STRINGSTRING
CCT7 CCT7 ENSCSAP00000011392 ENSCSAP00000011392 GNG2 GNG2 AP3M2 AP3M2 ARFGEF2 ARFGEF2 FKBP9 FKBP9 CCT4 CCT4 TUBA8 TUBA8 ARFGEF1 ARFGEF1 TUBAL3 TUBAL3 USP11 USP11 PDCL PDCL PDC PDC FBXW2 FBXW2 GNB4 GNB4 RGS11 RGS11 PFDN1 PFDN1 RGS6 RGS6 GNG11 GNG11 GNGT1 GNGT1 TCP1 TCP1 CCNE2 CCNE2 HDAC3 HDAC3 GNG10 GNG10 GNG13 GNG13 ERMARD ERMARD GNG7 GNG7 GNB5 GNB5 TP53 TP53 RGS9 RGS9 CCT2 CCT2 TBCB TBCB GAPDHS GAPDHS CSNK2A2 CSNK2A2 CCNE1 CCNE1 KIFC3 KIFC3 SPHK1 SPHK1 LONP2 LONP2 PFDN5 PFDN5 FBXW4 FBXW4 TUBA1A TUBA1A TUBA1C TUBA1C CCT6B CCT6B VBP1 VBP1 FBXW9 FBXW9 GNG3 GNG3 TUBB2A TUBB2A ARL2 ARL2 KIF13A KIF13A GNAQ GNAQ GNA14 GNA14 TUBA4A TUBA4A CDRT1 CDRT1 SKIV2L SKIV2L AP3M1 AP3M1 CCT8 CCT8 RGS7 RGS7 PFDN6 PFDN6 GNG4 GNG4 ENSCSAP00000006307 ENSCSAP00000006307 GNB3 GNB3 CSNK2A1 CSNK2A1 NOP56 NOP56 XRN2 XRN2 GNA15 GNA15 GNA11 GNA11 WRAP53 WRAP53 CCT8L2 CCT8L2 ENSCSAP00000018787 ENSCSAP00000018787 ENSCSAP00000018003 ENSCSAP00000018003 ENSCSAP00000017870 ENSCSAP00000017870 ENSCSAP00000017690 ENSCSAP00000017690 LOC103240948 LOC103240948 GNB1 GNB1 FBXO44 FBXO44 FBXO6 FBXO6 GNG12 GNG12 GBA GBA TBCD TBCD CCT3 CCT3 GNGT2 GNGT2 PFDN2 PFDN2 ENSCSAP00000015339 ENSCSAP00000015339 FKBP10 FKBP10 GNG8 GNG8 STAT3 STAT3 FBXW7 FBXW7 ENSCSAP00000014374 ENSCSAP00000014374 ENSCSAP00000014307 ENSCSAP00000014307 GNB2 GNB2 FBXL3 FBXL3 TUBB6 TUBB6 CCT5 CCT5 TUBA3D TUBA3D FBXO4 FBXO4 TUBB4B TUBB4B FBXL5 FBXL5 CCT6A CCT6A FBXW5 FBXW5 ENSCSAP00000012056 ENSCSAP00000012056 TUBB1 TUBB1 PFDN4 PFDN4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (542 aa)
ENSCSAP00000011392Tubulin-specific chaperone A; Belongs to the TBCA family. (60 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
AP3M2AP-3 complex subunit mu-2. (418 aa)
ARFGEF2ADP ribosylation factor guanine nucleotide exchange factor 2. (1597 aa)
FKBP9Peptidylprolyl isomerase. (570 aa)
CCT4T-complex protein 1 subunit delta. (539 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa)
ARFGEF1ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
PDCLPhosducin like. (301 aa)
PDCPhosducin. (246 aa)
FBXW2F-box and WD repeat domain containing 2. (454 aa)
GNB4G protein subunit beta 4. (340 aa)
RGS11Regulator of G protein signaling 11. (467 aa)
PFDN1Prefoldin subunit 1. (122 aa)
RGS6Regulator of G protein signaling 6. (430 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
TCP1T-complex 1. (556 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (383 aa)
HDAC3Hist_deacetyl domain-containing protein. (266 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG13G protein subunit gamma 13. (67 aa)
ERMARDER membrane associated RNA degradation. (436 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB5G protein subunit beta 5. (353 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
RGS9Regulator of G protein signaling 9. (671 aa)
CCT2Chaperonin containing TCP1 subunit 2. (535 aa)
TBCBTubulin folding cofactor B. (244 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (416 aa)
KIFC3Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1076 aa)
SPHK1Sphingosine kinase 1. (472 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (843 aa)
PFDN5Prefoldin subunit 5. (187 aa)
FBXW4F-box and WD repeat domain containing 4. (567 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
CCT6BChaperonin containing TCP1 subunit 6B. (558 aa)
VBP1Uncharacterized protein. (241 aa)
FBXW9F-box and WD repeat domain containing 9. (458 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
KIF13AKinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1799 aa)
GNAQG protein subunit alpha q. (301 aa)
GNA14G protein subunit alpha 14. (355 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
CDRT1WD_REPEATS_REGION domain-containing protein. (669 aa)
SKIV2LSki2 like RNA helicase. (1246 aa)
AP3M1AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
CCT8Chaperonin containing TCP1 subunit 8. (548 aa)
RGS7Regulator of G protein signaling 7. (469 aa)
PFDN6Prefoldin subunit 6. (129 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ENSCSAP00000006307CAP-Gly domain-containing protein. (492 aa)
GNB3G protein subunit beta 3. (340 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
NOP56NOP56 ribonucleoprotein. (594 aa)
XRN25'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (950 aa)
GNA15G protein subunit alpha 15. (374 aa)
GNA11G protein subunit alpha 11. (394 aa)
WRAP53WD repeat containing antisense to TP53. (549 aa)
CCT8L2Chaperonin containing TCP1 subunit 8 like 2. (556 aa)
ENSCSAP00000018787Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCSAP00000018003Uncharacterized protein. (108 aa)
ENSCSAP00000017870Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. (197 aa)
ENSCSAP00000017690Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC103240948Uncharacterized protein. (375 aa)
GNB1G protein subunit beta 1. (340 aa)
FBXO44F-box protein 44. (224 aa)
FBXO6F-box protein 6. (293 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GBAGlucosylceramidase. (536 aa)
TBCDTubulin folding cofactor D. (1192 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PFDN2Prefoldin subunit 2. (154 aa)
ENSCSAP00000015339Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
ENSCSAP00000014374annotation not available (297 aa)
ENSCSAP00000014307Uncharacterized protein. (510 aa)
GNB2G protein subunit beta 2. (340 aa)
FBXL3F-box and leucine rich repeat protein 3. (428 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
TUBA3DTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
FBXO4F-box protein 4. (387 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
FBXL5F-box and leucine rich repeat protein 5. (691 aa)
CCT6AUncharacterized protein. (453 aa)
FBXW5F-box and WD repeat domain containing 5. (566 aa)
ENSCSAP00000012056Tubulin domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (417 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PFDN4Prefoldin subunit 4; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit beta family. (134 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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