STRINGSTRING
DLL4 DLL4 JAG2 JAG2 NEURL1B NEURL1B DLK1 DLK1 DLL1 DLL1 ADAM10 ADAM10 ITCH ITCH APH1B APH1B NUMB NUMB PSEN1 PSEN1 ARRB2 ARRB2 JAG1 JAG1 CNTN1 CNTN1 NOTCH1 NOTCH1 PSEN2 PSEN2 MIB1 MIB1 APH1A APH1A DTX2 DTX2 NCSTN NCSTN DTX1 DTX1 UBC UBC MIB2 MIB2 ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018444 ENSCSAP00000018444 RPS27A RPS27A ADAM17 ADAM17 ARRB1 ARRB1 PSENEN PSENEN NEURL1 NEURL1 UBA52 UBA52 DTX4 DTX4 DNER DNER
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (555 aa)
DLK1Delta like non-canonical Notch ligand 1. (310 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
PSEN1Presenilin 1. (467 aa)
ARRB2Arrestin beta 2. (409 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
CNTN1Contactin 1. (1018 aa)
NOTCH1Notch receptor 1. (2555 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
DTX2Deltex E3 ubiquitin ligase 2. (622 aa)
NCSTNNicastrin. (709 aa)
DTX1Deltex E3 ubiquitin ligase 1. (624 aa)
UBCUncharacterized protein. (228 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (955 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
ARRB1Arrestin beta 1. (418 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
DNERDelta/notch like EGF repeat containing. (590 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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