharacterized protein. (129 aa)
TET1Tet methylcytosine dioxygenase 1. (2132 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
SIRT1Sirtuin 1. (743 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa)
TAF1BTATA-box binding protein associated factor, RNA polymerase I subunit B. (588 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
EEDEmbryonic ectoderm development. (441 aa)
TET2Tet methylcytosine dioxygenase 2. (2002 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (456 aa)
SAP30BPSAP30 binding protein. (308 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
LOC103221619Histone domain-containing protein. (136 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
LOC103221971Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103221946-2Histone H3.1. (136 aa)
LOC103222003Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC4Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC7Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103221946Histone H3.1. (136 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103221972Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC13Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC14Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
H3C11Histone H3; Belongs to the histone H3 family. (136 aa)
HIST1H2BOHistone H2B; Belongs to the histone H2B family. (126 aa)
MBD3L1Methyl-CpG binding domain protein 3 like 1. (194 aa)
ENSCSAP00000017985Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC103232262Histone H3; Belongs to the histone H3 family. (136 aa)
LOC103247786Histone H3; Belongs to the histone H3 family. (136 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSCSAP00000017750Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103229948Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSCSAP00000017607Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC103240948Uncharacterized protein. (375 aa)
LOC103232850-2Histone H2A-Bbd type 2/3-like. (115 aa)
LOC103232850Histone H2A; Belongs to the histone H2A family. (115 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
MTF2Metal response element binding transcription factor 2. (593 aa)
GATAD2BGATA zinc finger domain containing 2B. (593 aa)
ENSCSAP00000016053Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
SUDS3SDS3 homolog, SIN3A corepressor complex component. (328 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (963 aa)
TDGThymine DNA glycosylase. (267 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
SAP30Sin3A associated protein 30. (220 aa)
CD3EAPCD3e molecule associated protein. (513 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa)
TAF1CTATA-box binding protein associated factor, RNA polymerase I subunit C. (843 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (747 aa)
TAF1DTATA-box binding protein associated factor, RNA polymerase I subunit D. (278 aa)
SMARCA5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (969 aa)
UBTFUpstream binding transcription factor. (701 aa)
BAZ1BBromodomain adjacent to zinc finger domain 1B. (1483 aa)
SAP18Sin3A associated protein 18. (172 aa)
MBD2Methyl-CpG binding domain protein 2. (262 aa)
SAP130Sin3A associated protein 130. (1056 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1135 aa)
POLR1ARNA polymerase I subunit A. (1720 aa)
TAF1ATATA-box binding protein associated factor, RNA polymerase I subunit A. (451 aa)
BAZ2BBromodomain adjacent to zinc finger domain 2B. (2213 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (128 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
TET3Tet methylcytosine dioxygenase 3. (1795 aa)
TTF1Transcription termination factor 1. (916 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (425 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1011 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
ENSCSAP00000009816Histone H3; Belongs to the histone H3 family. (136 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1076 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
BAZ2ABromodomain adjacent to zinc finger domain 2A. (1909 aa)
GATAD2AGATA-type domain-containing protein. (634 aa)
SIN3BSIN3 transcription regulator family member B. (1159 aa)
EP300E1A binding protein p300. (2416 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1006 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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