STRINGSTRING
SHC1 SHC1 IGF1 IGF1 IGF1R IGF1R SOS1 SOS1 HRAS HRAS IGF2 IGF2 KRAS KRAS GRB2 GRB2 ERAS ERAS NRAS NRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHC1SHC adaptor protein 1. (474 aa)
IGF1Insulin like growth factor 1. (159 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
IGF2Insulin like growth factor 2. (236 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ERASES cell expressed Ras. (233 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.