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| | NLRP6 | NLR family pyrin domain containing 6. (894 aa) |
| | IL1RAP | Interleukin 1 receptor accessory protein. (570 aa) |
| | APP | Amyloid beta precursor protein. (770 aa) |
| | GSDMD | Gasdermin D. (424 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa) |
| | ENSCSAP00000005494 | ANK_REP_REGION domain-containing protein. (217 aa) |
| | AGER | Advanced glycosylation end-product specific receptor. (403 aa) |
| | PSMB8 | Proteasome subunit beta. (308 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | FBXW11 | F-box and WD repeat domain containing 11. (510 aa) |
| | NKIRAS1 | NFKB inhibitor interacting Ras like 1. (192 aa) |
| | TOLLIP | Toll interacting protein. (274 aa) |
| | PTPN20 | Protein tyrosine phosphatase non-receptor type 20. (420 aa) |
| | IRAK2 | Interleukin 1 receptor associated kinase 2. (626 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (496 aa) |
| | SIGIRR | Single Ig and TIR domain containing. (410 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (377 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | PTPN21 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1165 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PTPN12 | Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (780 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | LRRC74A | Leucine rich repeat containing 74A. (489 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (412 aa) |
| | MFSD1 | Major facilitator superfamily domain containing 1. (465 aa) |
| | LRRC34 | Leucine rich repeat containing 34. (403 aa) |
| | LRRC31 | Leucine rich repeat containing 31. (552 aa) |
| | ENSCSAP00000008892 | Uncharacterized protein. (190 aa) |
| | LRRC74B | Leucine rich repeat containing 74B. (393 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (443 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
| | IL13 | Interleukin 13. (146 aa) |
| | PSME4 | Proteasome activator subunit 4. (1843 aa) |
| | PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (330 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa) |
| | IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (413 aa) |
| | ENSCSAP00000010424 | Uncharacterized protein. (171 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | PTPN9 | Protein tyrosine phosphatase non-receptor type 9. (593 aa) |
| | PELI2 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa) |
| | MAP3K20 | Protein kinase domain-containing protein. (292 aa) |
| | ENSCSAP00000010823 | Protein kinase domain-containing protein. (169 aa) |
| | PELI1 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | TMEM189-UBE2V1 | TMEM189-UBE2V1 readthrough. (370 aa) |
| | ENSCSAP00000011477 | Uncharacterized protein. (207 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | NFKBIA | NFKB inhibitor alpha. (317 aa) |
| | PTPN14 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | TNIP2 | TNFAIP3 interacting protein 2. (429 aa) |
| | CTSG | Cathepsin G; Belongs to the peptidase S1 family. (255 aa) |
| | KHNYN | KH and NYN domain containing. (678 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (325 aa) |
| | PTPN23 | Protein tyrosine phosphatase non-receptor type 23. (1632 aa) |
| | TRAF2 | TNF receptor-associated factor. (449 aa) |
| | PSME2 | Proteasome activator subunit 2. (253 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSME1 | Proteasome activator subunit 1. (238 aa) |
| | PTPN4 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa) |
| | IL1RN | Interleukin-1. (177 aa) |
| | IL1F10 | Interleukin 1 family member 10. (152 aa) |
| | IL36RN | Interleukin-1. (155 aa) |
| | IL36B | Interleukin-1. (160 aa) |
| | IL36A | Interleukin-1. (160 aa) |
| | IL36G | Interleukin-1. (170 aa) |
| | IL37 | Interleukin-1. (219 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa) |
| | IL1A | Interleukin-1; Belongs to the IL-1 family. (224 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (620 aa) |
| | PTPN18 | Protein tyrosine phosphatase non-receptor type 18. (456 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (598 aa) |
| | IL18R1 | Interleukin 18 receptor 1. (539 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (556 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (575 aa) |
| | IL1R1 | Interleukin 1 receptor type 1. (569 aa) |
| | IL1R2 | Interleukin 1 receptor type 2. (418 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | PTPN2 | Protein tyrosine phosphatase non-receptor type 2. (298 aa) |
| | ENSCSAP00000013550 | PROTEASOME_ALPHA_1 domain-containing protein. (218 aa) |
| | USP14 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (467 aa) |
| | PSME3 | Proteasome activator subunit 3. (267 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | CASP12 | Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa) |
| | CASP1 | Caspase 1; Belongs to the peptidase C14A family. (462 aa) |
| | NKIRAS2 | NFKB inhibitor interacting Ras like 2. (191 aa) |
| | CARD16 | CARD domain-containing protein. (81 aa) |
| | ENSCSAP00000014978 | Uncharacterized protein; Belongs to the peptidase C14A family. (392 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | NLRX1 | NLR family member X1. (972 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa) |
| | LRRC71 | Leucine rich repeat containing 71. (559 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | LRRC45 | Leucine rich repeat containing 45. (670 aa) |
| | UBC | Uncharacterized protein. (228 aa) |
| | S100A12 | S100 calcium binding protein A12; Belongs to the S-100 family. (91 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | ENSCSAP00000016317 | Uncharacterized protein. (992 aa) |
| | NLRP13 | NLR family pyrin domain containing 13. (1045 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSCSAP00000017575 | Ubiquitin-like domain-containing protein. (156 aa) |
| | TIFA | TRAF interacting protein with forkhead associated domain. (185 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | ENSCSAP00000017765 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSCSAP00000018133 | Uncharacterized protein. (215 aa) |
| | ENSCSAP00000018444 | Ubiquitin-like domain-containing protein. (127 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | CCDC71L | Coiled-coil domain containing 71 like. (235 aa) |
| | PSMB11 | Proteasome subunit beta. (300 aa) |
| | ENSCSAP00000000080 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | ALPK1 | Alpha kinase 1. (1181 aa) |
| | MAP3K3 | Mitogen-activated protein kinase kinase kinase 3. (657 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (969 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (287 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | IL18BP | Interleukin 18 binding protein. (194 aa) |
| | PTPN13 | Protein tyrosine phosphatase non-receptor type 13. (2487 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | IRAK3 | Interleukin 1 receptor associated kinase 3. (596 aa) |
| | TBK1 | TANK binding kinase 1. (729 aa) |
| | PSMA1 | Proteasome subunit alpha type. (130 aa) |
| | NLRC5 | NLR family CARD domain containing 5. (1865 aa) |
| | SAA4 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa) |
| | LOC103239253 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | LOC103239243 | Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa) |
| | PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (565 aa) |
| | NOD2 | Nucleotide binding oligomerization domain containing 2. (1036 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | N4BP1 | NEDD4 binding protein 1. (810 aa) |
| | NFKB2 | Nuclear factor kappa B subunit 2. (899 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa) |
| | BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (460 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (686 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | S100B | Protein S100; Belongs to the S-100 family. (92 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | PELI3 | E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (445 aa) |
| | LRRC14 | Leucine rich repeat containing 14. (493 aa) |
| | SQSTM1 | Sequestosome 1. (440 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1377 aa) |
| | IL33 | Interleukin 33. (270 aa) |
