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CACNG8 CACNG8 AKAP5 AKAP5 AP2B1 AP2B1 PRKCG PRKCG AP2A1 AP2A1 ENSCSAP00000015592 ENSCSAP00000015592 GRIA4 GRIA4 GRIA2 GRIA2 GRIA3 GRIA3 MYO6 MYO6 CAMK2B CAMK2B TSPAN7 TSPAN7 AP2M1 AP2M1 DLG4 DLG4 CAMK2A CAMK2A GRIA1 GRIA1 AP2A2 AP2A2 TSPAN6 TSPAN6 NSF NSF ENSCSAP00000000163 ENSCSAP00000000163 PRKCA PRKCA CACNG4 CACNG4 MDM2 MDM2 GRIP1 GRIP1 TMEM35A TMEM35A EPB41L1 EPB41L1 GRIP2 GRIP2 CAMK2G CAMK2G DLG1 DLG1 CACNG2 CACNG2 PICK1 PICK1 PRKCB PRKCB CACNG3 CACNG3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (421 aa)
AKAP5A-kinase anchoring protein 5. (427 aa)
AP2B1AP complex subunit beta. (951 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
AP2A1Alpha_adaptinC2 domain-containing protein. (817 aa)
ENSCSAP00000015592Adaptin_N domain-containing protein. (132 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (811 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
TSPAN7Tetraspanin. (249 aa)
AP2M1Adaptor related protein complex 2 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (251 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (724 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (811 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
TSPAN6Tetraspanin. (245 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (769 aa)
ENSCSAP00000000163Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
GRIP1Glutamate receptor interacting protein 1. (1113 aa)
TMEM35ATransmembrane protein 35A. (167 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (1559 aa)
GRIP2Glutamate receptor interacting protein 2. (1048 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
DLG1Uncharacterized protein; Belongs to the MAGUK family. (800 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
PICK1Protein interacting with PRKCA 1. (415 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
CACNG3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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